LOCUS       NP_001073808             147 aa            linear   MAM 22-OCT-2008
DEFINITION  lysozyme [Bos taurus].
ACCESSION   NP_001073808 XP_001249626
VERSION     NP_001073808.1  GI:122692317
DBSOURCE    REFSEQ: accession NM_001080339.1
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (residues 1 to 147)
  AUTHORS   Irwin,D.M., White,R.T. and Wilson,A.C.
  TITLE     Characterization of the cow stomach lysozyme genes: repetitive DNA
            and concerted evolution
  JOURNAL   J. Mol. Evol. 37 (4), 355-366 (1993)
   PUBMED   8308905
REFERENCE   2  (residues 1 to 147)
  AUTHORS   Irwin,D.M. and Wilson,A.C.
  TITLE     Multiple cDNA sequences and the evolution of bovine stomach
            lysozyme
  JOURNAL   J. Biol. Chem. 264 (19), 11387-11393 (1989)
   PUBMED   2738070
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M26245.1.
            On Jan 16, 2007 this sequence version replaced gi:119892337.
FEATURES             Location/Qualifiers
     source          1..147
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="5"
                     /map="5"
     Protein         1..147
                     /product="lysozyme"
                     /EC_number="3.2.1.17"
                     /note="lysozyme protein"
     sig_peptide     1..18
                     /note="lysozyme 1a signal peptide"
                     /calculated_mol_wt=1920
     mat_peptide     19..147
                     /product="lysozyme 1a"
                     /calculated_mol_wt=14390
     Region          19..143
                     /region_name="LYZ1"
                     /note="C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ)
                     and alpha-lactalbumin (lactose synthase B protein, LA).
                     They have a close evolutionary relationship and similar
                     tertiary structure, however, functionally they are quite
                     different. Lysozymes have...; cd00119"
                     /db_xref="CDD:29018"
     Site            order(52..53,55,62,76,78,81,117,120,125..126)
                     /site_type="other"
                     /note="lysozyme catalytic cleft"
                     /db_xref="CDD:29018"
     Site            order(53,71)
                     /site_type="other"
                     /note="lysozyme catalytic site"
                     /db_xref="CDD:29018"
     Site            order(104,109..110)
                     /site_type="other"
                     /note="Ca2+ binding site"
                     /db_xref="CDD:29018"
     CDS             1..147
                     /gene="LYZ"
                     /gene_synonym="LYSOZYME"
                     /coded_by="NM_001080339.1:23..466"
                     /db_xref="GeneID:781349"
ORIGIN      
        1 mkaliilgfl flsvavqgkv fercelartl kklgldgykg vslanwlclt kwessyntka
       61 tnynpgsest dygifqinsk wwcndgktpn avdgchvscs elmeneiaka vacakqivse
      121 qgitawvawk shcrdhdvss yvegctl
//