LOCUS       NP_216111                527 aa            linear   BCT 19-NOV-2008
DEFINITION  L-aspartate oxidase [Mycobacterium tuberculosis H37Rv].
ACCESSION   NP_216111
VERSION     NP_216111.1  GI:15608733
DBSOURCE    REFSEQ: accession NC_000962.2
KEYWORDS    complete genome.
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
            Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
            tuberculosis complex.
REFERENCE   1
  AUTHORS   Camus,J.C., Pryor,M.J., Medigue,C. and Cole,S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148 (Pt 10), 2967-2973 (2002)
   PUBMED   12368430
REFERENCE   2  (residues 1 to 527)
  AUTHORS   Cole,S.T., Brosch,R., Parkhill,J., Garnier,T., Churcher,C.,
            Harris,D., Gordon,S.V., Eiglmeier,K., Gas,S., Barry,C.E. III,
            Tekaia,F., Badcock,K., Basham,D., Brown,D., Chillingworth,T.,
            Connor,R., Davies,R., Devlin,K., Feltwell,T., Gentles,S.,
            Hamlin,N., Holroyd,S., Hornsby,T., Jagels,K., Krogh,A., McLean,J.,
            Moule,S., Murphy,L., Oliver,K., Osborne,J., Quail,M.A.,
            Rajandream,M.A., Rogers,J., Rutter,S., Seeger,K., Skelton,J.,
            Squares,R., Squares,S., Sulston,J.E., Taylor,K., Whitehead,S. and
            Barrell,B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393 (6685), 537-544 (1998)
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   3  (residues 1 to 527)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-SEP-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CAB09074.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /db_xref="taxon:83332"
     Protein         1..527
                     /product="L-aspartate oxidase"
                     /EC_number="1.4.3.16"
                     /function="QUINOLINATE BIOSYNTHESIS. CATALYZES THE
                     OXIDATION OF L-ASPARTATE TO IMINOASPARTATE WHICH IS
                     CONDENSED WITH DIHYDROXYACETONE PHOSPHATE TO QUINOLINATE
                     UNDER THE ACTION OF QUINOLINATE SYNTHASE A [CATALYTIC
                     ACTIVITY : L-ASPARTATE + H(2)O + O(2) = OXALOACETATE +
                     NH(3) + H(2)O(2)]"
                     /calculated_mol_wt=53654
     CDS             1..527
                     /gene="nadB"
                     /locus_tag="Rv1595"
                     /coded_by="NC_000962.2:1795805..1797388"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="catalyzes the formation of oxaloacetate from
                     L-aspartate"
                     /transl_table=11
                     /db_xref="GOA:P65499"
                     /db_xref="UniProtKB/Swiss-Prot:P65499"
                     /db_xref="GeneID:886285"
ORIGIN      
        1 magpawrdaa dvvvigtgva glaaalaadr agrsvvvlsk aaqthvtath yaqggiavvl
       61 pdnddsvdah vadtlaagag lcdpdavysi vadgyravtd lvgagarlde svpgrwaltr
      121 egghsrrriv haggdatgae vqralqdaag mldirtghva lrvlhdgtav tgllvvrpdg
      181 cgiisapsvi latgglghly sattnpagst gdgialglwa gvavsdlefi qfhptmlfag
      241 raggrrplit eairgegail vdrqgnsita gvhpmgdlap rdvvaaaida rlkatgdpcv
      301 yldargiegf asrfptvtas craagidpvr qpipvvpgah yscggivtdv ygqtellgly
      361 aagevartgl hganrlasns lleglvvggr agkaaaahaa aagrsratss atwpepisyt
      421 aldrgdlqra msrdasmyra aaglhrlcds lsgaqvrdva crrdfedval tlvaqsvtaa
      481 alartesrgc hhraeypctv peqarsivvr gaddanavcv qalvavc
//