Abstract
By constructing a physical map of the p22 region of human chromosome 1 we have been able to show the relative orientation of four genes; GFI1, NB4S/EVI5, RPL5 and DR1. Analysis of the mouse physical map shows that the murine orthologs of these genes are located on mouse chromosome 5. Through this analysis we have established a new region of synteny between mouse chromosome 5 and human chromosome region 1p22.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cell Cycle Proteins
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Chromosome Mapping
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Chromosomes
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Chromosomes, Artificial, Yeast
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Chromosomes, Human, Pair 1*
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DNA-Binding Proteins / genetics
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GTPase-Activating Proteins
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Humans
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Mice
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Phosphoproteins / genetics
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Ribosomal Proteins / genetics
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Transcription Factors / genetics
Substances
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Cell Cycle Proteins
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DNA-Binding Proteins
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Evi5 protein, mouse
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GFI1 protein, human
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GTPase-Activating Proteins
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Gfi1 protein, mouse
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Phosphoproteins
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Ribosomal Proteins
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Transcription Factors
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down-regulator of transcription 1
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ribosomal protein L5