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Select item 106161051.

Microglia-mediated demyelination protects against CD8⁺ T cell-driven axon degeneration in mice carrying PLP defects

Janos Groh, Tassnim Abdelwahab, Yogita Kattimani, Michaela Hörner, Silke Loserth, Viktoria Gudi, Robert Adalbert, Fabian Imdahl, Antoine-Emmanuel Saliba, Michael Coleman, Martin Stangel, Mikael Simons, Rudolf Martini

Nat Commun. 2023; 14: 6911. Published online 2023 Oct 30. doi: 10.1038/s41467-023-42570-2

PMCID:: PMC10616105

Abstract Article PDF–11M

Select item 104859562.

Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon

Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw

Neural Dev. 2023; 18: 5. Published online 2023 Sep 8. doi: 10.1186/s13064-023-00173-z

PMCID:: PMC10485956

Abstract Article PDF–15M

Select item 103931933.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Abstract Article PDF–22M

Select item 102964034.

PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development

Vanessa Waldhauser, Tina Baroti, Franziska Fröb, Michael Wegner

Cells. 2023 Jun; 12(12): 1556. Published online 2023 Jun 6. doi: 10.3390/cells12121556

PMCID:: PMC10296403

Abstract Article PDF–20M

Select item 102473805.

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A. Berghoff, Taisiia Nazarenko, Katharina Overhoff, Agnes A. Steixner-Kumar, Swati Subramanian, Sahab Arinrad, Torben Ruhwedel, Wiebke Möbius, Sandra Göbbels, Gesine Saher, Hauke B. Werner, Alkmini Damkou, Silvia Zampar, Oliver Wirths, Maik Thalmann, Mikael Simons, Takashi Saito, Takaomi Saido, Dilja Krueger-Burg, Riki Kawaguchi, Michael Willem, Christian Haass, Daniel Geschwind, Hannelore Ehrenreich, Ruth Stassart, Klaus-Armin Nave

Nature. 2023; 618(7964): 349–357. Published online 2023 May 31. doi: 10.1038/s41586-023-06120-6

PMCID:: PMC10247380

Abstract Article PDF–19M

Select item 101727886.

Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice

Tassnim Abdelwahab, David Stadler, Konrad Knöpper, Panagiota Arampatzi, Antoine-Emmanuel Saliba, Wolfgang Kastenmüller, Rudolf Martini, Janos Groh

iScience. 2023 May 19; 26(5): 106698. Published online 2023 Apr 19. doi: 10.1016/j.isci.2023.106698

PMCID:: PMC10172788

Abstract Article PDF–8.0M

Select item 99228697.

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse

Carmen Cifuentes-Diaz, Giorgia Canali, Marta Garcia, Mélanie Druart, Taylor Manett, Mythili Savariradjane, Camille Guillaume, Corentin Le Magueresse, Laurence Goutebroze

Front Neurosci. 2023; 17: 1100121. Published online 2023 Jan 30. doi: 10.3389/fnins.2023.1100121

PMCID:: PMC9922869

Abstract Article PDF–6.4M

Select item 96758548.

Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome

Isabel Pijuan, Elisa Balducci, Cristina Soto-Sánchez, Eduardo Fernández, María José Barallobre, Maria L. Arbonés

Sci Rep. 2022; 12: 19912. Published online 2022 Nov 19. doi: 10.1038/s41598-022-24284-5

PMCID:: PMC9675854

Abstract Article PDF–4.8M

Select item 89990359.

TRPV2: A Key Player in Myelination Disorders of the Central Nervous System

Jennifer Enrich-Bengoa, Gemma Manich, Tony Valente, Paula Sanchez-Molina, Beatriz Almolda, Carme Solà, Josep Saura, Berta González, Bernardo Castellano, Alex Perálvarez-Marín

Int J Mol Sci. 2022 Apr; 23(7): 3617. Published online 2022 Mar 25. doi: 10.3390/ijms23073617

PMCID:: PMC8999035

Abstract Article PDF–4.0M

Select item 898804410.

Rnf220 is Implicated in the Dorsoventral Patterning of the Hindbrain Neural Tube in Mice

Yu-Bing Wang, Ning-Ning Song, Lei Zhang, Pengcheng Ma, Jia-Yin Chen, Ying Huang, Ling Hu, Bingyu Mao, Yu-Qiang Ding

Front Cell Dev Biol. 2022; 10: 831365. Published online 2022 Mar 24. doi: 10.3389/fcell.2022.831365

PMCID:: PMC8988044

Abstract Article PDF–3.2M

Select item 878413311.

GATOR2 complex–mediated amino acid signaling regulates brain myelination

Zongyan Yu, Zhiwen Yang, Guoru Ren, Yingjie Wang, Xiang Luo, Feiyan Zhu, Shouyang Yu, Lanlan Jia, Mina Chen, Paul F. Worley, Bo Xiao

Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2110917119. Published online 2022 Jan 12. doi: 10.1073/pnas.2110917119

PMCID:: PMC8784133

Abstract Article PDF–3.3M

Select item 875075612.

Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation

Meitar Grad, Ariel Nir, Gilad Levy, Sari Schokoroy Trangle, Guy Shapira, Noam Shomron, Yaniv Assaf, Boaz Barak

Cells. 2022 Jan; 11(1): 158. Published online 2022 Jan 4. doi: 10.3390/cells11010158

PMCID:: PMC8750756

Abstract Article PDF–24M

Select item 862480713.

The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system

Johanna Tüshaus, Stephan A. Müller, Joshua Shrouder, Martina Arends, Mikael Simons, Nikolaus Plesnila, Carl P. Blobel, Stefan F. Lichtenthaler

FASEB J. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: FASEB J. 2021 Nov; 35(11): e21962. doi: 10.1096/fj.202100936R

PMCID:: PMC8624807

Abstract Article PDF–1.3M

Select item 860003414.

Identifying oligodendrocyte enhancers governing Plp1 expression

Dongkyeong Kim, Hongjoo An, Chuandong Fan, Yungki Park

Hum Mol Genet. 2021 Dec 1; 30(23): 2225–2239. Published online 2021 Jul 6. doi: 10.1093/hmg/ddab184

PMCID:: PMC8600034

Abstract Article PDF–2.3M

Select item 849299615.

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers

Ruyi Mei, Linyu Huang, Mengyuan Wu, Chunxia Jiang, Aifen Yang, Huaping Tao, Kang Zheng, Junlin Yang, Wanhua Shen, Xianjun Chen, Xiaofeng Zhao, Mengsheng Qiu

Front Cell Neurosci. 2021; 15: 751439. Published online 2021 Sep 22. doi: 10.3389/fncel.2021.751439

PMCID:: PMC8492996

Abstract Article PDF–3.0M

Select item 841187716.

Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor–endothelial cell crosstalk

Isidora Paredes, José Ricardo Vieira, Bhavin Shah, Carla F. Ramunno, Julia Dyckow, Heike Adler, Melanie Richter, Geza Schermann, Evangelia Giannakouri, Lucas Schirmer, Hellmut G. Augustin, Carmen Ruiz de Almodóvar

Nat Neurosci. Author manuscript; available in PMC 2021 Sep 2.

Published in final edited form as: Nat Neurosci. 2021 Apr; 24(4): 478–488. Published online 2021 Jan 28. doi: 10.1038/s41593-020-00788-z

PMCID:: PMC8411877

Abstract Article PDF–5.3M

Select item 832000217.

Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain

Eman Abbas, Mohamed A. Hassan, Godwin Sokpor, Kamila Kiszka, Linh Pham, Cemil Kerimoglu, Andre Fischer, Huu Phuc Nguyen, Jochen F. Staiger, Tran Tuoc

Front Cell Dev Biol. 2021; 9: 619538. Published online 2021 Jul 15. doi: 10.3389/fcell.2021.619538

PMCID:: PMC8320002

Abstract Article PDF–18M

Select item 828212418.

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

Hiroko Nobuta, Nan Yang, Yi Han Ng, Samuele G. Marro, Khalida Sabeur, Manideep Chavali, John H. Stockley, David W. Killilea, Patrick B. Walter, Chao Zhao, Philip Huie, Jr., Steven A. Goldman, Arnold R. Kriegstein, Robin J.M. Franklin, David H. Rowitch, Marius Wernig

Cell Stem Cell. Author manuscript; available in PMC 2021 Jul 15.

Published in final edited form as: Cell Stem Cell. 2019 Oct 3; 25(4): 531–541.e6. doi: 10.1016/j.stem.2019.09.003

PMCID:: PMC8282124

Abstract Article PDF–2.8M

Select item 824219319.

Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon

Mary Jo Talley, Diana Nardini, Nisha Shabbir, Lisa A. Ehrman, Carlos E. Prada, Ronald R. Waclaw

Front Cell Dev Biol. 2021; 9: 673995. Published online 2021 Jun 16. doi: 10.3389/fcell.2021.673995

PMCID:: PMC8242193

Abstract Article PDF–7.6M

Select item 821155220.

GPR84 Is Essential for the Taste of Medium Chain Saturated Fatty Acids

Yan Liu, Han Xu, Naima Dahir, Ashley Calder, Fangjun Lin, Timothy A. Gilbertson

J Neurosci. 2021 Jun 16; 41(24): 5219–5228. doi: 10.1523/JNEUROSCI.2530-20.2021

PMCID:: PMC8211552

Abstract Article PDF–773K

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