LOCUS       NP_439514                474 aa            linear   BCT 18-JUL-2008
DEFINITION  pyridine nucleotide transhydrogenase [Haemophilus influenzae Rd
            KW20].
ACCESSION   NP_439514
VERSION     NP_439514.1  GI:16273273
DBSOURCE    REFSEQ: accession NC_000907.1
KEYWORDS    .
SOURCE      Haemophilus influenzae Rd KW20
  ORGANISM  Haemophilus influenzae Rd KW20
            Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
            Pasteurellaceae; Haemophilus.
REFERENCE   1  (residues 1 to 474)
  AUTHORS   Langen,H., Takacs,B., Evers,S., Berndt,P., Lahm,H.W., Wipf,B.,
            Gray,C. and Fountoulakis,M.
  TITLE     Two-dimensional map of the proteome of Haemophilus influenzae
  JOURNAL   Electrophoresis 21 (2), 411-429 (2000)
   PUBMED   10675023
REFERENCE   2  (residues 1 to 474)
  AUTHORS   Fountoulakis,M., Juranville,J.F., Roder,D., Evers,S., Berndt,P. and
            Langen,H.
  TITLE     Reference map of the low molecular mass proteins of Haemophilus
            influenzae
  JOURNAL   Electrophoresis 19 (10), 1819-1827 (1998)
   PUBMED   9719565
REFERENCE   3  (residues 1 to 474)
  AUTHORS   Tatusov,R.L., Mushegian,A.R., Bork,P., Brown,N.P., Hayes,W.S.,
            Borodovsky,M., Rudd,K.E. and Koonin,E.V.
  TITLE     Metabolism and evolution of Haemophilus influenzae deduced from a
            whole-genome comparison with Escherichia coli
  JOURNAL   Curr. Biol. 6 (3), 279-291 (1996)
   PUBMED   8805245
REFERENCE   4  (residues 1 to 474)
  AUTHORS   Smith,H.O., Tomb,J.F., Dougherty,B.A., Fleischmann,R.D. and
            Venter,J.C.
  TITLE     Frequency and distribution of DNA uptake signal sequences in the
            Haemophilus influenzae Rd genome
  JOURNAL   Science 269 (5223), 538-540 (1995)
   PUBMED   7542802
REFERENCE   5  (residues 1 to 474)
  AUTHORS   Fleischmann,R.D., Adams,M.D., White,O., Clayton,R.A.,
            Kirkness,E.F., Kerlavage,A.R., Bult,C.J., Tomb,J.-F.,
            Dougherty,B.A., Merrick,J.M., McKenney,K., Sutton,G.G.,
            FitzHugh,W., Fields,C.A., Gocayne,J.D., Scott,J.D., Shirley,R.,
            Liu,L.I., Glodek,A., Kelley,J.M., Weidman,J.F., Phillips,C.A.,
            Spriggs,T., Hedblom,E., Cotton,M.D., Utterback,T., Hanna,M.C.,
            Nguyen,D.T., Saudek,D.M., Brandon,R.C., Fine,L.D., Fritchman,J.L.,
            Fuhrmann,J.L., Geoghagen,N.S., Gnehm,C.L., McDonald,L.A.,
            Small,K.V., Fraser,C.M., Smith,H.O. and Venter,J.C.
  TITLE     Whole-genome random sequencing and assembly of Haemophilus
            influenzae Rd
  JOURNAL   Science 269 (5223), 496-512 (1995)
   PUBMED   7542800
REFERENCE   6  (residues 1 to 474)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   7  (residues 1 to 474)
  CONSRTM   NCBI Microbial Genomes Annotation Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAC23010.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Haemophilus influenzae Rd KW20"
                     /db_xref="taxon:71421"
     Protein         1..474
                     /product="pyridine nucleotide transhydrogenase"
                     /EC_number="1.6.1.2"
                     /calculated_mol_wt=50032
     CDS             1..474
                     /gene="pntB"
                     /locus_tag="HI1363"
                     /coded_by="NC_000907.1:1448434..1449858"
                     /note="catalyzes reversible transfer of hydride ion
                     equivalent between NAD and NADP; membrane-bound proton
                     pump that translocates protons from cytosolic to
                     periplasmic side of the inner membrane; forms a tetramer
                     composed of two alpha and 2 beta subunits;
                     AB-stereospecific enzyme"
                     /transl_table=11
                     /db_xref="GeneID:950280"
ORIGIN      
        1 mseglvqaay ilaallfims laglskheta kagcwfgivg mtialiatif gphsegtfwi
       61 iiamiiggai gvqralkvem tempelvail hsfvglaavl vgfnsyglhh ealmpeglda
      121 aaqaafvaeq avltnihnve vflgifigav tftgsvvafg klsgkinska lmlphrhkln
      181 laalvvsall mvaflnnpes ifpvllmtai alafgwhlva siggadmpvv vsmlnsysgw
      241 aaaaagfiln ndllivtgal vgssgailsy imckamnrsf vsviaggfgn dvqvssseeq
      301 gehrettaee vaellknass viitpgygma vaqaqypvad itaklrergv nvrfgihpva
      361 grlpghmnvl laeakvpydv vlemdeindd fadtdvvlvi gandtvnpaa medpnspiag
      421 mpvlevwkaq nvivfkrsma vgyagvqnpl ffkentqmlf gdakdrvedi lkal
//