Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients

J Med Genet. 2004 Jun;41(6):e89. doi: 10.1136/jmg.2003.015594.

Authors

G Keller¹, H Vogelsang, I Becker, S Plaschke, K Ott, G Suriano, A R Mateus, R Seruca, K Biedermann, D Huntsman, C Döring, E Holinski-Feder, A Neutzling, J R Siewert, H Höfler

Affiliation

¹ Institute of Pathology, Klinikum rechts der Isar, Technische Universität München, Germany. gisela.keller@lrz.tum.de

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
CHO Cells
Cadherins / genetics*
Core Binding Factor Alpha 3 Subunit
Cricetinae
Cricetulus
DNA / chemistry
DNA / genetics
DNA Mutational Analysis / methods
DNA-Binding Proteins / genetics
Family Health
Female
Genetic Predisposition to Disease / genetics*
Germ-Line Mutation*
Humans
Immunohistochemistry
Male
Membrane Proteins / genetics
Neoplasm Proteins / genetics
Pedigree
Stomach Neoplasms / genetics*
Stomach Neoplasms / pathology
Transcription Factors / genetics
Tumor Suppressor Protein p53 / analysis
Tumor Suppressor Protein p53 / genetics*

Substances

Cadherins
Core Binding Factor Alpha 3 Subunit
DNA-Binding Proteins
Membrane Proteins
Neoplasm Proteins
Runx3 protein, human
TMEFF2 protein, human
Transcription Factors
Tumor Suppressor Protein p53
DNA