LOCUS       NP_776373                972 aa            linear   MAM 24-OCT-2008
DEFINITION  peptidylglycine alpha-amidating monooxygenase [Bos taurus].
ACCESSION   NP_776373
VERSION     NP_776373.1  GI:27806825
DBSOURCE    REFSEQ: accession NM_173948.2
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (residues 1 to 972)
  AUTHORS   Katopodis,A.G., Ping,D.S., Smith,C.E. and May,S.W.
  TITLE     Functional and structural characterization of
            peptidylamidoglycolate lyase, the enzyme catalyzing the second step
            in peptide amidation
  JOURNAL   Biochemistry 30 (25), 6189-6194 (1991)
   PUBMED   2059626
REFERENCE   2  (residues 1 to 972)
  AUTHORS   Eipper,B.A., Park,L.P., Dickerson,I.M., Keutmann,H.T., Thiele,E.A.,
            Rodriguez,H., Schofield,P.R. and Mains,R.E.
  TITLE     Structure of the precursor to an enzyme mediating COOH-terminal
            amidation in peptide biosynthesis
  JOURNAL   Mol. Endocrinol. 1 (11), 777-790 (1987)
   PUBMED   3153462
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M18683.1.
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="7"
                     /map="7"
     Protein         1..972
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /EC_number="1.14.17.3"
                     /EC_number="4.3.2.5"
     sig_peptide     1..20
                     /note="PAM signal peptide"
                     /calculated_mol_wt=2080
     mat_peptide     31..972
                     /product="PAM"
                     /calculated_mol_wt=104897
     CDS             1..972
                     /gene="PAM"
                     /gene_synonym="MGC137729"
                     /coded_by="NM_173948.2:134..3052"
                     /db_xref="GeneID:280890"
ORIGIN      
        1 magfrsllvl llvfpsgcvg frsplsvfkr fkettrsfsn eclgttrpvi pidssdfald
       61 irmpgvtpkq sdtyfcmsvr lpmdeeafvi dfkprasmdt vhhmllfgcn mpastgnywf
      121 cdegtctdka nilyawarna pptrlpkgvg frvggetgsk yfvlqvhygd isafrdnhkd
      181 csgvslhltr lpqpliagmy lmmsvdtvip pggkvvnsdi schykkypmh vfayrvhthh
      241 lgkvvsgyrv rngqwtligr qspqlpqafy pvehpvdvsf gdilaarcvf tgegrtevth
      301 iggtssdemc nlyimyymea khavsfmtct qnvapdifrt ippeanipip vksdmvmmhg
      361 hhketenkdk tsllqqpkre eegvleqgdf ysllskllge redvvhvhky nptekaeses
      421 dlvaeianvv qkkdlgrsdt resaeqergn ailvrdrihk fhrlvstlrp aesrvlslqq
      481 plpgegtwep ehtgdfhvee aldwpgvyll pgqvsgvald pqnnlvifhr gdhvwdgnsf
      541 dskfvyqqrg lgpieedtil vidpnnaavl qssgknlfyl phglsidkdg nywvtdvalh
      601 qvfkldpksk egplltlgrs mqpgsdqnhf cqptdvavdp dtgtiyvsdg ycnsrlvqfs
      661 psgkfitqwg easlesspkp gqfrvphsla lvpplgqlcv adrengriqc fktdtkefvr
      721 eikhpsfgrn vfaisyipgl lfavngkpyf edqepvqgfv mnfssgeiid vfkpvrkhfd
      781 mphdiaased gtvyvgdaht ntvwkftste kmehrsvkka gievqeikes eavvetkmen
      841 kpasselqki qekqklvkep gsgvpavlit tllvipvvvl laialfirwk ksrafgdser
      901 kleassgrvl grlrgkgggg lnlgnffasr kgysrkgfdr lstegsdqek dedaseseee
      961 ysapppapap ss
//