c-Irx2 expression reveals an early subdivision of the neural plate in the chick embryo

Mech Dev. 1999 Sep;87(1-2):203-6. doi: 10.1016/s0925-4773(99)00149-5.

Abstract

We have cloned c-Irx2, a chick homologue of the Xiro2 and mIrx2 genes and a new member of the Iroquois family of homeodomain-containing transcription factors. Strikingly, c-Irx2 expression reveals an early subdivision of the neural plate at late primitive streak stages which later transiently resolves to a single stripe within the developing hindbrain corresponding to rhombomere 1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Cerebellum / embryology
  • Cerebellum / metabolism
  • Chick Embryo
  • DNA, Complementary / metabolism
  • Gene Expression*
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / metabolism*
  • Mesencephalon / embryology
  • Mesencephalon / metabolism*
  • Molecular Sequence Data
  • Rhombencephalon / embryology
  • Rhombencephalon / metabolism*
  • Sequence Homology, Amino Acid
  • Time Factors
  • Transcription Factors / genetics
  • Transcription Factors / metabolism*

Substances

  • DNA, Complementary
  • Homeodomain Proteins
  • Transcription Factors

Associated data

  • GENBANK/AJ237599