Expression pattern of the activin receptor type II...[FEBS Lett. 1992]

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1: FEBS Lett. 1992 Jun 1;303(2-3):185-9. Links

Expression pattern of the activin receptor type IIA gene during differentiation of chick neural tissues, muscle and skin.

Ohuchi H, Noji S, Koyama E, Myokai F, Nishikawa K, Nohno T, Tashiro K, Shiokawa K, Matsuo N, Taniguchi S.

Department of Ophthalmology, Okayama University Medical School, Japan.

To elucidate target cells of activins during embryogenesis we isolated cDNAs of chick activin receptor type II (cActR-II) and studied expression patterns of the cActR-II gene by in situ hybridization. Transcripts of cActR-II were observed in neuroectoderm developing to spinal cord, brain and eyes, in surface ectoderm differentiating to epidermis, and in myotomes differentiating to muscles. The expression patterns of cActR-II suggest that activin and its receptor are involved in differentiation of chick neural tissues, muscle and skin after inducing the dorsal mesoderm.

PMID: 1318847 [PubMed - indexed for MEDLINE]

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Expression pattern of the activin receptor type IIA gene during differentiation of chick neural tissues, muscle and skin.

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