LOCUS       NP_001003953            1309 aa            linear   ROD 24-OCT-2008
DEFINITION  F-box and leucine-rich repeat protein 10 isoform 1 [Mus musculus].
ACCESSION   NP_001003953 XP_144523
VERSION     NP_001003953.1  GI:54607022
DBSOURCE    REFSEQ: accession NM_001003953.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
REFERENCE   1  (residues 1 to 1309)
  AUTHORS   Allis,C.D., Berger,S.L., Cote,J., Dent,S., Jenuwien,T.,
            Kouzarides,T., Pillus,L., Reinberg,D., Shi,Y., Shiekhattar,R.,
            Shilatifard,A., Workman,J. and Zhang,Y.
  TITLE     New nomenclature for chromatin-modifying enzymes
  JOURNAL   Cell 131 (4), 633-636 (2007)
   PUBMED   18022353
REFERENCE   2  (residues 1 to 1309)
  AUTHORS   Sanchez,C., Sanchez,I., Demmers,J.A., Rodriguez,P., Strouboulis,J.
            and Vidal,M.
  TITLE     Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel
            complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6
            interacting corepressor
  JOURNAL   Mol. Cell Proteomics 6 (5), 820-834 (2007)
   PUBMED   17296600
  REMARK    GeneRIF: Study using a high throughput proteomics approach
            identified interactors with Rnf2 including Fbxl10/Jhdm1B, casein
            kinase subunits, and the BcoR corepressor
REFERENCE   3  (residues 1 to 1309)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev. 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   4  (residues 1 to 1309)
  AUTHORS   Winston,J.T., Koepp,D.M., Zhu,C., Elledge,S.J. and Harper,J.W.
  TITLE     A family of mammalian F-box proteins
  JOURNAL   Curr. Biol. 9 (20), 1180-1182 (1999)
   PUBMED   10531037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB640824.1 and BC065090.1.
            On Oct 25, 2004 this sequence version replaced gi:51827516.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
     Protein         1..1309
                     /product="F-box and leucine-rich repeat protein 10 isoform
                     1"
                     /EC_number="1.14.11.27"
                     /note="F-box protein containing leucine repeats 10"
                     /calculated_mol_wt=149603
     CDS             1..1309
                     /gene="Fbxl10"
                     /gene_synonym="Cxxc2"
                     /gene_synonym="Fbl10"
                     /gene_synonym="KDM2B"
                     /gene_synonym="PCCX2"
                     /gene_synonym="Jhdm1b"
                     /gene_synonym="KIAA3014"
                     /gene_synonym="mKIAA3014"
                     /gene_synonym="E430001G17"
                     /coded_by="NM_001003953.1:193..4122"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS39259.1"
                     /db_xref="GeneID:30841"
                     /db_xref="MGI:1354737"
ORIGIN      
        1 meaekdsgrr lraidrqryd enedlsdvee ivsvrgfsle eklrsqlyqg dfvhamegkd
       61 fnyeyvqrea lrvplvfrdk dglgikmpdp dftvrdvkll vgsrrlvdvm dvntqkgtem
      121 smsqfvryye tpeaqrdkly nvislefsht klehlvkrpt vvdlvdwvdn mwpqhlkekq
      181 teatnalaem kypkvkkycl msvkgcftdf hidfggtsvw yhvfrggkif wlipptlhnl
      241 alyeewvlsg kqsdiflgdr vercqrielk qgytffipsg wihavytpvd slvfggnilh
      301 sfnvpmqlri yeiedrtrvq pkfrypfyye mcwyvleryv ycvtqrsylt qeyqrelmli
      361 daprktsvdg fssdswldme eesceqqpqe eeeeeedkee egdgadktpk pptddptspt
      421 stppedqdst gkkpkapair flkrtlsnes eesvkstsmp tddpktptgs patevstkwt
      481 hltefelkgl kalveklesl penkkcvpeg iedpqalleg vknvlkehvd ddptlaitgv
      541 pvvswpkkta knrvvgrpkg klgpasavkl aanrttagar rrrtrcrkce aclrtecgec
      601 hfckdmkkfg gpgrmkqsci mrqciapvlp htavclvcge agkedtveee egkfnlmlme
      661 csicneiihp gclkikeseg vvndelpncw ecpkcnhagk tgkqkrgpgf kyasnlpgsl
      721 lkeqkmnrdn kegqepakrr seceeaprrr sdehpkkvpa dgilrrksdd vhlrrkrkye
      781 kpqelsgrkr asslqtspgs sshlsprppl gsslspwwrs sltyfqqqlk pgkedklfrk
      841 krrswknaed rlslankplr rfkqepeddl peappktres dqsrssspta gpstegaegp
      901 eekkkvkmrr krrlvnkels kelskelnhe iqktestlah esqqpiksep esendepkrp
      961 lshcerphrf skglngtpre lrhslgpglr spprvmsrpp psasppkciq merhvirppp
     1021 ispppdslpl ddgaahvmhr evwmavfsyl shrdlcvcmr vcrtwnrwcc dkrlwtridl
     1081 nrcksitplm lsgiirrqpv sldlswtnis kkqlswlinr lpglrdlvls gcswiavsal
     1141 cssscpllrt ldvqwveglk daqmrdllsp ptdnrpgqmd nrsklrnive lrlaglditd
     1201 vslrliirhm pllsklqlsy cnhindqsin lltavgtttr dsltevnlsd cnkvtdlcls
     1261 ffkrcgnich idlryckqvt kegceqfiae msvsvqfgqv eekllqkls
//