LOCUS       YP_001208558             364 aa            linear   BCT 18-JUL-2008
DEFINITION  dihydroorotate dehydrogenase 2 [Bradyrhizobium sp. ORS278].
ACCESSION   YP_001208558
VERSION     YP_001208558.1  GI:146343510
DBSOURCE    REFSEQ: accession NC_009445.1
KEYWORDS    .
SOURCE      Bradyrhizobium sp. ORS278
  ORGANISM  Bradyrhizobium sp. ORS278
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
            Bradyrhizobiaceae; Bradyrhizobium.
REFERENCE   1  (residues 1 to 364)
  AUTHORS   Giraud,E., Moulin,L., Vallenet,D., Barbe,V., Cytryn,E.,
            Avarre,J.C., Jaubert,M., Simon,D., Cartieaux,F., Prin,Y., Bena,G.,
            Hannibal,L., Fardoux,J., Kojadinovic,M., Vuillet,L., Lajus,A.,
            Cruveiller,S., Rouy,Z., Mangenot,S., Segurens,B., Dossat,C.,
            Franck,W.L., Chang,W.S., Saunders,E., Bruce,D., Richardson,P.,
            Normand,P., Dreyfus,B., Pignol,D., Stacey,G., Emerich,D.,
            Vermeglio,A., Medigue,C. and Sadowsky,M.
  TITLE     Legumes symbioses: absence of Nod genes in photosynthetic
            bradyrhizobia
  JOURNAL   Science 316 (5829), 1307-1312 (2007)
   PUBMED   17540897
REFERENCE   2  (residues 1 to 364)
  AUTHORS   Jaubert,M., Lavergne,J., Fardoux,J., Hannibal,L., Vuillet,L.,
            Adriano,J.M., Bouyer,P., Pignol,D., Giraud,E. and Vermeglio,A.
  TITLE     A singular bacteriophytochrome acquired by lateral gene transfer
  JOURNAL   Unpublished
REFERENCE   3  (residues 1 to 364)
  AUTHORS   Genoscope.
  CONSRTM   1:Genoscope, UMR 8030, France 2:LSTM, France 3:Dep SWC ; and
            BioTechnology Institute, USA 4:CEA/Cadarache,DEVM,UMR 6191, France
            5:NCSB , USA 6:DOE , USA 7:DOE , USA 8:Universite Lyon1, France;
            UMR5557, France; IFR 41, France.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2006) Genoscope - Centre National de Sequencage :
            BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr
            - Web : www.genoscope.cns.fr)
REFERENCE   4  (residues 1 to 364)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAL80343.
            Annotation data relative to BLAST similarities, COG assignations,
            enzymatic function prediction (PRIAM software), TMHMM and SignalP
            predictions, and synteny results (Syntonizer software) are
            available in FrankiaScope database via the MaGe annotation system
            http://www.genoscope.cns.fr/agc/mage/frankia.
            Each annotation includes a confidence level as follow: 1 : Function
            experimentally demonstrated in the studied organism 2a : Function
            of homologous gene experimentally demonstrated in an other organism
            2b : Function of strongly homologous gene
            3 : Function proposed based on presence of conserved amino acid
            motif, structural feature or limited homology
            4 : Homologs of previously reported genes of unknown function 5 :
            No homology to any previously reported sequences 6 : Doubtful CDS
            7 : Gene remnant.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Bradyrhizobium sp. ORS278"
                     /strain="ORS278"
                     /db_xref="taxon:114615"
     Protein         1..364
                     /product="dihydroorotate dehydrogenase 2"
                     /EC_number="1.3.3.1"
                     /function="1.5.2.2 : Pyrimidine biosynthesis"
                     /function="7.1 : Cytoplasm"
                     /calculated_mol_wt=39077
     CDS             1..364
                     /gene="pyrD"
                     /locus_tag="BRADO6742"
                     /coded_by="complement(NC_009445.1:7003804..7004898)"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /note="catalyzes the conversion of dihydroorotate to
                     orotate in the pyrimidine biosynthesis pathway; uses a
                     flavin nucleotide as an essential cofactor; class 2
                     enzymes are monomeric and compared to the class 1 class 2
                     possess an extended N terminus, which plays a role in the
                     membrane association of the enzyme and provides the
                     binding site for the respiratory quinones that serve as
                     physiological electron acceptors"
                     /transl_table=11
                     /db_xref="GeneID:5119338"
ORIGIN      
        1 mirafdqlsl pllrwldaed ahrlaiqglk llpavkprad daklavrafg lnfpnpvgma
       61 agfdknaevp dallrlgfgf veigsvtprp qsgnprprlf rlerdeavin rmgfnndgae
      121 ivlrrlagra nqggivgvnv gankdsadrv adyvrlietf apvasyftvn isspntpglr
      181 nlqqasqldd lltkvleard rvrrkagdtp vllkiapdls laelddvvhv arsrgvdgmi
      241 vsnttlarpn slreqmrake qgglsgrplf rlstrmvaet fvrvegafpl igvggidtgg
      301 aaltkiraga sliqlysslv ykglglvesi kadltstllr tgreslseiv gadaatitae
      361 dwpv
//