Abstract
Puromycin-sensitive aminopeptidase is a predominantly cytoplasmatic zinc-dependent exopeptidase. Its physiological function is not known to date. Here we report data on tissue distribution, a polymorphism within the coding region and the complete 3' UTR. The gene (NPEPPS alias PSA) was physically mapped to chromosome 17q21.2-->q21.32 using fluorescence in situ hybridization.
Copyright 2001 S. Karger AG, Basel.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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3' Untranslated Regions / genetics*
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Amino Acid Sequence
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Aminopeptidases / genetics*
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Base Sequence
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Chromosome Banding
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Chromosomes, Human, Pair 17 / genetics*
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Cloning, Molecular
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DNA, Complementary / genetics
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Expressed Sequence Tags
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Gene Expression Profiling
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Gene Expression Regulation / drug effects
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Humans
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In Situ Hybridization, Fluorescence
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Physical Chromosome Mapping
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Polymorphism, Genetic / genetics*
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RNA, Messenger / analysis
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RNA, Messenger / genetics
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Sequence Alignment
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Vitamin D / pharmacology
Substances
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3' Untranslated Regions
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DNA, Complementary
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RNA, Messenger
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Vitamin D
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Aminopeptidases
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enkephalin degrading enzyme