LOCUS       NP_851939                222 aa            linear   PRI 22-OCT-2008
DEFINITION  FK506 binding protein 7 isoform a precursor [Homo sapiens].
ACCESSION   NP_851939
VERSION     NP_851939.1  GI:31317231
DBSOURCE    REFSEQ: accession NM_181342.2
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 222)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res. 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE   2  (residues 1 to 222)
  AUTHORS   Patterson,C.E., Gao,J., Rooney,A.P. and Davis,E.C.
  TITLE     Genomic organization of mouse and human 65 kDa FK506-binding
            protein genes and evolution of the FKBP multigene family
  JOURNAL   Genomics 79 (6), 881-889 (2002)
   PUBMED   12036304
REFERENCE   3  (residues 1 to 222)
  AUTHORS   Nakamura,T., Yabe,D., Kanazawa,N., Tashiro,K., Sasayama,S. and
            Honjo,T.
  TITLE     Molecular cloning, characterization, and chromosomal localization
            of FKBP23, a novel FK506-binding protein with Ca2+-binding ability
  JOURNAL   Genomics 54 (1), 89-98 (1998)
   PUBMED   9806833
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA020387.1, BC009711.1,
            AC009948.3 and AA447628.1.
            
            Summary: The protein encoded by this gene belongs to the FKBP-type
            peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of
            this family exhibit PPIase activity and function as molecular
            chaperones. A similar protein in mouse is located in the
            endoplasmic reticulum and binds calcium. [provided by RefSeq].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.2"
     Protein         1..222
                     /product="FK506 binding protein 7 isoform a precursor"
                     /EC_number="5.2.1.8"
                     /note="peptidyl-prolyl cis-trans isomerase; rotamase;
                     FK506-binding protein 7; FK506-binding protein 23"
     sig_peptide     1..23
                     /calculated_mol_wt=2914
     mat_peptide     24..222
                     /product="FK506 binding protein 7 isoform a"
                     /calculated_mol_wt=22899
     CDS             1..222
                     /gene="FKBP7"
                     /gene_synonym="FKBP23"
                     /gene_synonym="PPIase"
                     /gene_synonym="MGC9420"
                     /coded_by="NM_181342.2:130..798"
                     /note="isoform a precursor is encoded by transcript
                     variant 1"
                     /db_xref="CCDS:CCDS2280.1"
                     /db_xref="GeneID:51661"
                     /db_xref="HGNC:3723"
                     /db_xref="MIM:607062"
ORIGIN      
        1 mpktmhflfr fivffylwgl ftaqrqkkee steevkievl hrpencskts kkgdllnahy
       61 dgylakdgsk fycsrtqneg hpkwfvlgvg qvikgldiam tdmcpgekrk vvippsfayg
      121 kegyaegkip pdatlifeie lyavtkgprs ietfkqidmd ndrqlskaei nlylqrefek
      181 dekprdksyq davledifkk ndhdgdgfis pkeynvyqhd el
//