LOCUS       NP_001004214             231 aa            linear   ROD 24-OCT-2008
DEFINITION  NAD(P)H dehydrogenase, quinone 2 [Rattus norvegicus].
ACCESSION   NP_001004214 XP_214470
VERSION     NP_001004214.1  GI:51948400
DBSOURCE    REFSEQ: accession NM_001004214.1
KEYWORDS    .
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 231)
  AUTHORS   Brouillette,J. and Quirion,R.
  TITLE     Transthyretin: a key gene involved in the maintenance of memory
            capacities during aging
  JOURNAL   Neurobiol. Aging 29 (11), 1721-1732 (2008)
   PUBMED   17512093
REFERENCE   2  (residues 1 to 231)
  AUTHORS   Long,D.J. II, Iskander,K., Gaikwad,A., Arin,M., Roop,D.R., Knox,R.,
            Barrios,R. and Jaiswal,A.K.
  TITLE     Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2
            (NQO2) leads to myeloid hyperplasia of bone marrow and decreased
            sensitivity to menadione toxicity
  JOURNAL   J. Biol. Chem. 277 (48), 46131-46139 (2002)
   PUBMED   12351651
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079157.1.
            On Sep 10, 2004 this sequence version replaced gi:27685091.
            
            Summary: mouse homolog catalyzes the reduction of quinones and
            quinone derivatives; may protect against development of myelogenous
            hyperplasia , may contribute to menadione mediated hepatic toxicity
            [RGD].
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     Protein         1..231
                     /product="NAD(P)H dehydrogenase, quinone 2"
                     /EC_number="1.10.99.2"
                     /calculated_mol_wt=26144
     CDS             1..231
                     /gene="Nqo2"
                     /gene_synonym="MGC94180"
                     /coded_by="NM_001004214.1:104..799"
                     /db_xref="GeneID:291084"
                     /db_xref="RGD:1303320"
ORIGIN      
        1 magkkvllvy ahqepksfng smkqvaveel skqgctvtvs dlytmnfepr atrndvtgal
       61 snpevfkygi eayeaykkka ltsdileeqr kvqeadlvif qfplywfsvp ailkgwmdrv
      121 lcqgfafdvp gfydsgflkd klallsfttg gtaemytkag vngdfryflw plqhgtlhfc
      181 gfkvlapqis fgpevsseeq rkvmlaswvq rlksiwkeep ihctpswyfq g
//