LOCUS       NP_390695                455 aa            linear   BCT 14-NOV-2008
DEFINITION  glutamyl-tRNA reductase [Bacillus subtilis subsp. subtilis str.
            168].
ACCESSION   NP_390695
VERSION     NP_390695.1  GI:16079869
DBSOURCE    REFSEQ: accession NC_000964.2
KEYWORDS    complete genome.
SOURCE      Bacillus subtilis subsp. subtilis str. 168
  ORGANISM  Bacillus subtilis subsp. subtilis str. 168
            Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G.,
            Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S.,
            Borriss,R., Boursier,L., Brans,A., Braun,M., Brignell,S.C.,
            Bron,S., Brouillet,S., Bruschi,C.V., Caldwell,B., Capuano,V.,
            Carter,N.M., Choi,S.K., Codani,J.J., Connerton,I.F., Cummings,N.J.,
            Daniel,R.A., Denizot,F., Devine,K.M., Dusterhoft,A., Ehrlich,S.D.,
            Emmerson,P.T., Entian,K.D., Errington,J., Fabret,C., Ferrari,E.,
            Foulger,D., Fritz,C., Fujita,M., Fujita,Y., Fuma,S., Galizzi,A.,
            Galleron,N., Ghim,S.Y., Glaser,P., Goffeau,A., Golightly,E.J.,
            Grandi,G., Guiseppi,G., Guy,B.J., Haga,K., Haiech,J., Harwood,C.R.,
            Henaut,A., Hilbert,H., Holsappel,S., Hosono,S., Hullo,M.F.,
            Itaya,M., Jones,L., Joris,B., Karamata,D., Kasahara,Y.,
            Klaerr-Blanchard,M., Klein,C., Kobayashi,Y., Koetter,P.,
            Koningstein,G., Krogh,S., Kumano,M., Kurita,K., Lapidus,A.,
            Lardinois,S., Lauber,J., Lazarevic,V., Lee,S.M., Levine,A., Liu,H.,
            Masuda,S., Mauel,C., Medigue,C., Medina,N., Mellado,R.P.,
            Mizuno,M., Moestl,D., Nakai,S., Noback,M., Noone,D., O'Reilly,M.,
            Ogawa,K., Ogiwara,A., Oudega,B., Park,S.H., Parro,V., Pohl,T.M.,
            Portetelle,D., Porwollik,S., Prescott,A.M., Presecan,E., Pujic,P.,
            Purnelle,B., Rapoport,G., Rey,M., Reynolds,S., Rieger,M.,
            Rivolta,C., Rocha,E., Roche,B., Rose,M., Sadaie,Y., Sato,T.,
            Scanlan,E., Schleich,S., Schroeter,R., Scoffone,F., Sekiguchi,J.,
            Sekowska,A., Seror,S.J., Serror,P., Shin,B.S., Soldo,B.,
            Sorokin,A., Tacconi,E., Takagi,T., Takahashi,H., Takemaru,K.,
            Takeuchi,M., Tamakoshi,A., Tanaka,T., Terpstra,P., Tognoni,A.,
            Tosato,V., Uchiyama,S., Vandenbol,M., Vannier,F., Vassarotti,A.,
            Viari,A., Wambutt,R., Wedler,E., Wedler,H., Weitzenegger,T.,
            Winters,P., Wipat,A., Yamamoto,H., Yamane,K., Yasumoto,K., Yata,K.,
            Yoshida,K., Yoshikawa,H.F., Zumstein,E., Yoshikawa,H. and
            Danchin,A.
  TITLE     The complete genome sequence of the gram-positive bacterium
            Bacillus subtilis
  JOURNAL   Nature 390 (6657), 249-256 (1997)
   PUBMED   9384377
REFERENCE   2  (residues 1 to 455)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 455)
  AUTHORS   Kunst,F., Ogasawara,N., Yoshikawa,H. and Danchin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-1997) Institut Pasteur, Regulation de
            l'Expression Genetique, 28 rue du Docteur Roux, Paris Cedex 15
            75724, France
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAB14777.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Bacillus subtilis subsp. subtilis str. 168"
                     /strain="168"
                     /db_xref="taxon:224308"
     Protein         1..455
                     /product="glutamyl-tRNA reductase"
                     /EC_number="1.2.1.-"
                     /function="porphyrin biosynthesis"
                     /calculated_mol_wt=50713
     CDS             1..455
                     /gene="hemA"
                     /locus_tag="BSU28170"
                     /coded_by="complement(NC_000964.2:2876831..2878198)"
                     /note="catalyzes the formation of glutamate-1-semialdehyde
                     from glutamyl-tRNA(Glu) and NADPH; the second step of the
                     pathway is catalyzed by glutamate-1-semialdehyde
                     aminomutase which results in the formation of
                     5-aminolevulinic acid; functions in porphyrin
                     (tetrapyrroles) biosynthesis; the crystal structure showed
                     a C-terminal dimerization domain that appears to be absent
                     in Chlamydial proteins"
                     /transl_table=11
                     /db_xref="GOA:P16618"
                     /db_xref="UniProtKB/Swiss-Prot:P16618"
                     /db_xref="GeneID:937443"
ORIGIN      
        1 mhilvvgvdy ksapieirek vsfqpnelae amvqlkeeks ileniivstc nrteiyavvd
       61 qlhtgryyik kfladwfqls keelspfltf yesdaavehl frvacgldsm vigetqilgq
      121 vrdsfktaqq ektigtifne lfkqavtvgk rthaetdigs navsvsyaav elakkifgnl
      181 sskhililga gkmgelaaen lhgqgigkvt vinrtylkak eladrfsgea rslnqlesal
      241 aeadilisst gasefvvske mmenanklrk grplfmvdia vprdldpaln dlegvflydi
      301 ddlegivean mkerretaek vellieetiv efkqwmntlg vvpvisalre kalaiqsetm
      361 dsierklphl strekkllnk htksiinqml rdpilkvkel aadadseekl alfmqifdie
      421 eaagrqmmkt vessqkvhsf kkaeskagfs plvse
//