LOCUS       NP_539541                339 aa            linear   BCT 21-JUL-2008
DEFINITION  ketol-acid reductoisomerase [Brucella melitensis 16M].
ACCESSION   NP_539541
VERSION     NP_539541.1  GI:17986907
DBSOURCE    REFSEQ: accession NC_003317.1
KEYWORDS    .
SOURCE      Brucella melitensis 16M
  ORGANISM  Brucella melitensis 16M
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
            Brucellaceae; Brucella.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Paulsen,I.T., Seshadri,R., Nelson,K.E., Eisen,J.A.,
            Heidelberg,J.F., Read,T.D., Dodson,R.J., Umayam,L., Brinkac,L.M.,
            Beanan,M.J., Daugherty,S.C., Deboy,R.T., Durkin,A.S., Kolonay,J.F.,
            Madupu,R., Nelson,W.C., Ayodeji,B., Kraul,M., Shetty,J., Malek,J.,
            Van Aken,S.E., Riedmuller,S., Tettelin,H., Gill,S.R., White,O.,
            Salzberg,S.L., Hoover,D.L., Lindler,L.E., Halling,S.M., Boyle,S.M.
            and Fraser,C.M.
  TITLE     The Brucella suis genome reveals fundamental similarities between
            animal and plant pathogens and symbionts
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (20), 13148-13153 (2002)
   PUBMED   12271122
REFERENCE   2  (residues 1 to 339)
  AUTHORS   DelVecchio,V.G., Kapatral,V., Redkar,R.J., Patra,G., Mujer,C.,
            Los,T., Ivanova,N., Anderson,I., Bhattacharyya,A., Lykidis,A.,
            Reznik,G., Jablonski,L., Larsen,N., D'Souza,M., Bernal,A.,
            Mazur,M., Goltsman,E., Selkov,E., Elzer,P.H., Hagius,S.,
            O'Callaghan,D., Letesson,J.-J., Haselkorn,R., Kyrpides,N. and
            Overbeek,R.
  TITLE     The genome sequence of the facultative intracellular pathogen
            Brucella melitensis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (1), 443-448 (2002)
   PUBMED   11756688
REFERENCE   3  (residues 1 to 339)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (residues 1 to 339)
  AUTHORS   Kapatral,V., Los,T., Ivanova,N., Anderson,I., Bhattacharyya,A.,
            Lykidis,A., Reznik,G., Jablonski,L., Larsen,N., D'Souza,M.,
            Bernal,A., Mazur,M., Goltsman,E., Selkov,E., Haselkorn,R.,
            Kyrpides,N. and Overbeek,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2001) Integrated Genomics, Inc., 2201 W. Campbell
            Park Drive, IL 60612, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAL51805.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Brucella melitensis 16M"
                     /strain="16M"
                     /db_xref="taxon:224914"
                     /chromosome="I"
     Protein         1..339
                     /product="ketol-acid reductoisomerase"
                     /EC_number="1.1.1.86"
                     /calculated_mol_wt=36949
     CDS             1..339
                     /locus_tag="BMEI0624"
                     /coded_by="NC_003317.1:651728..652747"
                     /note="catalyzes the formation of
                     (R)-2,3-dihydroxy-3-methylbutanoate from
                     (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and
                     isoleucine biosynthesis"
                     /transl_table=11
                     /db_xref="GeneID:1196335"
ORIGIN      
        1 mrvyydrdad vnlikskkvv ivgygsqgra halnlkdsga anvrvalreg satvqkaqad
       61 gfevmnvada akwadlmmma tpdelqadiy rdhihnnlrd gaaiafahgl nvhcgliepk
      121 ktvdvmmiap kgpghtvrge yqkgggvpcl iaihqdasgn ahdlalsyas gvgggrsgvi
      181 ettfkeecet dlfgeqavlc ggvvelirtg fevlveagya pemayfecln emklivdliy
      241 eggianmnys isntaewgey vtgpriitae tkaemkrvlk diqtgkftsd wmqewkagaa
      301 rfkgirrlnd ahqieevggk lrammpwiek nklvdkarn
//