Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors

Lab Invest. 2001 Jun;81(6):777-90. doi: 10.1038/labinvest.3780288.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • DNA Replication / drug effects*
  • DNA, Mitochondrial / drug effects*
  • DNA, Mitochondrial / genetics*
  • Humans
  • Mutation / physiology*
  • Nucleosides / poisoning*
  • Oxidative Stress*
  • Reverse Transcriptase Inhibitors / poisoning*

Substances

  • DNA, Mitochondrial
  • Nucleosides
  • Reverse Transcriptase Inhibitors