LOCUS       NP_217229                468 aa            linear   BCT 19-NOV-2008
DEFINITION  soluble pyridine nucleotide transhydrogenase [Mycobacterium
            tuberculosis H37Rv].
ACCESSION   NP_217229
VERSION     NP_217229.1  GI:15609850
DBSOURCE    REFSEQ: accession NC_000962.2
KEYWORDS    complete genome.
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
            Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
            tuberculosis complex.
REFERENCE   1
  AUTHORS   Camus,J.C., Pryor,M.J., Medigue,C. and Cole,S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148 (Pt 10), 2967-2973 (2002)
   PUBMED   12368430
REFERENCE   2  (residues 1 to 468)
  AUTHORS   Cole,S.T., Brosch,R., Parkhill,J., Garnier,T., Churcher,C.,
            Harris,D., Gordon,S.V., Eiglmeier,K., Gas,S., Barry,C.E. III,
            Tekaia,F., Badcock,K., Basham,D., Brown,D., Chillingworth,T.,
            Connor,R., Davies,R., Devlin,K., Feltwell,T., Gentles,S.,
            Hamlin,N., Holroyd,S., Hornsby,T., Jagels,K., Krogh,A., McLean,J.,
            Moule,S., Murphy,L., Oliver,K., Osborne,J., Quail,M.A.,
            Rajandream,M.A., Rogers,J., Rutter,S., Seeger,K., Skelton,J.,
            Squares,R., Squares,S., Sulston,J.E., Taylor,K., Whitehead,S. and
            Barrell,B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393 (6685), 537-544 (1998)
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   3  (residues 1 to 468)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-SEP-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CAB09473.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /db_xref="taxon:83332"
     Protein         1..468
                     /product="soluble pyridine nucleotide transhydrogenase"
                     /EC_number="1.6.1.1"
                     /function="CONVERSION OF NADPH, GENERATED BY PERIPHERAL
                     CATABOLIC PATHWAYS, TO NADH, WHICH CAN ENTER THE
                     RESPIRATORY CHAIN FOR ENERGY GENERATION [CATALYTIC
                     ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH]."
                     /calculated_mol_wt=50623
     CDS             1..468
                     /gene="sthA"
                     /locus_tag="Rv2713"
                     /coded_by="NC_000962.2:3025441..3026847"
                     /note="catalyzes the conversion of NADPH to NADH"
                     /transl_table=11
                     /db_xref="GeneID:887355"
ORIGIN      
        1 mreydivvig sgpggqkaai asaklgksva ivergrmlgg vcvntgtips ktlreavlyl
       61 tgmnqrelyg asyrvkdrit padllartqh vigkevdvvr nqlmrnrvdl ivghgrfidp
      121 htilvedqar rekttvtgdy iiiatgtrpa rpsgvefdee rvldsdgild lkslpssmvv
      181 vgagvigiey asmfaalgtk vtvvekrdnm ldfcdpevve alkfhlrdla vtfrfgeevt
      241 avdvgsagtv ttlasgkqip aetvmysagr qgqtdhldlh naglevqgrg rifvddrfqt
      301 kvdhiyavgd vigfpalaat smeqgrlaay hafgeptdgi telqpigiys ipevsyvgat
      361 eveltkssip yevgvaryre largqiagds ygmlkllvst edlkllgvhi fgtsatemvh
      421 igqavmgcgg sveylvdavf nyptfseayk naaldvmnkm ralnqfrr
//