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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108944722.

Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis

Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu, Zhenshun Cheng

Respir Res. 2024; 25: 100. Published online 2024 Feb 24. doi: 10.1186/s12931-024-02740-2

PMCID:: PMC10894472

Abstract Article PDF–7.5M

Select item 108467033.

BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia

Miguel A. B. Mercado, Qiang Li, Charles M. Quick, Yejin Kim, Rachel Palmer, Lu Huang, Lin-Xi Li

PLoS Pathog. 2024 Jan; 20(1): e1011983. Published online 2024 Jan 25. doi: 10.1371/journal.ppat.1011983

PMCID:: PMC10846703

Abstract Article PDF–2.9M

Select item 107630664.

Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder

Fuyuki Sato, Ujjal K. Bhawal, Kosuke Oikawa, Yasuteru Muragaki

BMC Mol Cell Biol. 2024; 25: 1. Published online 2024 Jan 2. doi: 10.1186/s12860-023-00497-y

PMCID:: PMC10763066

Abstract Article PDF–3.8M

Select item 106954125.

BHLHE40 Mediates Cross-Talk between Pathogenic T_H17 Cells and Myeloid Cells during Experimental Autoimmune Encephalomyelitis

Melissa E. Cook, Irina Shchukina, Chih-Chung Lin, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Nicholas N. Jarjour, Ashlee M. Webber, Konstantin Zaitsev, Maxim N. Artyomov, Brian T. Edelson

Immunohorizons. 2023 Nov; 7(11): 737–746. Published online 2023 Nov 7. doi: 10.4049/immunohorizons.2300042

PMCID:: PMC10695412

Abstract Article PDF–4.3M

Select item 106875326.

Cisplatin increases carboxylesterases through increasing PXR mediated by the decrease of DEC1

Minqin Xu, Lihua Zhang, Lan Lin, Zhiyi Qiang, Wei Liu, Jian Yang

J Biomed Res. 2023 Nov; 37(6): 431–447. Published online 2023 Nov 15. doi: 10.7555/JBR.37.20230047

PMCID:: PMC10687532

Abstract Article PDF–13M

Select item 106529037.

Bhlhe40 limits early IL-10 production from CD4⁺ T cells during Plasmodium yoelii 17X infection

Kara A. O'Neal, Sheldon L. Zeltner, Camille L. Foscue, Jason S. Stumhofer

Infect Immun. 2023 Nov; 91(11): e00367-23. Published online 2023 Oct 16. doi: 10.1128/iai.00367-23

PMCID:: PMC10652903

Abstract Article PDF–5.4M

Select item 103904928.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 100118309.

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis

Yichen Wu, Haobin Wang, Ying Huo, Bingfang Yan, Hiroaki Honda, Wei Liu, Jian Yang

J Biol Chem. 2023 Mar; 299(3): 102982. Published online 2023 Feb 3. doi: 10.1016/j.jbc.2023.102982

PMCID:: PMC10011830

Abstract Article PDF–5.6M

Select item 995046510.

Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis

Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S. Duncan, Chunxing Zheng, Christoph Göbl, Kyle T. Gill, Jillian Haight, Andrew C. Wakeham, Bryan E. Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E. Saunders, Richard A. Flavell, Tak W. Mak

Cell Death Differ. 2023 Feb; 30(2): 407–416. Published online 2022 Dec 17. doi: 10.1038/s41418-022-01092-y

PMCID:: PMC9950465

Abstract Article PDF–2.8M

Select item 982032211.

Ribosomal Stress Couples with the Hypoxia Response in Dec1-Dependent Orthodontic Tooth Movement

Shigeru Nakamura, Keiji Tanimoto, Ujjal K. Bhawal

Int J Mol Sci. 2023 Jan; 24(1): 618. Published online 2022 Dec 29. doi: 10.3390/ijms24010618

PMCID:: PMC9820322

Abstract Article PDF–16M

Select item 938646412.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 898091213.

DEC1 promotes progression of Helicobacter pylori‐positive gastric cancer by regulating Akt/NF‐κB pathway

Yanfei Jia, Yanyan Liu, Jingyu Zhu, Liang Liu, Xiaoli Ma, Duanrui Liu, Shuyi Han, Lulu Zhang, Zhi‐Qiang Ling, Yunshan Wang

J Cell Mol Med. 2022 Apr; 26(7): 1943–1954. Published online 2022 Feb 4. doi: 10.1111/jcmm.17219

PMCID:: PMC8980912

Abstract Article PDF–2.2M

Select item 895985414.

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway

Xingxing Hu, Menglin Zou, Lan Ni, Mingyang Zhang, Weishuai Zheng, Bing Liu, Zhenshun Cheng

Front Pharmacol. 2022; 13: 829673. Published online 2022 Mar 9. doi: 10.3389/fphar.2022.829673

PMCID:: PMC8959854

Abstract Article PDF–9.6M

Select item 868966515.

Bhlhe40 function in activated B and T_FH cells restrains the GC reaction and prevents lymphomagenesis

René Rauschmeier, Annika Reinhardt, Charlotte Gustafsson, Vassilis Glaros, Artem V. Artemov, Josefine Dunst, Reshma Taneja, Igor Adameyko, Robert Månsson, Meinrad Busslinger, Taras Kreslavsky

J Exp Med. 2022 Feb 7; 219(2): e20211406. Published online 2021 Dec 17. doi: 10.1084/jem.20211406

PMCID:: PMC8689665

Abstract Article PDF–8.0M

Select item 860735516.

BHLHE40 promotes macrophage pro-inflammatory gene expression and functions

Atif Zafar, Hang Pong Ng, Gun-Dong Kim, E. Ricky Chan, Ganapati H. Mahabeleshwar

FASEB J. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: FASEB J. 2021 Oct; 35(10): e21940. doi: 10.1096/fj.202100944R

PMCID:: PMC8607355

Abstract Article PDF–3.0M

Select item 847913517.

CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN

Daisuke Ono, Ken-ichi Honma, Christoph Schmal, Toru Takumi, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato, Sato Honma

Sci Rep. 2021; 11: 19240. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98532-5

PMCID:: PMC8479135

Abstract Article PDF–2.2M

Select item 831672818.

Icariin protects against glucocorticoid induced osteoporosis, increases the expression of the bone enhancer DEC1 and modulates the PI3K/Akt/GSK3β/β-catenin integrated signaling pathway

Hu Jinhua, Mao Zhao, He Shuangcheng, Zhan Yuanran, Ning Rui, Liu Wei, Yan Bingfang, Yang Jian

Biochem Pharmacol. Author manuscript; available in PMC 2021 Jul 28.

Published in final edited form as: Biochem Pharmacol. 2017 Jul 15; 136: 109–121. Published online 2017 Apr 11. doi: 10.1016/j.bcp.2017.04.010

PMCID:: PMC8316728

Abstract Article PDF–1.1M

Select item 831323919.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 831138320.

DEC1 deficiency results in accelerated osteopenia through enhanced DKK1 activity and attenuated PI3KCA/Akt/GSK3β signaling

Shuangcheng He, Yu Guan, Yichen Wu, Ling Zhu, Bingfang Yan, Hiroaki Honda, Jian Yang, Wei Liu

Metabolism. Author manuscript; available in PMC 2021 Jul 26.

Published in final edited form as: Metabolism. 2021 May; 118: 154730. Published online 2021 Feb 17. doi: 10.1016/j.metabol.2021.154730

PMCID:: PMC8311383

Abstract Article PDF–3.6M

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