LOCUS       NP_001010954             373 aa            linear   MAM 24-OCT-2008
DEFINITION  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid
            delta-isomerase 1 [Canis lupus familiaris].
ACCESSION   NP_001010954 XP_540264
VERSION     NP_001010954.1  GI:58219490
DBSOURCE    REFSEQ: accession NM_001010954.1
KEYWORDS    .
SOURCE      Canis lupus familiaris (dog)
  ORGANISM  Canis lupus familiaris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Kowalewski,M.P., Mason,J.I., Howie,A.F., Morley,S.D., Schuler,G.
            and Hoffmann,B.
  TITLE     Characterization of the canine 3beta-hydroxysteroid dehydrogenase
            and its expression in the corpus luteum during diestrus
  JOURNAL   J. Steroid Biochem. Mol. Biol. 101 (4-5), 254-262 (2006)
   PUBMED   16979335
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY739720.1.
            On Jan 28, 2005 this sequence version replaced gi:57098883.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Canis lupus familiaris"
                     /sub_species="familiaris"
                     /db_xref="taxon:9615"
                     /chromosome="17"
                     /map="17"
     Protein         1..373
                     /product="hydroxy-delta-5-steroid dehydrogenase, 3 beta-
                     and steroid delta-isomerase 1"
                     /EC_number="1.1.1.145"
                     /EC_number="5.3.3.1"
                     /note="3-beta-hydroxysteroid dehydrogenase;
                     hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid
                     delta-isomerase 2"
                     /calculated_mol_wt=42247
     CDS             1..373
                     /gene="HSD3B1"
                     /gene_synonym="3b-HSD"
                     /gene_synonym="HSD3B2"
                     /coded_by="NM_001010954.1:127..1248"
                     /db_xref="GeneID:483146"
ORIGIN      
        1 magwsclvtg aggflgqriv hllaeekelq eiraldkafr pelleefskl qsktkltmve
       61 gdildeqclk racqgtsvvi htasvidvmn vihretimnv nlkgtqllle acaqasvpif
      121 iytstievag pnsyrdiiqn aheeehlest wsapypyskk laekavlaan gwalknggtl
      181 htcalrpmyi ygegsiflyn yiykalrnng ilthhskfsi vnpvyvgnva wahilalral
      241 qdpkkapsvq gqfyyisddt phqsyddlny nlskewgfsl dsrmslpisl eywlafllei
      301 vsfllspiyk yqppfnrhmv tlsnsiftfs ykkaqrdlgy kplfsweeak qkttewigsl
      361 vkqhketlkt kth
//