LOCUS       NP_206872                569 aa            linear   BCT 22-SEP-2008
DEFINITION  urease subunit alpha [Helicobacter pylori 26695].
ACCESSION   NP_206872
VERSION     NP_206872.1  GI:15644702
DBSOURCE    REFSEQ: accession NC_000915.1
KEYWORDS    .
SOURCE      Helicobacter pylori 26695
  ORGANISM  Helicobacter pylori 26695
            Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
            Helicobacteraceae; Helicobacter.
REFERENCE   1  (residues 1 to 569)
  AUTHORS   Tomb,J.-F., White,O., Kerlavage,A.R., Clayton,R.A., Sutton,G.G.,
            Fleischmann,R.D., Ketchum,K.A., Klenk,H.P., Gill,S.,
            Dougherty,B.A., Nelson,K., Quackenbush,J., Zhou,L., Kirkness,E.F.,
            Peterson,S., Loftus,B., Richardson,D., Dodson,R., Khalak,H.G.,
            Glodek,A., McKenney,K., Fitzegerald,L.M., Lee,N., Adams,M.D.,
            Hickey,E.K., Berg,D.E., Gocayne,J.D., Utterback,T.R.,
            Peterson,J.D., Kelley,J.M., Karp,P.D., Smith,H.O., Fraser,C.M. and
            Venter,J.C.
  TITLE     The complete genome sequence of the gastric pathogen Helicobacter
            pylori
  JOURNAL   Nature 388 (6642), 539-547 (1997)
   PUBMED   9252185
REFERENCE   2  (residues 1 to 569)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 569)
  AUTHORS   Tomb,J.-F., White,O., Kerlavage,A.R., Clayton,R.A., Sutton,G.G.,
            Fleischmann,R.D., Ketchum,K.A., Klenk,H.P., Gill,S.,
            Dougherty,B.A., Nelson,K., Quackenbush,J., Zhou,L., Kirkness,E.F.,
            Peterson,S., Loftus,B., Richardson,D., Dodson,R., Khalak,H.G.,
            Glodek,A., McKenney,K., Fitzegerald,L.M., Lee,N., Adams,M.D.,
            Hickey,E.K., Berg,D.E., Gocayne,J.D., Utterback,T.R.,
            Peterson,J.D., Kelley,J.M., Cotton,M.D., Weidman,J.M., Fujii,C.,
            Bowman,C., Watthey,L., Wallin,E., Hayes,W.S., Borodovsky,M.,
            Karp,P.D., Smith,H.O., Fraser,C.M. and Venter,J.C.
  CONSRTM   NCBI Microbial Genomes Annotation Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-1997) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AAD07143.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Helicobacter pylori 26695"
                     /strain="26695"
                     /db_xref="taxon:85962"
     Protein         1..569
                     /product="urease subunit alpha"
                     /EC_number="3.5.1.5"
                     /calculated_mol_wt=61553
     CDS             1..569
                     /gene="ureC"
                     /locus_tag="HP0072"
                     /coded_by="complement(NC_000915.1:75527..77236)"
                     /note="ureases catalyze the hydrolysis of urea into
                     ammonia and carbon dioxide; in Helicobacter pylori the
                     ammonia released plays a key role in bacterial survival by
                     neutralizing acids when colonizing the gastric mucosa; the
                     holoenzyme is composed of 3 ureC (alpha) and 3 ureAB
                     (gamma/beta) subunits"
                     /transl_table=11
                     /db_xref="GeneID:899104"
ORIGIN      
        1 mkkisrkeyv smygpttgdk vrlgdtdlia evehdytiyg eelkfgggkt lregmsqsnn
       61 pskeeldlii tnalivdytg iykadigikd gkiagigkgg nkdmqdgvkn nlsvgpatea
      121 lageglivta ggidthihfi spqqiptafa sgvttmiggg tgpadgtnat titpgrrnlk
      181 wmlraaeeys mnlgflakgn asndasladq ieagaigfki hedwgttpsa inhaldvadk
      241 ydvqvaihtd tlneagcved tmaaiagrtm htfhtegagg ghapdiikva gehnilpast
      301 nptipftvnt eaehmdmlmv chhldksike dvqfadsrir pqtiaaedtl hdmgifsits
      361 sdsqamgrvg evitrtwqta dknkkefgrl keekgdndnf rikrylskyt inpaiahgis
      421 eyvgsvevgk vadlvlwspa ffgvkpnmii kggfialsqm gdanasiptp qpvyyremfa
      481 hhgkakydan itfvsqaayd kgikeelgle rqvlpvkncr nitkkdmqfn dttahievnp
      541 etyhvfvdgk evtskpankv slaqlfsif
//