A new region of synteny between human chromosome 1p22 and mouse chromosome 5

Int J Mol Med. 2000 May;5(5):553-6. doi: 10.3892/ijmm.5.5.553.

Abstract

By constructing a physical map of the p22 region of human chromosome 1 we have been able to show the relative orientation of four genes; GFI1, NB4S/EVI5, RPL5 and DR1. Analysis of the mouse physical map shows that the murine orthologs of these genes are located on mouse chromosome 5. Through this analysis we have established a new region of synteny between mouse chromosome 5 and human chromosome region 1p22.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Cycle Proteins
  • Chromosome Mapping
  • Chromosomes
  • Chromosomes, Artificial, Yeast
  • Chromosomes, Human, Pair 1*
  • DNA-Binding Proteins / genetics
  • GTPase-Activating Proteins
  • Humans
  • Mice
  • Phosphoproteins / genetics
  • Ribosomal Proteins / genetics
  • Transcription Factors / genetics

Substances

  • Cell Cycle Proteins
  • DNA-Binding Proteins
  • Evi5 protein, mouse
  • GFI1 protein, human
  • GTPase-Activating Proteins
  • Gfi1 protein, mouse
  • Phosphoproteins
  • Ribosomal Proteins
  • Transcription Factors
  • down-regulator of transcription 1
  • ribosomal protein L5