LOCUS       NP_577748               1266 aa            linear   BCT 23-JUL-2008
DEFINITION  DNA polymerase II large subunit [Pyrococcus furiosus DSM 3638].
ACCESSION   NP_577748
VERSION     NP_577748.2  GI:33359447
DBSOURCE    REFSEQ: accession NC_003413.1
KEYWORDS    .
SOURCE      Pyrococcus furiosus DSM 3638
  ORGANISM  Pyrococcus furiosus DSM 3638
            Archaea; Euryarchaeota; Thermococci; Thermococcales;
            Thermococcaceae; Pyrococcus.
REFERENCE   1  (residues 1 to 1266)
  AUTHORS   Robb,F.T., Maeder,D.L., Brown,J.R., DiRuggiero,J., Stump,M.D.,
            Yeh,R.K., Weiss,R.B. and Dunn,D.M.
  TITLE     Genomic sequence of hyperthermophile, Pyrococcus furiosus:
            implications for physiology and enzymology
  JOURNAL   Meth. Enzymol. 330, 134-157 (2001)
   PUBMED   11210495
REFERENCE   2  (residues 1 to 1266)
  AUTHORS   Diruggiero,J., Dunn,D., Maeder,D.L., Holley-Shanks,R., Chatard,J.,
            Horlacher,R., Robb,F.T., Boos,W. and Weiss,R.B.
  TITLE     Evidence of recent lateral gene transfer among hyperthermophilic
            archaea
  JOURNAL   Mol. Microbiol. 38 (4), 684-693 (2000)
   PUBMED   11115105
REFERENCE   3  (residues 1 to 1266)
  AUTHORS   Maeder,D.L., Weiss,R.B., Dunn,D.M., Cherry,J.L., Gonzalez,J.M.,
            DiRuggiero,J. and Robb,F.T.
  TITLE     Divergence of the hyperthermophilic archaea Pyrococcus furiosus and
            P. horikoshii inferred from complete genomic sequences
  JOURNAL   Genetics 152 (4), 1299-1305 (1999)
   PUBMED   10430560
REFERENCE   4  (residues 1 to 1266)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-FEB-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 1266)
  AUTHORS   Weiss,R.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2002) Human Genetics, University of Utah, 20
            South 2030 East, Salt Lake City, UT 84112, USA
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AAL80143.
            On Jul 31, 2003 this sequence version replaced gi:18976391.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Pyrococcus furiosus DSM 3638"
                     /strain="DSM 3638"
                     /db_xref="taxon:186497"
     Protein         1..1266
                     /product="DNA polymerase II large subunit"
                     /EC_number="2.7.7.7"
                     /calculated_mol_wt=143382
     CDS             1..1266
                     /locus_tag="PF0019"
                     /coded_by="NC_003413.1:19330..23130"
                     /note="unique DNA polymerase that is similar to eukaryotic
                     polymerases; forms a heterodimer of the small and large
                     subunits; possesses polymerization and 3' to 5'
                     exonuclease activities"
                     /transl_table=11
                     /db_xref="GeneID:1467847"
ORIGIN      
        1 mvlmelpkei eeyfemlqre idkayeiakk arsqgkdpst dveipqatdm agrveslvgp
       61 pgvaqrirel lkeydkeiva lkivdeiieg kfgdfgskek yaeqavrtal ailtegivsa
      121 plegiadvki krntwadnse ylalyyagpi rssggtaqal svlvgdyvrr klgldrfkps
      181 gkhiermvee vdlyhravsr lqyhpspdev rlamrnipie itgeatddve vshrdvegve
      241 tnqlrggail vlaegvlqka kklvkyidkm gidgwewlke fveakekgee ieeseskaee
      301 skvetrveve kgfyyklyek fraeiapsek yakeiiggrp lfagpsengg frlrygrsrv
      361 sgfatwsinp atmvlvdefl aigtqmkter pgkgavvtpa ttaegpivkl kdgsvvrvdd
      421 ynlalkirde veeilylgda iiafgdfven nqtllpanyv eewwiqefvk avneayevel
      481 rpfeenpres veeaaeylev dpeflakmly dplrvkppve laihfseile iplhpyytly
      541 wntvnpkdve rlwgvlkdka tiewgtfrgi kfakkieisl ddlgslkrtl ellglphtvr
      601 egivvvdypw saalltplgn lewefkakpf ytvidiinen nqiklrdrgi swigarmgrp
      661 ekakerkmkp pvqvlfpigl aggssrdikk aaeegkiaev eiaffkcpkc ghvgpetlcp
      721 ecgirkeliw tcpkcgaeyt nsqaegysys cpkcnvklkp ftkrkikpse llnramenvk
      781 vygvdklkgv mgmtsgwkia eplekgllra knevyvfkdg tirfdatdap ithfrpreig
      841 vsveklrelg ythdfegkpl vsedqivelk pqdvilskea gkyllrvarf vddllekfyg
      901 lprfynaekm edlighlvig laphtsagiv griigfvdal vgyahpyfha akrrncdgde
      961 dsvmllldal lnfsryylpe krggkmdapl vittrldpre vdsevhnmdv vryyplefye
     1021 atyelkspke lvgvierved rlgkpemyyg ikfthdtddi algpkmslyk qlgdmeekvk
     1081 rqltlaerir avdqhyvaet ilnshlipdl rgnlrsftrq efrcvkcntk yrrppldgkc
     1141 pvcggkivlt vskgaiekyl gtakmlvany nvkpytrqri cltekdidsl feylfpeaql
     1201 tlivdpndic mkmikertge tvqggllenf nssgnngkki ekkekkakek pkkkkvisld
     1261 dffskr
//