LOCUS       NP_001008888             274 aa            linear   ROD 22-OCT-2008
DEFINITION  ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
            [Rattus norvegicus].
ACCESSION   NP_001008888 XP_214457
VERSION     NP_001008888.1  GI:57114330
DBSOURCE    REFSEQ: accession NM_001008888.1
KEYWORDS    .
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 274)
  AUTHORS   He,L. and Lemasters,J.J.
  TITLE     Dephosphorylation of the Rieske iron-sulfur protein after induction
            of the mitochondrial permeability transition
  JOURNAL   Biochem. Biophys. Res. Commun. 334 (3), 829-837 (2005)
   PUBMED   16023995
  REMARK    GeneRIF: Conformational changes from phosphorylation &
            dephosphorylation of RISP may thus regulate mitochondrial
            permeability transition pore formation & conductance.
REFERENCE   2  (residues 1 to 274)
  AUTHORS   Sun,G., Kinter,M.T. and Anderson,V.E.
  TITLE     Mass spectrometric characterization of mitochondrial electron
            transport complexes: subunits of the rat heart ubiquinol-cytochrome
            c reductase
  JOURNAL   J Mass Spectrom 38 (5), 531-539 (2003)
   PUBMED   12794875
  REMARK    GeneRIF: Mass spectrometric characterization of
            ubiquinol-cytochrome c reductase; ten of the 11 polypeptides
            present in this complex were detected directly by MALDI-TOFMS
            following electroelution of the active complex
REFERENCE   3  (residues 1 to 274)
  AUTHORS   Nishikimi,M., Hosokawa,Y., Toda,H., Suzuki,H. and Ozawa,T.
  TITLE     Cloning and sequence analysis of a cDNA encoding the Rieske
            iron-sulfur protein of rat mitochondrial cytochrome bc1 complex
  JOURNAL   Biochem. Biophys. Res. Commun. 159 (1), 19-25 (1989)
   PUBMED   2538119
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085339.1.
            On Jan 6, 2005 this sequence version replaced gi:34875396.
            
            Summary: component of the ubiquinol-cytochrome c reductase complex
            (complex III or cytochrome bc1 complex); important for generating
            an electrochemical potential coupled to ATP synthesis [RGD].
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     Protein         1..274
                     /product="ubiquinol-cytochrome c reductase, Rieske
                     iron-sulfur polypeptide 1"
                     /EC_number="1.10.2.2"
                     /calculated_mol_wt=29315
     CDS             1..274
                     /gene="Uqcrfs1"
                     /gene_synonym="MGC105530"
                     /gene_synonym="LRRGT00195"
                     /coded_by="NM_001008888.1:56..880"
                     /db_xref="GeneID:291103"
                     /db_xref="RGD:628838"
ORIGIN      
        1 mlsvaarsgp fapvlsatsr gvagalrpll qsavpatsep pvldvkrpfl creslsgqaa
       61 trplvatvgl nvpasvrysh tdikvpdfsd yrraevldst ksskessear kgfsylvtat
      121 ttvgvayaak navsqfvssm sasadvlams kieiklsdip egknmafkwr gkplfvrhrt
      181 kkeidqeaav evsqlrdpqh dlervkkpew viligvcthl gcvpianagd fggyycpchg
      241 shydasgrir kgpaplnlev ptyeftsgdv vvvg
//