LOCUS       NP_001013612             175 aa            linear   MAM 14-SEP-2008
DEFINITION  crystallin, gamma B [Bos taurus].
ACCESSION   NP_001013612 XP_586335
VERSION     NP_001013612.1  GI:61888870
DBSOURCE    REFSEQ: accession NM_001013594.1
KEYWORDS    .
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (residues 1 to 175)
  AUTHORS   Kundu,B., Shukla,A. and Guptasarma,P.
  TITLE     Peptide scanning-based identification of regions of gamma-II
            crystallin involved in thermal aggregation: evidence of the
            involvement of structurally analogous, helix-containing loops from
            the two double Greek key domains of the molecule
  JOURNAL   Arch. Biochem. Biophys. 410 (1), 69-75 (2003)
   PUBMED   12559977
  REMARK    GeneRIF: results suggest that two regions of gamma-B crystallin
            (residues 61-74, 145-159) play key roles in aggregative
            interactions. The regions, each containing a single-turn helix in
            the native structure, are located in structurally analogous
            positions
REFERENCE   2  (residues 1 to 175)
  AUTHORS   Palme,S., Jaenicke,R. and Slingsby,C.
  TITLE     Unusual domain pairing in a mutant of bovine lens gammaB-crystallin
  JOURNAL   J. Mol. Biol. 279 (5), 1053-1059 (1998)
   PUBMED   9642083
REFERENCE   3  (residues 1 to 175)
  AUTHORS   Palme,S., Jaenicke,R. and Slingsby,C.
  TITLE     X-ray structures of three interface mutants of gammaB-crystallin
            from bovine eye lens
  JOURNAL   Protein Sci. 7 (3), 611-618 (1998)
   PUBMED   9541393
REFERENCE   4  (residues 1 to 175)
  AUTHORS   Kumaraswamy,V.S., Lindley,P.F., Slingsby,C. and Glover,I.D.
  TITLE     An eye lens protein-water structure: 1.2 A resolution structure of
            gammaB-crystallin at 150 K
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 52 (PT 4), 611-622 (1996)
   PUBMED   15299624
REFERENCE   5  (residues 1 to 175)
  AUTHORS   Najmudin,S., Nalini,V., Driessen,H.P., Slingsby,C., Blundell,T.L.,
            Moss,D.S. and Lindley,P.F.
  TITLE     Structure of the bovine eye lens protein gammaB(gammaII)-crystallin
            at 1.47 A
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 49 (PT 2), 223-233 (1993)
   PUBMED   15299528
REFERENCE   6  (residues 1 to 175)
  AUTHORS   McDermott,M.J., Gawinowicz-Kolks,M.A., Chiesa,R. and Spector,A.
  TITLE     The disulfide content of calf gamma-crystallin
  JOURNAL   Arch. Biochem. Biophys. 262 (2), 609-619 (1988)
   PUBMED   3364984
REFERENCE   7  (residues 1 to 175)
  AUTHORS   Chiou,S.H., Azari,P. and Himmel,M.E.
  TITLE     Physicochemical characterization of gamma-crystallins from bovine
            lens--hydrodynamic and biochemical properties
  JOURNAL   J. Protein Chem. 7 (1), 67-80 (1988)
   PUBMED   3255364
REFERENCE   8  (residues 1 to 175)
  AUTHORS   Hay,R.E., Woods,W.D., Church,R.L. and Petrash,J.M.
  TITLE     cDNA clones encoding bovine gamma-crystallins
  JOURNAL   Biochem. Biophys. Res. Commun. 146 (1), 332-338 (1987)
   PUBMED   3606621
REFERENCE   9  (residues 1 to 175)
  AUTHORS   Bhat,S.P. and Spector,A.
  TITLE     Complete nucleotide sequence of a cDNA derived from calf lens
            gamma-crystallin mRNA: presence of Alu I-like DNA sequences
  JOURNAL   DNA 3 (4), 287-295 (1984)
   PUBMED   6092016
REFERENCE   10 (residues 1 to 175)
  AUTHORS   Wistow,G., Turnell,B., Summers,L., Slingsby,C., Moss,D., Miller,L.,
            Lindley,P. and Blundell,T.
  TITLE     X-ray analysis of the eye lens protein gamma-II crystallin at 1.9 A
            resolution
  JOURNAL   J. Mol. Biol. 170 (1), 175-202 (1983)
   PUBMED   6631960
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M16894.1.
            On Mar 29, 2005 this sequence version replaced gi:61819615.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the
            Entrez Gene record to access additional publications.
FEATURES             Location/Qualifiers
     source          1..175
                     /organism="Bos taurus"
                     /db_xref="taxon:9913"
                     /chromosome="2"
                     /map="2"
     Protein         1..175
                     /product="crystallin, gamma B"
                     /note="gamma-B-crystallin; gammaB-crystallin"
                     /calculated_mol_wt=20966
     CDS             1..175
                     /gene="CRYGB"
                     /coded_by="NM_001013594.1:32..559"
                     /db_xref="GeneID:281720"
ORIGIN      
        1 mgkitfyedr gfqghcyecs sdcpnlqpyf srcnsirvds gcwmlyerpn yqghqyflrr
       61 gdypdyqqwm gfndsirscr lipqhtgtfr mriyerddfr gqmseitddc pslqdrfhlt
      121 evhslnvleg swvlyempsy rgrqyllrpg eyrryldwga mnakvgslrr vmdfy
//