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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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1999 | 1 |
2004 | 1 |
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2016 | 1 |
2019 | 1 |
2021 | 1 |
2022 | 1 |
2024 | 0 |
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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
Cell. 1999 Oct 29;99(3):247-57. doi: 10.1016/s0092-8674(00)81656-6.
Cell. 1999.
PMID: 10555141
Free article.
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan.
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R.
Nguyen S, et al.
Dev Dyn. 2007 Jun;236(6):1663-76. doi: 10.1002/dvdy.21176.
Dev Dyn. 2007.
PMID: 17477386
Free article.
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Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Scheller M, Ludwig AK, Göllner S, Rohde C, Krämer S, Stäble S, Janssen M, Müller JA, He L, Bäumer N, Arnold C, Gerß J, Schönung M, Thiede C, Niederwieser C, Niederwieser D, Serve H, Berdel WE, Thiem U, Hemmerling I, Leuschner F, Plass C, Schlesner M, Zaugg J, Milsom MD, Trumpp A, Pabst C, Lipka DB, Müller-Tidow C.
Scheller M, et al.
Nat Cancer. 2021 May;2(5):527-544. doi: 10.1038/s43018-021-00213-9. Epub 2021 May 25.
Nat Cancer. 2021.
PMID: 35122024
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Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.
Loberg MA, Bell RK, Goodwin LO, Eudy E, Miles LA, SanMiguel JM, Young K, Bergstrom DE, Levine RL, Schneider RK, Trowbridge JJ.
Loberg MA, et al.
Leukemia. 2019 Jul;33(7):1635-1649. doi: 10.1038/s41375-018-0368-6. Epub 2019 Jan 28.
Leukemia. 2019.
PMID: 30692594
Free PMC article.
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DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.
Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G, Rivera SA, Chramiec AG, Pronier E, Bastian L, Keller MD, Tovbin D, Loizou E, Weinstein AR, Gonzalez AR, Lieu YK, Rowe JM, Pastore F, McKenney AS, Krivtsov AV, Sperr WR, Cross JR, Mason CE, Tallman MS, Arcila ME, Abdel-Wahab O, Armstrong SA, Kubicek S, Staber PB, Gönen M, Paietta EM, Melnick AM, Nimer SD, Mukherjee S, Levine RL.
Guryanova OA, et al.
Nat Med. 2016 Dec;22(12):1488-1495. doi: 10.1038/nm.4210. Epub 2016 Nov 14.
Nat Med. 2016.
PMID: 27841873
Free PMC article.
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Heterozygous Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool.
Higo T, Suzuki Y, Sato M, Koya J, Mizuno H, Miyauchi M, Masamoto Y, Kataoka K, Sumitomo Y, Tsuruta-Kishino T, Sato T, Kurokawa M.
Higo T, et al.
Exp Hematol. 2022 May;109:45-54. doi: 10.1016/j.exphem.2022.02.006. Epub 2022 Mar 1.
Exp Hematol. 2022.
PMID: 35245608
Free article.
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Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.
Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H.
Kaneda M, et al.
Nature. 2004 Jun 24;429(6994):900-3. doi: 10.1038/nature02633.
Nature. 2004.
PMID: 15215868
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