LOCUS NP_001004343 147 aa linear PRI 05-NOV-2008
DEFINITION microtubule-associated protein 1 light chain 3 gamma [Homo
sapiens].
ACCESSION NP_001004343 XP_496447
VERSION NP_001004343.1 GI:51972260
DBSOURCE REFSEQ: accession NM_001004343.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (residues 1 to 147)
AUTHORS Gregory,S.G., Barlow,K.F., McLay,K.E., Kaul,R., Swarbreck,D.,
Dunham,A., Scott,C.E., Howe,K.L., Woodfine,K., Spencer,C.C.,
Jones,M.C., Gillson,C., Searle,S., Zhou,Y., Kokocinski,F.,
McDonald,L., Evans,R., Phillips,K., Atkinson,A., Cooper,R.,
Jones,C., Hall,R.E., Andrews,T.D., Lloyd,C., Ainscough,R.,
Almeida,J.P., Ambrose,K.D., Anderson,F., Andrew,R.W., Ashwell,R.I.,
Aubin,K., Babbage,A.K., Bagguley,C.L., Bailey,J., Beasley,H.,
Bethel,G., Bird,C.P., Bray-Allen,S., Brown,J.Y., Brown,A.J.,
Buckley,D., Burton,J., Bye,J., Carder,C., Chapman,J.C., Clark,S.Y.,
Clarke,G., Clee,C., Cobley,V., Collier,R.E., Corby,N.,
Coville,G.J., Davies,J., Deadman,R., Dunn,M., Earthrowl,M.,
Ellington,A.G., Errington,H., Frankish,A., Frankland,J., French,L.,
Garner,P., Garnett,J., Gay,L., Ghori,M.R., Gibson,R., Gilby,L.M.,
Gillett,W., Glithero,R.J., Grafham,D.V., Griffiths,C.,
Griffiths-Jones,S., Grocock,R., Hammond,S., Harrison,E.S., Hart,E.,
Haugen,E., Heath,P.D., Holmes,S., Holt,K., Howden,P.J., Hunt,A.R.,
Hunt,S.E., Hunter,G., Isherwood,J., James,R., Johnson,C.,
Johnson,D., Joy,A., Kay,M., Kershaw,J.K., Kibukawa,M.,
Kimberley,A.M., King,A., Knights,A.J., Lad,H., Laird,G., Lawlor,S.,
Leongamornlert,D.A., Lloyd,D.M., Loveland,J., Lovell,J., Lush,M.J.,
Lyne,R., Martin,S., Mashreghi-Mohammadi,M., Matthews,L.,
Matthews,N.S., McLaren,S., Milne,S., Mistry,S., Moore,M.J.,
Nickerson,T., O'Dell,C.N., Oliver,K., Palmeiri,A., Palmer,S.A.,
Parker,A., Patel,D., Pearce,A.V., Peck,A.I., Pelan,S., Phelps,K.,
Phillimore,B.J., Plumb,R., Rajan,J., Raymond,C., Rouse,G.,
Saenphimmachak,C., Sehra,H.K., Sheridan,E., Shownkeen,R., Sims,S.,
Skuce,C.D., Smith,M., Steward,C., Subramanian,S., Sycamore,N.,
Tracey,A., Tromans,A., Van Helmond,Z., Wall,M., Wallis,J.M.,
White,S., Whitehead,S.L., Wilkinson,J.E., Willey,D.L., Williams,H.,
Wilming,L., Wray,P.W., Wu,Z., Coulson,A., Vaudin,M., Sulston,J.E.,
Durbin,R., Hubbard,T., Wooster,R., Dunham,I., Carter,N.P.,
McVean,G., Ross,M.T., Harrow,J., Olson,M.V., Beck,S., Rogers,J.,
Bentley,D.R., Banerjee,R., Bryant,S.P., Burford,D.C., Burrill,W.D.,
Clegg,S.M., Dhami,P., Dovey,O., Faulkner,L.M., Gribble,S.M.,
Langford,C.F., Pandian,R.D., Porter,K.M. and Prigmore,E.
TITLE The DNA sequence and biological annotation of human chromosome 1
JOURNAL Nature 441 (7091), 315-321 (2006)
PUBMED 16710414
REMARK Erratum:[Nature. 2006 Oct 26;443(7114):1013. Banerjee, R [added];
Bryant, SP [added]; Burford, DC [added]; Burrill, WDH [added];
Clegg, SM [added]; Dhami, P [added]; Dovey, O [added]; Faulkner, LM
[added]; Gribble, SM [added]; Langford, CF [added]; Pandian, RD
[added]; Porter, KM [added]; Prigmore, E [added]]
REFERENCE 2 (residues 1 to 147)
AUTHORS Tanida,I., Sou,Y.S., Ezaki,J., Minematsu-Ikeguchi,N., Ueno,T. and
Kominami,E.
TITLE HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three
human Atg8 homologues and delipidates microtubule-associated
protein light chain 3- and GABAA receptor-associated
protein-phospholipid conjugates
JOURNAL J. Biol. Chem. 279 (35), 36268-36276 (2004)
PUBMED 15187094
REFERENCE 3 (residues 1 to 147)
AUTHORS He,H., Dang,Y., Dai,F., Guo,Z., Wu,J., She,X., Pei,Y., Chen,Y.,
Ling,W., Wu,C., Zhao,S., Liu,J.O. and Yu,L.
TITLE Post-translational modifications of three members of the human
MAP1LC3 family and detection of a novel type of modification for
MAP1LC3B
JOURNAL J. Biol. Chem. 278 (31), 29278-29287 (2003)
PUBMED 12740394
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CN260933.1, BC127722.1 and AF276659.1.
On Sep 16, 2004 this sequence version replaced gi:51459138.
Summary: Autophagy is a highly regulated bulk degradation process
that plays an important role in cellular maintenance and
development. MAP1LC3C is 1 of 3 orthologs of the yeast
autophagosome protein Atg8 (He et al., 2003 [PubMed
12740394]).[supplied by OMIM].
FEATURES Location/Qualifiers
source 1..147
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q43"
Protein 1..147
/product="microtubule-associated protein 1 light chain 3
gamma"
/note="MAP1 light chain 3-like protein 2; LC3-like protein
2"
/calculated_mol_wt=16720
CDS 1..147
/gene="MAP1LC3C"
/gene_synonym="LC3C"
/coded_by="NM_001004343.2:76..519"
/db_xref="CCDS:CCDS31074.1"
/db_xref="GeneID:440738"
/db_xref="HGNC:13353"
/db_xref="HPRD:14226"
/db_xref="MIM:609605"
ORIGIN
1 mpppqkipsv rpfkqrksla irqeevagir akfpnkipvv verypretfl ppldktkflv
61 pqeltmtqfl siirsrmvlr ateafyllvn nkslvsmsat maeiyrdykd edgfvymtya
121 sqetfgcles aaprdgssle drpcnpl
//