LOCUS       NP_001080091             486 aa            linear   VRT 24-OCT-2008
DEFINITION  thymoma viral proto-oncogene 2 [Xenopus laevis].
ACCESSION   NP_001080091
VERSION     NP_001080091.1  GI:147904856
DBSOURCE    REFSEQ: accession NM_001086622.1
KEYWORDS    .
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
            Xenopodinae; Xenopus; Xenopus.
REFERENCE   1  (residues 1 to 486)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC046261.1.
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Xenopus laevis"
                     /db_xref="taxon:8355"
     Protein         1..486
                     /product="thymoma viral proto-oncogene 2"
                     /EC_number="2.7.11.1"
                     /calculated_mol_wt=56179
     Region          6..110
                     /region_name="PH domain. PH stands for pleckstrin
                     homology"
                     /note="PH; PH domain. PH stands for pleckstrin homology"
     Region          156..414
                     /region_name="Serine/Threonine protein kinases, catalytic
                     domain. Phosphotransferases of the serine or
                     threonine-specific kinase subfamily. The enzymatic
                     activity of these protein kinases is controlled by
                     phosphorylation of specific residues in the activation
                     segment of the catalytic domain, sometimes combined with
                     reversible conformational changes in the C-terminal
                     autoregulatory tail"
                     /note="S_TKc; Serine/Threonine protein kinases, catalytic
                     domain. Phosphotransferases of the serine or
                     threonine-specific kinase subfamily. The enzymatic
                     activity of these protein kinases is controlled by
                     phosphorylation of specific residues in the activation
                     segment of the catalytic domain, sometimes combined with
                     reversible conformational changes in the C-terminal
                     autoregulatory tail"
     Region          416..482
                     /region_name="Extension to Ser/Thr-type protein kinases"
                     /note="S_TK_X; Extension to Ser/Thr-type protein kinases"
     CDS             1..486
                     /gene="akt2"
                     /gene_synonym="MGC53299"
                     /coded_by="NM_001086622.1:158..1618"
                     /db_xref="GeneID:379783"
ORIGIN      
        1 mnevmvikeg wlqkrgeyik twrpryfllk sdgsfigyke kpestehnvv lpplnnfsva
       61 ecqlmkterp rpntfvircl qwttviertf hvdtpeeree wiiaiqtvan glknqvpede
      121 eeeamevkyg spsdvssaeq mdvamskghp kvtmndfdyl kllgkgtfgk vilvrekatg
      181 ryyamkilrk eviiakdeva htltesrvlq ntkhpfltal kyafqtsdrl cfvmeyangg
      241 elffhlsrer vftedrarfy gaeivsaley lhsrnvvyrd iklenlmldk dghvkitdfg
      301 lckegitdga tmrtfcgtpe ylapevledn dygravdwwg lgvvmyemmc grlpfynqdh
      361 erlfelilme eirfprtlsp eaksllagll kkdpkqrlgg gpndaqevms hrffvsinwq
      421 dvterkltpp fkpqvtseid tryfddefta qsitltppdr ydnldalesd qrphfpqfsy
      481 sasire
//