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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2004 | 1 |
2006 | 1 |
2008 | 1 |
2024 | 0 |
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Page 1
The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation.
EMBO J. 2004 May 19;23(10):2071-82. doi: 10.1038/sj.emboj.7600218. Epub 2004 Apr 29.
EMBO J. 2004.
PMID: 15116068
Free PMC article.
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.
Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y, Matsuda T, Takeda A, Tsuchihashi D, Nishizawa A, Ogawa W, Fujimoto Y, Okamura H, Arden KC, Herrera PL, Noda T, Kasuga M.
Hashimoto N, et al.
Nat Genet. 2006 May;38(5):589-93. doi: 10.1038/ng1774. Epub 2006 Apr 23.
Nat Genet. 2006.
PMID: 16642023
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Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR.
Bayascas JR, et al.
Mol Cell Biol. 2008 May;28(10):3258-72. doi: 10.1128/MCB.02032-07. Epub 2008 Mar 17.
Mol Cell Biol. 2008.
PMID: 18347057
Free PMC article.
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