LOCUS       NP_001005866            1303 aa            linear   ROD 24-OCT-2008
DEFINITION  F-box and leucine-rich repeat protein 10 isoform 3 [Mus musculus].
ACCESSION   NP_001005866
VERSION     NP_001005866.1  GI:54607024
DBSOURCE    REFSEQ: accession NM_001005866.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE   1  (residues 1 to 1303)
  AUTHORS   Allis,C.D., Berger,S.L., Cote,J., Dent,S., Jenuwien,T.,
            Kouzarides,T., Pillus,L., Reinberg,D., Shi,Y., Shiekhattar,R.,
            Shilatifard,A., Workman,J. and Zhang,Y.
  TITLE     New nomenclature for chromatin-modifying enzymes
  JOURNAL   Cell 131 (4), 633-636 (2007)
   PUBMED   18022353
REFERENCE   2  (residues 1 to 1303)
  AUTHORS   Sanchez,C., Sanchez,I., Demmers,J.A., Rodriguez,P., Strouboulis,J.
            and Vidal,M.
  TITLE     Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel
            complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6
            interacting corepressor
  JOURNAL   Mol. Cell Proteomics 6 (5), 820-834 (2007)
   PUBMED   17296600
  REMARK    GeneRIF: Study using a high throughput proteomics approach
            identified interactors with Rnf2 including Fbxl10/Jhdm1B, casein
            kinase subunits, and the BcoR corepressor
REFERENCE   3  (residues 1 to 1303)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev. 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   4  (residues 1 to 1303)
  AUTHORS   Winston,J.T., Koepp,D.M., Zhu,C., Elledge,S.J. and Harper,J.W.
  TITLE     A family of mammalian F-box proteins
  JOURNAL   Curr. Biol. 9 (20), 1180-1182 (1999)
   PUBMED   10531037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY011726.1 and BC065090.1.
            
            Transcript Variant: This variant (3) contains an alternate segment
            in the 5' UTR and 5' coding region, compared to variant 1. The
            resulting isoform (3) has a shorter and distinct N-terminus when
            compared to isoform 1.
FEATURES             Location/Qualifiers
     source          1..1303
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
     Protein         1..1303
                     /product="F-box and leucine-rich repeat protein 10 isoform
                     3"
                     /EC_number="1.14.11.27"
                     /note="F-box protein containing leucine repeats 10"
                     /calculated_mol_wt=148971
     CDS             1..1303
                     /gene="Fbxl10"
                     /gene_synonym="Cxxc2"
                     /gene_synonym="Fbl10"
                     /gene_synonym="KDM2B"
                     /gene_synonym="PCCX2"
                     /gene_synonym="Jhdm1b"
                     /gene_synonym="KIAA3014"
                     /gene_synonym="mKIAA3014"
                     /gene_synonym="E430001G17"
                     /coded_by="NM_001005866.1:53..3964"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS39260.1"
                     /db_xref="GeneID:30841"
                     /db_xref="MGI:1354737"
ORIGIN      
        1 mrqllraidr qrydenedls dveeivsvrg fsleeklrsq lyqgdfvham egkdfnyeyv
       61 qrealrvplv frdkdglgik mpdpdftvrd vkllvgsrrl vdvmdvntqk gtemsmsqfv
      121 ryyetpeaqr dklynvisle fshtklehlv krptvvdlvd wvdnmwpqhl kekqteatna
      181 laemkypkvk kyclmsvkgc ftdfhidfgg tsvwyhvfrg gkifwlippt lhnlalyeew
      241 vlsgkqsdif lgdrvercqr ielkqgytff ipsgwihavy tpvdslvfgg nilhsfnvpm
      301 qlriyeiedr trvqpkfryp fyyemcwyvl eryvycvtqr syltqeyqre lmlidaprkt
      361 svdgfssdsw ldmeeesceq qpqeeeeeee dkeeegdgad ktpkpptddp tsptstpped
      421 qdstgkkpka pairflkrtl sneseesvks tsmptddpkt ptgspatevs tkwthltefe
      481 lkglkalvek leslpenkkc vpegiedpqa llegvknvlk ehvdddptla itgvpvvswp
      541 kktaknrvvg rpkgklgpas avklaanrtt agarrrrtrc rkceaclrte cgechfckdm
      601 kkfggpgrmk qscimrqcia pvlphtavcl vcgeagkedt veeeegkfnl mlmecsicne
      661 iihpgclkik esegvvndel pncwecpkcn hagktgkqkr gpgfkyasnl pgsllkeqkm
      721 nrdnkegqep akrrseceea prrrsdehpk kvpadgilrr ksddvhlrrk rkyekpqels
      781 grkrasslqt spgssshlsp rpplgsslsp wwrssltyfq qqlkpgkedk lfrkkrrswk
      841 naedrlslan kplrrfkqep eddlpeappk tresdqsrss sptagpsteg aegpeekkkv
      901 kmrrkrrlvn kelskelske lnheiqktes tlahesqqpi ksepesende pkrplshcer
      961 phrfskglng tprelrhslg pglrspprvm srpppsaspp kciqmerhvi rpppispppd
     1021 slplddgaah vmhrevwmav fsylshrdlc vcmrvcrtwn rwccdkrlwt ridlnrcksi
     1081 tplmlsgiir rqpvsldlsw tniskkqlsw linrlpglrd lvlsgcswia vsalcssscp
     1141 llrtldvqwv eglkdaqmrd llspptdnrp gqmdnrsklr nivelrlagl ditdvslrli
     1201 irhmpllskl qlsycnhind qsinlltavg tttrdsltev nlsdcnkvtd lclsffkrcg
     1261 nichidlryc kqvtkegceq fiaemsvsvq fgqveekllq kls
//