The collagen receptor subfamily of the integrins

Int J Biochem Cell Biol. 2004 Aug;36(8):1405-10. doi: 10.1016/j.biocel.2003.08.016.

Abstract

The four collagen receptor integrins, alpha1beta1, alpha2beta1, alpha10beta1 and alpha11beta1, form a structurally and functionally distinct subgroup when compared to other members of the integrin family. In this review, we discuss the structures of these receptors and their differences in collagen binding and signalling function.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Integrins / chemistry*
  • Integrins / metabolism
  • Integrins / physiology
  • Ligands
  • Protein Binding
  • Protein Structure, Tertiary
  • Receptors, Collagen / chemistry*
  • Receptors, Collagen / metabolism
  • Receptors, Collagen / physiology
  • Signal Transduction

Substances

  • Integrins
  • Ligands
  • Receptors, Collagen