LOCUS       NP_001068703             421 aa            linear   MAM 24-OCT-2008
DEFINITION  acyl-coenzyme A dehydrogenase, C-4 to C-12 straight chain [Bos
            taurus].
ACCESSION   NP_001068703 XP_582342
VERSION     NP_001068703.1  GI:115497690
DBSOURCE    REFSEQ: accession NM_001075235.1
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC102989.1.
            On Oct 4, 2006 this sequence version replaced gi:76678452.
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="3"
                     /map="3"
                     /breed="Hereford"
     Protein         1..421
                     /product="acyl-coenzyme A dehydrogenase, C-4 to C-12
                     straight chain"
                     /EC_number="1.3.99.3"
                     /note="C-4 to C-12 straight chain acyl-coenzyme A
                     dehydrogenase"
                     /calculated_mol_wt=46442
     Region          39..421
                     /region_name="CaiA"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism];
                     COG1960"
                     /db_xref="CDD:32143"
     Region          41..418
                     /region_name="MCAD"
                     /note="Medium chain acyl-CoA dehydrogenase (MCAD). MCADs
                     are mitochondrial beta-oxidation enzymes, which catalyze
                     the alpha,beta dehydrogenation of the corresponding medium
                     chain acyl-CoA by FAD, which becomes reduced. The reduced
                     form of MCAD is reoxidized...; cd01157"
                     /db_xref="CDD:29657"
     Site            order(41..43,103,164,191,238..241,297,300,306,309,314,
                     316..318,320..321,324..325,327,331,335..336,338..339,342,
                     352..353,370,374,381..383,392,395,398..399,408..409,412,
                     415)
                     /site_type="other"
                     /note="homotetramer interface"
                     /db_xref="CDD:29657"
     Site            order(124,128,158,160..161,166..167,191,193,270,277..278,
                     281,349,351,396,399..401,403,405)
                     /site_type="active"
                     /db_xref="CDD:29657"
     Site            401
                     /site_type="other"
                     /note="catalytic base"
                     /db_xref="CDD:29657"
     CDS             1..421
                     /gene="ACADM"
                     /gene_synonym="MGC128274"
                     /coded_by="NM_001075235.1:23..1288"
                     /db_xref="GeneID:505968"
ORIGIN      
        1 mialfrrscg vlrslshfdw rsqhtktalq repgsgfsfe fteqqkefqa tarkfareei
       61 iplaaeydkt geypvplikr awelglmnth ipescgglgl gtfdsclise elaygctgvq
      121 taieanslgq mpviiagndq qqkkylgrmt eeplmcaycv tepvagsdva giktkaekkg
      181 deyiingqkm witnggkanw yfllarsdpd pkapaskaft gfiveadtpg vqigrkelnm
      241 gqrcsdtrgi vfedvrvpke nvligegagf kiamgafdkt rppvaaaavg laqraldeat
      301 kyalerktfg klliehqgis fllaemamkv elarlsyqra awevdsgrrn tyyasiakay
      361 agdianqlas davqifggng fnteypvekl mrdakiyqiy egtaqiqrli iarehigryk
      421 k
//