LOCUS       NP_856048                431 aa            linear   BCT 21-JUL-2008
DEFINITION  lysine-N-oxygenase MBTG (L-lysine 6-monooxygenase) (lysine
            N6-hydroxylase) [Mycobacterium bovis AF2122/97].
ACCESSION   NP_856048
VERSION     NP_856048.1  GI:31793555
DBSOURCE    REFSEQ: accession NC_002945.3
KEYWORDS    complete genome.
SOURCE      Mycobacterium bovis AF2122/97
  ORGANISM  Mycobacterium bovis AF2122/97
            Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
            Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
            tuberculosis complex.
REFERENCE   1  (residues 1 to 431)
  AUTHORS   Garnier,T., Eiglmeier,K., Camus,J.C., Medina,N., Mansoor,H.,
            Pryor,M., Duthoy,S., Grondin,S., Lacroix,C., Monsempe,C., Simon,S.,
            Harris,B., Atkin,R., Doggett,J., Mayes,R., Keating,L.,
            Wheeler,P.R., Parkhill,J., Barrell,B.G., Cole,S.T., Gordon,S.V. and
            Hewinson,R.G.
  TITLE     The complete genome sequence of Mycobacterium bovis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 100 (13), 7877-7882 (2003)
   PUBMED   12788972
REFERENCE   2  (residues 1 to 431)
  AUTHORS   Garnier,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2003) Unite de Genetique Moleculaire Bacterienne
            Institut Pasteur, 28 rue du Docteur Roux, Paris Cedex 15 75724,
            France
  REMARK    TB Research Group, Veterinary Laboratories, Agency Weybridge,
            Woodham Lane, New Haw,Addlestone,   Surrey KT15 3NB, UK, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton,Cambridge CB10 1SA,
            UK, Genopole, Institut Pasteur, 28 Rue du Docteur Roux, 75724 Paris
            Cedex 15, France.
REFERENCE   3  (residues 1 to 431)
  CONSRTM   NCBI Microbial Genomes Annotation Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAR-2003) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (residues 1 to 431)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-APR-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CAD97260.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Mycobacterium bovis AF2122/97"
                     /strain="AF2122/97"
                     /db_xref="taxon:233413"
     Protein         1..431
                     /product="lysine-N-oxygenase MBTG (L-lysine
                     6-monooxygenase) (lysine N6-hydroxylase)"
                     /EC_number="1.14.13.59"
                     /calculated_mol_wt=46813
     CDS             1..431
                     /gene="mbtG"
                     /locus_tag="Mb2399c"
                     /coded_by="complement(NC_002945.3:2624479..2625774)"
                     /note="Mb2399c, mbtG, len: 431 aa. Equivalent to Rv2378c,
                     len: 431 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 431 aa overlap). mbtG, lysine-N
                     -oxygenase (hydroxylase) (EC 1.14.13.59) showing some
                     similarity with various proteins including ornithine and
                     lysine-N-oxygenases, e.g. Q9K6Q1|TRKA|BH3677 POTASSIUM
                     UPTAKE PROTEIN from Bacillus halodurans (350 aa), FASTA
                     scores: opt: 153, E(): 0.016, (25.2% identity in 246 aa
                     overlap); P56584|SID1_USTMA L-ORNITHINE 5-MONOOXYGENASE
                     (EC 1.13.12.-) from Ustilago maydis (Smut fungus) (570
                     aa), FASTA scores: opt: 136, E(): 0.31, (22.85% identity
                     in 127 aa overlap); Q9HHV0|HXYA|VNG6214G MONOOXYGENASE
                     from Halobacterium sp. strain NRC-1 (477 aa), FASTA
                     scores: opt: 119, E(): 3.4, (40.0% identity in 70 aa
                     overlap); O69828|SC1A6.23 PUTATIVE LYSINE N-HYDROXLASE
                     (FRAGMENT) from Streptomyces coelicolor (134 aa), BLAST
                     score: 76 (similarity in part for this one); etc.
                     COFACTORS: FAD (BY SIMILARITY)."
                     /transl_table=11
                     /db_xref="GeneID:1094387"
ORIGIN      
        1 mnptlavlga gakavavaak asvlrdmgvd vpdviaveri gvganwqasg gwtdgahrlg
       61 tspekdvgfp yrsalvprrn aeldermtry swqsyliata sfaewidrgr papthrrwsq
      121 ylawvadhig lkvihgever lavtgdrwal cthettvqad almitgpgqa eksllpgnpr
      181 vlsiaqfwdr aaghdrinae rvaviggget aasmlnelfr hrvstitvis pqvtlftrge
      241 gffenslfsd ptdwaaltfd errdalartd rgvfsatvqe alladdrihh lrgrvahavg
      301 rqgqirltls tnrgsenfet vhgfdlvidg sgadplwfts lfsqhtldll elglggplta
      361 drlqeaigyd lavtdvtpkl flptlsgltq gpgfpnlscl gllsdrvlga giftptkhnd
      421 trrsgehqsf r
//