Molecular cloning and sequence analysis of a chicken ornithine decarboxylase cDNA

Anim Genet. 1992;23(5):403-9. doi: 10.1111/j.1365-2052.1992.tb02158.x.

Abstract

A chicken embryo cDNA library was screened with a mouse probe for ornithine decarboxylase (ODC) and 14 positively hybridizing clones isolated. The longest of these (1.7 kb) was sub-cloned and sequenced. It is estimated that the clone comprises approximately 98% of the coding region for chicken ODC. The DNA sequence shows 78% identity with the human ODC cDNA sequence and the deduced amino acid sequence is almost 90% homologous to mouse and human. Both the peptide and cDNA sequences show interesting potential regulatory features which are discussed here.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Chick Embryo
  • Chickens / genetics*
  • Cloning, Molecular
  • DNA
  • Genomic Library
  • Humans
  • Molecular Sequence Data
  • Ornithine Decarboxylase / genetics*
  • Sequence Homology, Amino Acid

Substances

  • DNA
  • Ornithine Decarboxylase

Associated data

  • GENBANK/X64710