LOCUS       NP_776539                233 aa            linear   MAM 22-OCT-2008
DEFINITION  methionine sulfoxide reductase A [Bos taurus].
ACCESSION   NP_776539
VERSION     NP_776539.1  GI:27806537
DBSOURCE    REFSEQ: accession NM_174114.2
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (residues 1 to 233)
  AUTHORS   Sagher,D., Brunell,D., Hejtmancik,J.F., Kantorow,M., Brot,N. and
            Weissbach,H.
  TITLE     Thionein can serve as a reducing agent for the methionine sulfoxide
            reductases
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 103 (23), 8656-8661 (2006)
   PUBMED   16735467
  REMARK    GeneRIF: The results indicate that thionein (T), which is formed
            when the zinc is removed from zinc-containing metallothionein
            (Zn-MT), can function as a reducing system for the Msr proteins
            because of its high content of cysteine residues.
REFERENCE   2  (residues 1 to 233)
  AUTHORS   Harhay,G.P., Sonstegard,T.S., Keele,J.W., Heaton,M.P.,
            Clawson,M.L., Snelling,W.M., Wiedmann,R.T., Van Tassell,C.P. and
            Smith,T.P.
  TITLE     Characterization of 954 bovine full-CDS cDNA sequences
  JOURNAL   BMC Genomics 6, 166 (2005)
   PUBMED   16305752
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 233)
  AUTHORS   Sonstegard,T.S., Capuco,A.V., White,J., Van Tassell,C.P.,
            Connor,E.E., Cho,J., Sultana,R., Shade,L., Wray,J.E., Wells,K.D.
            and Quackenbush,J.
  TITLE     Analysis of bovine mammary gland EST and functional annotation of
            the Bos taurus gene index
  JOURNAL   Mamm. Genome 13 (7), 373-379 (2002)
   PUBMED   12140684
REFERENCE   4  (residues 1 to 233)
  AUTHORS   Lowther,W.T., Brot,N., Weissbach,H. and Matthews,B.W.
  TITLE     Structure and mechanism of peptide methionine sulfoxide reductase,
            an 'anti-oxidation' enzyme
  JOURNAL   Biochemistry 39 (44), 13307-13312 (2000)
   PUBMED   11063566
REFERENCE   5  (residues 1 to 233)
  AUTHORS   Moskovitz,J., Weissbach,H. and Brot,N.
  TITLE     Cloning the expression of a mammalian gene involved in the
            reduction of methionine sulfoxide residues in proteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 93 (5), 2095-2099 (1996)
   PUBMED   8700890
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U37150.1.
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="8"
                     /map="8"
     Protein         1..233
                     /product="methionine sulfoxide reductase A"
                     /EC_number="1.8.4.11"
                     /function="reduction of methionine sulfoxide in proteins"
                     /calculated_mol_wt=25715
     CDS             1..233
                     /gene="MSRA"
                     /coded_by="NM_174114.2:65..766"
                     /db_xref="GeneID:281312"
ORIGIN      
        1 mlsvtrralq lfhslfpipr mgdsaakivs pqealpgrke plvvaakhhv ngnrtvepfp
       61 egtqmavfgm gcfwgaerkf wtlkgvystq vgfaggytpn ptykevcsgk tghaevvrvv
      121 fqpehisfee llkvfwenhd ptqgmrqgnd hgsqyrsaiy ptsaehvgaa lkskedyqkv
      181 lsehgfglit tdiregqtfy yaedyhqqyl skdpdgycgl ggtgvscplg ikk
//