LOCUS       NP_001030463             527 aa            linear   MAM 22-OCT-2008
DEFINITION  catalase [Bos taurus].
ACCESSION   NP_001030463 XP_871721
VERSION     NP_001030463.1  GI:78369302
DBSOURCE    REFSEQ: accession NM_001035386.1
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (residues 1 to 527)
  AUTHORS   Brezniceanu,M.L., Liu,F., Wei,C.C., Chenier,I., Godin,N.,
            Zhang,S.L., Filep,J.G., Ingelfinger,J.R. and Chan,J.S.
  TITLE     Attenuation of interstitial fibrosis and tubular apoptosis in db/db
            transgenic mice overexpressing catalase in renal proximal tubular
            cells
  JOURNAL   Diabetes 57 (2), 451-459 (2008)
   PUBMED   17977949
  REMARK    GeneRIF: CAT transgenic mice became obese and hyperglycemic but had
            normal blood pressure and attenuated albuminuria compared with
            diabetic mice.
REFERENCE   2  (residues 1 to 527)
  AUTHORS   Brezniceanu,M.L., Liu,F., Wei,C.C., Tran,S., Sachetelli,S.,
            Zhang,S.L., Guo,D.F., Filep,J.G., Ingelfinger,J.R. and Chan,J.S.
  TITLE     Catalase overexpression attenuates angiotensinogen expression and
            apoptosis in diabetic mice
  JOURNAL   Kidney Int. 71 (9), 912-923 (2007)
   PUBMED   17342175
  REMARK    GeneRIF: Overexpression of catalase prevents the stimulation of
            reactive oxygen species and angiotensinogen mRNA in tubules owing
            to elevated glucose or angiotensin II in transgenic diabetic mice.
REFERENCE   3  (residues 1 to 527)
  AUTHORS   Gaetani,G.F., Ferraris,A.M., Sanna,P. and Kirkman,H.N.
  TITLE     A novel NADPH:(bound) NADP+ reductase and NADH:(bound) NADP+
            transhydrogenase function in bovine liver catalase
  JOURNAL   Biochem. J. 385 (PT 3), 763-768 (2005)
   PUBMED   15456401
  REMARK    GeneRIF: study of bovine liver catalase and [14C]NADPH and
            [14C]NADH revealed that unbound NADPH or NADH are substrates for an
            internal reductase and transhydrogenase reaction respectively
REFERENCE   4  (residues 1 to 527)
  AUTHORS   Orzechowski,A., Gajkowska,B., Wojewodzka,U., Cassar-Malek,I.,
            Picard,B. and Hocquette,J.F.
  TITLE     Immunohistochemical analysis of bFGF, TGF-beta1 and catalase in
            rectus abdominis muscle from cattle foetuses at 180 and 260 days
            post-conception
  JOURNAL   Tissue Cell 34 (6), 416-426 (2002)
   PUBMED   12441094
  REMARK    GeneRIF: Immunohistochemistry in rectus abdominis muscle from
            foetuses at 180 and 260 days post-conception
REFERENCE   5  (residues 1 to 527)
  AUTHORS   Ko,T.P., Day,J., Malkin,A.J. and McPherson,A.
  TITLE     Structure of orthorhombic crystals of beef liver catalase
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 55 (PT 8), 1383-1394 (1999)
   PUBMED   10417406
REFERENCE   6  (residues 1 to 527)
  AUTHORS   Melik-Adamyan,W.R., Barynin,V.V., Vagin,A.A., Borisov,V.V.,
            Vainshtein,B.K., Fita,I., Murthy,M.R. and Rossmann,M.G.
  TITLE     Comparison of beef liver and Penicillium vitale catalases
  JOURNAL   J. Mol. Biol. 188 (1), 63-72 (1986)
   PUBMED   3712444
REFERENCE   7  (residues 1 to 527)
  AUTHORS   Schroeder,W.A., Shelton,J.R., Shelton,J.B., Robberson,B., Apell,G.,
            Fang,R.S. and Bonaventura,J.
  TITLE     The complete amino acid sequence of bovine liver catalase and the
            partial sequence of bovine erythrocyte catalase
  JOURNAL   Arch. Biochem. Biophys. 214 (1), 397-421 (1982)
   PUBMED   7082009
REFERENCE   8  (residues 1 to 527)
  AUTHORS   Murthy,M.R., Reid,T.J. III, Sicignano,A., Tanaka,N. and
            Rossmann,M.G.
  TITLE     Structure of beef liver catalase
  JOURNAL   J. Mol. Biol. 152 (2), 465-499 (1981)
   PUBMED   7328661
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC103066.1.
            On Nov 1, 2005 this sequence version replaced gi:76636236.
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="15"
                     /map="15"
                     /breed="Hereford"
     Protein         1..527
                     /product="catalase"
                     /EC_number="1.11.1.6"
                     /calculated_mol_wt=59784
     CDS             1..527
                     /gene="CAT"
                     /gene_synonym="MGC128112"
                     /coded_by="NM_001035386.1:47..1630"
                     /db_xref="GeneID:531682"
ORIGIN      
        1 madnrdpasd qmkhwkeqra aqkpdvlttg ggnpvgdkln sltvgprgpl lvqdvvftde
       61 mahfdrerip ervvhakgag afgyfevthd itryskakvf ehigkrtpia vrfstvages
      121 gsadtvrdpr gfavkfyted gnwdlvgnnt piffirdall fpsfihsqkr npqthlkdpd
      181 mvwdfwslrp eslhqvsflf sdrgipdghr hmngygshtf klvnangeav yckfhyktdq
      241 giknlsveda arlahedpdy glrdlfnaia tgnypswtly iqvmtfseae ifpfnpfdlt
      301 kvwphgdypl ipvgklvlnr npvnyfaeve qlafdpsnmp pgiepspdkm lqgrlfaypd
      361 thrhrlgpny lqipvncpyr arvanyqrdg pmcmmdnqgg apnyypnsfs apehqpsale
      421 hrthfsgdvq rfnsanddnv tqvrtfylkv lneeqrkrlc eniaghlkda qlfiqkkavk
      481 nfsdvhpeyg sriqalldky neekpknavh tyvqhgshls arekanl
//