LOCUS       NP_001003194             403 aa            linear   MAM 22-OCT-2008
DEFINITION  renin [Canis lupus familiaris].
ACCESSION   NP_001003194
VERSION     NP_001003194.1  GI:50978946
DBSOURCE    REFSEQ: accession NM_001003194.1
KEYWORDS    .
SOURCE      Canis lupus familiaris (dog)
  ORGANISM  Canis lupus familiaris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Bukhtiyarov,Y., Zecher,M., Panemangalore,R., Wu,Z., Bruno,J.G.,
            Yuan,J., Xu,Z., Dillard,L.W., McGeehan,G.M., Harrison,R.K. and
            Scott,B.B.
  TITLE     Cloning, characterization and site-directed mutagenesis of canine
            renin
  JOURNAL   J. Biochem. 142 (6), 671-680 (2007)
   PUBMED   17942478
  REMARK    GeneRIF: Characterization of canine renin with mutations in the
            substrate binding site.
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Lee,Y.A., Liang,C.S., Lee,M.A. and Lindpaintner,K.
  TITLE     Local stress, not systemic factors, regulate gene expression of the
            cardiac renin-angiotensin system in vivo: a comprehensive study of
            all its components in the dog
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 93 (20), 11035-11040 (1996)
   PUBMED   8855304
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY630442.1.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Canis lupus familiaris"
                     /sub_species="familiaris"
                     /db_xref="taxon:9615"
                     /chromosome="38"
                     /map="38"
     Protein         1..403
                     /product="renin"
                     /EC_number="3.4.23.15"
                     /calculated_mol_wt=43968
     CDS             1..403
                     /gene="REN"
                     /coded_by="NM_001003194.1:1..1212"
                     /db_xref="GeneID:403838"
ORIGIN      
        1 marcrmprwg lllvlwgsct fglpadtgaf rriflkkmps ireslkergv dvaglgaewn
       61 qftkrlssgn stspvvltny ldtqyygeig igtppqtfkv vfdtgsanlw vpstrcsply
      121 taceihclyd ssesssymen gttftirygs gkvkgflsqd mvtvggitvt qtfgevtelp
      181 lipfmlakfd gvlgmgfpaq avggvtpvfd hilsqgvlke evfsvyysrn shllggevvl
      241 ggsdpqyyqg nfhyvsiskt gswqikmkgv svrsatlvce egcmvvvdtg asyisgptss
      301 lrllmdtlga qelstneyvv ncnqvptlpd isfhlggray tltskdyvlq dpygnedlct
      361 lalhgldvpp ptgpvwvlga sfirkfytef drhnnrigfa lar
//