Escherichia coli mutant Y16 is a double mutant carrying thermosensitive ftsH and ftsI mutations

K J Begg; T Tomoyasu; W D Donachie; M Khattar; H Niki; K Yamanaka; S Hiraga; T Ogura

doi:10.1128/jb.174.7.2416-2417.1992

Escherichia coli mutant Y16 is a double mutant carrying thermosensitive ftsH and ftsI mutations

J Bacteriol. 1992 Apr;174(7):2416-7. doi: 10.1128/jb.174.7.2416-2417.1992.

Authors

K J Begg¹, T Tomoyasu, W D Donachie, M Khattar, H Niki, K Yamanaka, S Hiraga, T Ogura

Affiliation

¹ Institute of Cell and Molecular Biology, University of Edinburgh, Scotland.

Abstract

The Escherichia coli mutant Y16, which shows thermosensitive colony formation and filamentation with reduced amounts of penicillin-binding protein 3 (PBP3), has mutations in the ftsI gene encoding PBP3 and in the ftsH gene. The ftsI mutation markedly reduces the amount of PBP3 at 42 degrees C, whereas the amount of the ftsH single mutant is slightly reduced.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / genetics*
Cell Division
Escherichia coli / genetics*
Genes, Bacterial
Genetic Complementation Test
Mutation
Temperature

Substances

Bacterial Proteins