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Select item 92871231.

Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study

Dongjing Liu, Benjamin E. Zusman, John R. Shaffer, Yunqi Li, Annie I. Arockiaraj, Shuwei Liu, Daniel E. Weeks, Shashvat M. Desai, Patrick M. Kochanek, Ava M. Puccio, David O. Okonkwo, Yvette P. Conley, Ruchira M. Jha

Neurocrit Care. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Neurocrit Care. 2022 Aug; 37(1): 26–37. Published online 2022 Jan 13. doi: 10.1007/s12028-021-01424-9

PMCID:: PMC9287123

Abstract Article PDF–1.2M

Select item 92626142.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92594963.

Whole-genome sequencing reveals host factors underlying critical COVID-19

Athanasios Kousathanas, Erola Pairo-Castineira, Konrad Rawlik, Alex Stuckey, Christopher A. Odhams, Susan Walker, Clark D. Russell, Tomas Malinauskas, Yang Wu, Jonathan Millar, Xia Shen, Katherine S. Elliott, Fiona Griffiths, Wilna Oosthuyzen, Kirstie Morrice, Sean Keating, Bo Wang, Daniel Rhodes, Lucija Klaric, Marie Zechner, Nick Parkinson, Afshan Siddiq, Peter Goddard, Sally Donovan, David Maslove, Alistair Nichol, Malcolm G. Semple, Tala Zainy, Fiona Maleady-Crowe, Linda Todd, Shahla Salehi, Julian Knight, Greg Elgar, Georgia Chan, Prabhu Arumugam, Christine Patch, Augusto Rendon, David Bentley, Clare Kingsley, Jack A. Kosmicki, Julie E. Horowitz, Aris Baras, Goncalo R. Abecasis, Manuel A. R. Ferreira, Anne Justice, Tooraj Mirshahi, Matthew Oetjens, Daniel J. Rader, Marylyn D. Ritchie, Anurag Verma, Tom A. Fowler, Manu Shankar-Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Danny McAuley, Hugh Montgomery, Peter J. M. Openshaw, Paul Elliott, Timothy Walsh, Albert Tenesa, GenOMICC investigators, 23andMe investigators, COVID-19 Human Genetics Initiative, Angie Fawkes, Lee Murphy, Kathy Rowan, Chris P. Ponting, Veronique Vitart, James F. Wilson, Jian Yang, Andrew D. Bretherick, Richard H. Scott, Sara Clohisey Hendry, Loukas Moutsianas, Andy Law, Mark J. Caulfield, J. Kenneth Baillie

Nature. 2022; 607(7917): 97–103. Published online 2022 Mar 7. doi: 10.1038/s41586-022-04576-6

PMCID:: PMC9259496

Abstract Article PDF–7.8M

Select item 81129124.

Repulsive Guidance Molecule-a and Central Nervous System Diseases

Jinhua Tang, Xiaopeng Zeng, Hang Li, Lu Ju, Jinzhou Feng, Jun Yang

Biomed Res Int. 2021; 2021: 5532116. Published online 2021 May 4. doi: 10.1155/2021/5532116

PMCID:: PMC8112912

Abstract Article PDF–733K

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67293536.

The Repulsive Guidance Molecule RGMa Is Involved in the Formation of Afferent Connections in the Dentate Gyrus

Henriette Brinks, Sabine Conrad, Johannes Vogt, Judit Oldekamp, Ana Sierra, Lutz Deitinghoff, Ingo Bechmann, Gonzalo Alvarez-Bolado, Bernd Heimrich, Philippe P. Monnier, Bernhard K. Mueller, Thomas Skutella

J Neurosci. 2004 Apr 14; 24(15): 3862–3869. doi: 10.1523/JNEUROSCI.5296-03.2004

PMCID:: PMC6729353

Abstract Article PDF–1.0M

Select item 66658957.

Inactivation of Ras by p120GAP via Focal Adhesion Kinase Dephosphorylation Mediates RGMa-Induced Growth Cone Collapse

Mitsuharu Endo, Toshihide Yamashita

J Neurosci. 2009 May 20; 29(20): 6649–6662. doi: 10.1523/JNEUROSCI.0927-09.2009

PMCID:: PMC6665895

Abstract Article PDF–1.7M

Select item 65967658.

Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease

Joanna A. Korecka, Elizabeth B. Moloney, Ruben Eggers, Barbara Hobo, Sanny Scheffer, Nienke Ras-Verloop, R. Jeroen Pasterkamp, Dick F. Swaab, August B. Smit, Ronald E. van Kesteren, Koen Bossers, Joost Verhaagen

J Neurosci. 2017 Sep 27; 37(39): 9361–9379. doi: 10.1523/JNEUROSCI.0084-17.2017

PMCID:: PMC6596765

Abstract Article PDF–7.6M

Select item 60411809.

Genome-wide association study identifies a regulatory variant of RGMA associated with opioid dependence in European Americans

Zhongshan Cheng, Hang Zhou, Richard Sherva, Lindsay Farrer, Henry R. Kranzler, Joel Gelernter

Biol Psychiatry. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Biol Psychiatry. 2018 Nov 15; 84(10): 762–770. Published online 2018 Jan 11. doi: 10.1016/j.biopsych.2017.12.016

PMCID:: PMC6041180

Abstract Article PDF–549K

Select item 448120510.

Bruno D. Fonseca, Chadi Zakaria, Jian-Jun Jia, Tyson E. Graber, Yuri Svitkin, Soroush Tahmasebi, Danielle Healy, Huy-Dung Hoang, Jacob M. Jensen, Ilo T. Diao, Alexandre Lussier, Christopher Dajadian, Niranjan Padmanabhan, Walter Wang, Edna Matta-Camacho, Jaclyn Hearnden, Ewan M. Smith, Yoshinori Tsukumo, Akiko Yanagiya, Masahiro Morita, Emmanuel Petroulakis, Jose L. González, Greco Hernández, Tommy Alain, Christian K. Damgaard

J Biol Chem. 2015 Jun 26; 290(26): 15996–16020. Published online 2015 May 4. doi: 10.1074/jbc.M114.621730

PMCID:: PMC4481205

Abstract Article PDF–5.8M

Select item 424279511.

Molecular biology, genetics and biochemistry of the repulsive guidance molecule family

Christopher J. Severyn, Ujwal Shinde, Peter Rotwein

Biochem J. Author manuscript; available in PMC 2014 Nov 24.

Published in final edited form as: Biochem J. 2009 Sep 15; 422(3): 393–403. Published online 2009 Aug 27. doi: 10.1042/BJ20090978

PMCID:: PMC4242795

Abstract Article PDF–2.0M

Select item 413679912.

Genome-Wide Association Studies and Heritability Estimates of Body Mass Index Related Phenotypes in Bangladeshi Adults

Molly Scannell Bryan, Maria Argos, Brandon Pierce, Lin Tong, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Mahfuzar Rahman, Tariqul Islam, Muhammad Yunus, Faruque Parvez, Shantanu Roy, Farzana Jasmine, John A. Baron, Muhammad G. Kibriya, Habibul Ahsan

PLoS One. 2014; 9(8): e105062. Published online 2014 Aug 18. doi: 10.1371/journal.pone.0105062

PMCID:: PMC4136799

Abstract Article PDF–692K

Select item 353039713.

GENOMIC ASSOCIATION ANALYSIS IDENTIFIES MULTIPLE LOCI INFLUENCING ANTIHYPERTENSIVE RESPONSE TO AN ANGIOTENSIN II RECEPTOR BLOCKER

Stephen T. Turner, Kent R. Bailey, Gary L. Schwartz, Arlene B. Chapman, High Seng Chai, Eric Boerwinkle

Hypertension. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Hypertension. 2012 Jun; 59(6): 1204–1211. Published online 2012 May 7. doi: 10.1161/HYP.0b013e31825b30f8

PMCID:: PMC3530397

Abstract Article PDF–1.3M

Select item 344793914.

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

Niina Sandholm, Rany M. Salem, Amy Jayne McKnight, Eoin P. Brennan, Carol Forsblom, Tamara Isakova, Gareth J. McKay, Winfred W. Williams, Denise M. Sadlier, Ville-Petteri Mäkinen, Elizabeth J. Swan, Cameron Palmer, Andrew P. Boright, Emma Ahlqvist, Harshal A. Deshmukh, Benjamin J. Keller, Huateng Huang, Aila J. Ahola, Emma Fagerholm, Daniel Gordin, Valma Harjutsalo, Bing He, Outi Heikkilä, Kustaa Hietala, Janne Kytö, Päivi Lahermo, Markku Lehto, Raija Lithovius, Anne-May Österholm, Maija Parkkonen, Janne Pitkäniemi, Milla Rosengård-Bärlund, Markku Saraheimo, Cinzia Sarti, Jenny Söderlund, Aino Soro-Paavonen, Anna Syreeni, Lena M. Thorn, Heikki Tikkanen, Nina Tolonen, Karl Tryggvason, Jaakko Tuomilehto, Johan Wadén, Geoffrey V. Gill, Sarah Prior, Candace Guiducci, Daniel B. Mirel, Andrew Taylor, S. Mohsen Hosseini, DCCT/EDIC Research Group, Hans-Henrik Parving, Peter Rossing, Lise Tarnow, Claes Ladenvall, François Alhenc-Gelas, Pierre Lefebvre, Vincent Rigalleau, Ronan Roussel, David-Alexandre Tregouet, Anna Maestroni, Silvia Maestroni, Henrik Falhammar, Tianwei Gu, Anna Möllsten, Danut Cimponeriu, Mihai Ioana, Maria Mota, Eugen Mota, Cristian Serafinceanu, Monica Stavarachi, Robert L. Hanson, Robert G. Nelson, Matthias Kretzler, Helen M. Colhoun, Nicolae Mircea Panduru, Harvest F. Gu, Kerstin Brismar, Gianpaolo Zerbini, Samy Hadjadj, Michel Marre, Leif Groop, Maria Lajer, Shelley B. Bull, Daryl Waggott, Andrew D. Paterson, David A. Savage, Stephen C. Bain, Finian Martin, Joel N. Hirschhorn, Catherine Godson, Jose C. Florez, Per-Henrik Groop, Alexander P. Maxwell

PLoS Genet. 2012 Sep; 8(9): e1002921. Published online 2012 Sep 20. doi: 10.1371/journal.pgen.1002921

PMCID:: PMC3447939

Abstract Article PDF–571K

Select item 329161015.

Identification of the Neogenin-Binding Site on the Repulsive Guidance Molecule A

Takahide Itokazu, Yuki Fujita, Ryosuke Takahashi, Toshihide Yamashita

PLoS One. 2012; 7(3): e32791. Published online 2012 Mar 1. doi: 10.1371/journal.pone.0032791

PMCID:: PMC3291610

Abstract Article PDF–480K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 308099617.

Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation

Valbona Mirakaj, Sebastian Brown, Stefanie Laucher, Carolin Steinl, Gerd Klein, David Köhler, Thomas Skutella, Christian Meisel, Benedikt Brommer, Peter Rosenberger, Jan M. Schwab

Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16): 6555–6560. Published online 2011 Apr 5. doi: 10.1073/pnas.1015605108

PMCID:: PMC3080996

Abstract Article PDF–1.0M

Select item 303367218.

Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells

Ok-Hee Lee, Hyeung Kim, Quanyuan He, Hwa Jin Baek, Dong Yang, Liuh-Yow Chen, Jiancong Liang, Heekyung Kate Chae, Amin Safari, Dan Liu, Zhou Songyang

Mol Cell Proteomics. 2011 Feb; 10(2): M110.001628. Published online 2010 Nov 11. doi: 10.1074/mcp.M110.001628

PMCID:: PMC3033672

Abstract Article PDF–1.5M

Select item 268640919.

Unc5B associates with LARG to mediate the action of repulsive guidance molecule

Katsuhiko Hata, Kozo Kaibuchi, Shinobu Inagaki, Toshihide Yamashita

J Cell Biol. 2009 Mar 9; 184(5): 737–750. doi: 10.1083/jcb.200807029

PMCID:: PMC2686409

Abstract Article PDF–5.9M

Select item 243523020.

Linkage Disequilibrium Mapping of a Chromosome 15q25–26 Major Depression Linkage Region and Sequencing of NTRK3

Ranjana Verma, Peter Holmans, James A. Knowles, Deepak Grover, Oleg V. Evgrafov, Raymond R. Crowe, William A. Scheftner, Myrna M. Weissman, J. Raymond DePaulo, Jr, James B. Potash, Douglas F. Levinson

Biol Psychiatry. Author manuscript; available in PMC 2009 Jun 15.

Published in final edited form as: Biol Psychiatry. 2008 Jun 15; 63(12): 1185–1189. Published online 2008 Mar 25. doi: 10.1016/j.biopsych.2008.02.005