RecName: Full=Lymphocyte activation gene 3 protein; Short=LAG-3; AltNa - Protein

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Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function. [Proc Natl Acad Sci U S A. 2024]
Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function.
Silberstein JL, Du J, Chan KW, Frank JA, Mathews II, Kim YB, You J, Lu Q, Liu J, Philips EA, et al. Proc Natl Acad Sci U S A. 2024 Mar 19; 121(12):e2310866121. Epub 2024 Mar 14.
Signatures of glial activity can be detected in the CSF proteome. [Proc Natl Acad Sci U S A. 2022]
Signatures of glial activity can be detected in the CSF proteome.
Eninger T, Müller SA, Bacioglu M, Schweighauser M, Lambert M, Maia LF, Neher JJ, Hornfeck SM, Obermüller U, Kleinberger G, et al. Proc Natl Acad Sci U S A. 2022 Jun 14; 119(24):e2119804119. Epub 2022 Jun 6.
Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity. [Immunity. 2022]
Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity.
Maruhashi T, Sugiura D, Okazaki IM, Shimizu K, Maeda TK, Ikubo J, Yoshikawa H, Maenaka K, Ishimaru N, Kosako H, et al. Immunity. 2022 May 10; 55(5):912-924.e8. Epub 2022 Apr 11.

RefSeq protein
See the reference protein sequence for lymphocyte activation gene 3 protein precursor (NP_032505.1).

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Lymphocyte activation gene 3 protein; Short=LAG-3; AltName: Full=A...
RecName: Full=Lymphocyte activation gene 3 protein; Short=LAG-3; AltName: Full=Activation-induced cytidine deaminase-linked autoimmunity protein; Short=Aida; AltName: CD_antigen=CD223; Contains: RecName: Full=Secreted lymphocyte activation gene 3 protein; Short=sLAG-3; Flags: Precursor
gi|2497295|sp|Q61790.1|LAG3_MOUSE

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