LOCUS       NP_001007627             300 aa            linear   ROD 24-OCT-2008
DEFINITION  geranylgeranyl diphosphate synthase 1 [Rattus norvegicus].
ACCESSION   NP_001007627 XP_214490
VERSION     NP_001007627.1  GI:56090562
DBSOURCE    REFSEQ: accession NM_001007626.2
KEYWORDS    .
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 300)
  AUTHORS   Matsumura,Y., Kidokoro,T., Miyagi,Y., Marilingaiah,N.R. and
            Sagami,H.
  TITLE     The carboxyl-terminal region of the geranylgeranyl diphosphate
            synthase is indispensable for the stabilization of the region
            involved in substrate binding and catalysis
  JOURNAL   J. Biochem. 142 (4), 533-537 (2007)
   PUBMED   17846065
  REMARK    GeneRIF: KMFTEENE fragment residing on the carboxyl-terminal
            sequence of geranylgeranyl diphosphate synthase stabilizes the
            active region involved in the substrate binding and catalysis.
REFERENCE   2  (residues 1 to 300)
  AUTHORS   Matsumura,Y., Kuzuguchi,T. and Sagami,H.
  TITLE     Relationship between intron 4b splicing of the rat geranylgeranyl
            diphosphate synthase gene and the active enzyme expression level
  JOURNAL   J. Biochem. 136 (3), 301-312 (2004)
   PUBMED   15598886
  REMARK    GeneRIF: expression level of rat active GGPS is regulated through
            the splicing of intron 4b of its gene
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090327.1.
            On Nov 29, 2004 this sequence version replaced gi:34876444.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.1"
     Protein         1..300
                     /product="geranylgeranyl diphosphate synthase 1"
                     /EC_number="2.5.1.1"
                     /EC_number="2.5.1.10"
                     /EC_number="2.5.1.29"
                     /calculated_mol_wt=34647
     CDS             1..300
                     /gene="Ggps1"
                     /gene_synonym="Crlf3"
                     /gene_synonym="rGGPS1a"
                     /gene_synonym="rGGPS1a1"
                     /gene_synonym="rGGPS1a2"
                     /gene_synonym="rGGPS1a3"
                     /coded_by="NM_001007626.2:249..1151"
                     /db_xref="GeneID:291211"
                     /db_xref="RGD:1359680"
ORIGIN      
        1 mektkekaer illepykyll qlpgkqvrtk lsqafnhwlk vpedklqiii evtemlhnas
       61 lliddiedss klrrgfpvah siygvpsvin sanyvyflgl ekvltldhpd avklftrqll
      121 elhqgqgldi ywrdtytcpt eeeykamvlq ktgglfglav glmqlfsdyk edlkplldtl
      181 glffqirddy anlhskeyse nksfcedlte gkfsfptiha iwsrpestqv qnilrqrten
      241 idikkycvqy ledvgsfeyt rytlreleak aykqieacgg npslvalvkh lskmfteene
//