LOCUS       NP_033480                207 aa            linear   ROD 24-OCT-2008
DEFINITION  ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog [Mus musculus].
ACCESSION   NP_033480 XP_917598 XP_927490 XP_927497
VERSION     NP_033480.1  GI:6678477
DBSOURCE    REFSEQ: accession NM_009454.2
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE   1  (residues 1 to 207)
  AUTHORS   Bedard,N., Hingamp,P., Pang,Z., Karaplis,A., Morales,C.,
            Trasler,J., Cyr,D., Gagnon,C. and Wing,S.S.
  TITLE     Mice lacking the UBC4-testis gene have a delay in postnatal testis
            development but normal spermatogenesis and fertility
  JOURNAL   Mol. Cell. Biol. 25 (15), 6346-6354 (2005)
   PUBMED   16024774
  REMARK    GeneRIF: UBC4-testis isoform plays a role in early maturation of
            the testis
REFERENCE   2  (residues 1 to 207)
  AUTHORS   Plafker,S.M., Plafker,K.S., Weissman,A.M. and Macara,I.G.
  TITLE     Ubiquitin charging of human class III ubiquitin-conjugating enzymes
            triggers their nuclear import
  JOURNAL   J. Cell Biol. 167 (4), 649-659 (2004)
   PUBMED   15545318
REFERENCE   3  (residues 1 to 207)
  AUTHORS   Debonneville,C. and Staub,O.
  TITLE     Participation of the ubiquitin-conjugating enzyme UBE2E3 in
            Nedd4-2-dependent regulation of the epithelial Na+ channel
  JOURNAL   Mol. Cell. Biol. 24 (6), 2397-2409 (2004)
   PUBMED   14993279
REFERENCE   4  (residues 1 to 207)
  AUTHORS   Plafker,S.M. and Macara,I.G.
  TITLE     Ribosomal protein L12 uses a distinct nuclear import pathway
            mediated by importin 11
  JOURNAL   Mol. Cell. Biol. 22 (4), 1266-1275 (2002)
   PUBMED   11809816
REFERENCE   5  (residues 1 to 207)
  AUTHORS   Plafker,S.M. and Macara,I.G.
  TITLE     Importin-11, a nuclear import receptor for the
            ubiquitin-conjugating enzyme, UbcM2
  JOURNAL   EMBO J. 19 (20), 5502-5513 (2000)
   PUBMED   11032817
REFERENCE   6  (residues 1 to 207)
  AUTHORS   Pestov,D.G., Grzeszkiewicz,T.M. and Lau,L.F.
  TITLE     Isolation of growth suppressors from a cDNA expression library
  JOURNAL   Oncogene 17 (24), 3187-3197 (1998)
   PUBMED   9872334
REFERENCE   7  (residues 1 to 207)
  AUTHORS   Harbers,K., Muller,U., Grams,A., Li,E., Jaenisch,R. and Franz,T.
  TITLE     Provirus integration into a gene encoding a ubiquitin-conjugating
            enzyme results in a placental defect and embryonic lethality
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 93 (22), 12412-12417 (1996)
   PUBMED   8901595
REFERENCE   8  (residues 1 to 207)
  AUTHORS   Matuschewski,K., Hauser,H.P., Treier,M. and Jentsch,S.
  TITLE     Identification of a novel family of ubiquitin-conjugating enzymes
            with distinct amino-terminal extensions
  JOURNAL   J. Biol. Chem. 271 (5), 2789-2794 (1996)
   PUBMED   8576256
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC011477.1.
            On or before Dec 7, 2005 this sequence version replaced
            gi:82884976, gi:82884978, gi:82884980.
FEATURES             Location/Qualifiers
     source          1..207
                     /organism="Mus musculus"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="2"
     Protein         1..207
                     /product="ubiquitin-conjugating enzyme E2E 3, UBC4/5
                     homolog"
                     /EC_number="6.3.2.19"
                     /note="ubiquitin-conjugating enzyme 4"
                     /calculated_mol_wt=22782
     CDS             1..207
                     /gene="Ube2e3"
                     /gene_synonym="Ubce4"
                     /gene_synonym="ubcM2"
                     /coded_by="NM_009454.2:388..1011"
                     /db_xref="CCDS:CCDS16167.1"
                     /db_xref="GeneID:22193"
                     /db_xref="MGI:107412"
ORIGIN      
        1 mssdrqrsdd espstssgss dadqrdpaap epeeqeerkp satqqkkntk lsskttakls
       61 tsakriqkel aeitldpppn csagpkgdni yewrstilgp pgsvyeggvf flditfssdy
      121 pfkppkvtfr triyhcnins qgvicldilk dnwspaltis kvllsicsll tdcnpadplv
      181 gsiatqyltn raehdriarq wtkryat
//