LOCUS NP_415580 348 aa linear BCT 17-MAY-2008
DEFINITION dihydro-orotase [Escherichia coli str. K-12 substr. MG1655].
ACCESSION NP_415580
VERSION NP_415580.1 GI:16129025
DBSOURCE REFSEQ: accession NC_000913.2
KEYWORDS .
SOURCE Escherichia coli str. K12 substr. MG1655
ORGANISM Escherichia coli str. K12 substr. MG1655
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
Enterobacteriaceae; Escherichia.
REFERENCE 1 (residues 1 to 348)
AUTHORS Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R.,
Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T.,
Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H.,
Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L.
TITLE Escherichia coli K-12: a cooperatively developed annotation
snapshot--2005
JOURNAL Nucleic Acids Res. 34 (1), 1-9 (2006)
PUBMED 16397293
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 348)
AUTHORS Blattner,F.R., Plunkett,G., Bloch,C.A., Perna,N.T., Burland,V.,
Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F.,
Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J.,
Mau,B. and Shao,Y.
TITLE The complete genome sequence of Escherichia coli K-12
JOURNAL Science 277 (5331), 1453-1474 (1997)
PUBMED 9278503
REFERENCE 3 (residues 1 to 348)
AUTHORS Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y.,
Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T.,
Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and
Wanner,B.L.
TITLE Workshop on Annotation of Escherichia coli K-12
JOURNAL Unpublished
REMARK Woods Hole, Mass., on 14-18 November 2003 (sequence corrections)
REFERENCE 4 (residues 1 to 348)
AUTHORS Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D.,
Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H.
TITLE ASAP: Escherichia coli K-12 strain MG1655 version m56
JOURNAL Unpublished
REMARK ASAP download 10 June 2004 (annotation updates)
REFERENCE 5 (residues 1 to 348)
AUTHORS Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T.
TITLE A more accurate sequence comparison between genomes of Escherichia
coli K12 W3110 and MG1655 strains
JOURNAL Unpublished
REMARK GenBank accessions AG613214 to AG613378 (sequence corrections)
REFERENCE 6 (residues 1 to 348)
AUTHORS Perna,N.T.
TITLE Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic
sequence correction
JOURNAL Unpublished
REMARK GenBank accession AY605712 (sequence corrections)
REFERENCE 7 (residues 1 to 348)
AUTHORS Rudd,K.E.
TITLE A manual approach to accurate translation start site annotation: an
E. coli K-12 case study
JOURNAL Unpublished
REFERENCE 8 (residues 1 to 348)
AUTHORS Rudd,K.E.
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2008) Department of Biochemistry and Molecular
Biology, University of Miami Miller School of Medicine, 118 Gautier
Bldg., Miami, FL 33136, USA
REMARK Annotation update from ecogene.org as a multi-database
collaboration
REFERENCE 9 (residues 1 to 348)
AUTHORS Rudd,K.E.
TITLE Direct Submission
JOURNAL Submitted (26-SEP-2007) Department of Biochemistry and Molecular
Biology, University of Miami Miller School of Medicine, 118 Gautier
Bldg., Miami, FL 33136, USA
REMARK Annotation update from ecogene.org as a multi-database
collaboration
REFERENCE 10 (residues 1 to 348)
AUTHORS Rudd,K.E.
TITLE Direct Submission
JOURNAL Submitted (24-APR-2007) Department of Biochemistry and Molecular
Biology, University of Miami Miller School of Medicine, 118 Gautier
Bldg., Miami, FL 33136, USA
REMARK Annotation update from ecogene.org as a multi-database
collaboration
REFERENCE 11 (residues 1 to 348)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (07-FEB-2006) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REMARK Protein updates by submitter
REFERENCE 12 (residues 1 to 348)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-2004) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REMARK Sequence update by submitter
REFERENCE 13 (residues 1 to 348)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (13-OCT-1998) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE 14 (residues 1 to 348)
AUTHORS Blattner,F.R. and Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (02-SEP-1997) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE 15 (residues 1 to 348)
AUTHORS Blattner,F.R. and Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (16-JAN-1997) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AAC74146.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..348
/organism="Escherichia coli str. K12 substr. MG1655"
/strain="K-12"
/sub_strain="MG1655"
/db_xref="taxon:511145"
Protein 1..348
/product="dihydro-orotase"
/EC_number="3.5.2.3"
/function="enzyme; Pyrimidine ribonucleotide biosynthesis"
/calculated_mol_wt=38696
mat_peptide 2..348
/product="dihydro-orotase"
/experiment="N-terminus verified by Edman degradation:
PMID 9298646"
/calculated_mol_wt=38696
CDS 1..348
/gene="pyrC"
/locus_tag="b1062"
/gene_synonym="ECK1047"
/gene_synonym="JW1049"
/coded_by="complement(NC_000913.2:1120784..1121830)"
/GO_component="cytoplasm"
/GO_process="pyrimidine nucleotide biosynthetic process"
/transl_table=11
/db_xref="ASAP:ABE-0003607"
/db_xref="UniProtKB/Swiss-Prot:P05020"
/db_xref="ECOCYC:EG10806"
/db_xref="EcoGene:EG10806"
/db_xref="GeneID:945787"
ORIGIN
1 mtapsqvlki rrpddwhlhl rdgdmlktvv pytseiygra ivmpnlappv ttveaavayr
61 qrildavpag hdftplmtcy ltdsldpnel ergfnegvft aaklypanat tnsshgvtsi
121 daimpvlerm ekigmpllvh gevthadidi fdrearfies vmeplrqrlt alkvvfehit
181 tkdaadyvrd gnerlaatit pqhlmfnrnh mlvggvrphl yclpilkrni hqqalrelva
241 sgfnrvflgt dsapharhrk esscgcagcf naptalgsya tvfeemnalq hfeafcsvng
301 pqfyglpvnd tfielvreeq qvaesialtd dtlvpflage tvrwsvkq
//