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Select item 106520391.

The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation

Eugene E. Kim, Akshay Shekhar, Jayalakshmi Ramachandran, Alireza Khodadadi-Jamayran, Fang-Yu Liu, Jie Zhang, Glenn I. Fishman

Development. 2023 Nov 1; 150(21): dev202054. Published online 2023 Oct 24. doi: 10.1242/dev.202054

PMCID:: PMC10652039

Abstract Article

Select item 104787532.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 104042863.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 102808534.

Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer

Caiqin Wang, Bo Xie, Shi Yin, Jianghua Cao, Junhao Huang, Longyang Jin, Ge Du, Xiaohui Zhai, Rongqin Zhang, Shanshan Li, Taiyuan Cao, Hongen Yu, Xinjuan Fan, Zuli Yang, Junsheng Peng, Jian Xiao, Lei Lian

J Transl Med. 2023; 21: 399. Published online 2023 Jun 19. doi: 10.1186/s12967-023-04156-w

PMCID:: PMC10280853

Abstract Article PDF–3.3M

Select item 101487275.

ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest

Lizhu Lin, Antonella Pinto, Lu Wang, Kazumi Fukatsu, Yan Yin, Simon D Bamforth, Marianne E Bronner, Sylvia M Evans, Shuyi Nie, Robert H Anderson, Alexey V Terskikh, Paul D Grossfeld

Hum Mol Genet. 2022 Dec 15; 31(24): 4217–4227. Published online 2022 Jul 28. doi: 10.1093/hmg/ddac174

PMCID:: PMC10148727

Abstract Article PDF–2.2M

Select item 100013726.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich

Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721

PMCID:: PMC10001372

Abstract Article PDF–2.7M

Select item 99078277.

Filamin C is Essential for mammalian myocardial integrity

Tongbin Wu, Yujun Xu, Lunfeng Zhang, Zhengyu Liang, Xiaohai Zhou, Sylvia M. Evans, Ju Chen

PLoS Genet. 2023 Jan; 19(1): e1010630. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010630

PMCID:: PMC9907827

Abstract Article PDF–3.3M

Select item 97188238.

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal

Paola Cattaneo, Michael G. B. Hayes, Nina Baumgarten, Dennis Hecker, Sofia Peruzzo, Galip S. Aslan, Paolo Kunderfranco, Veronica Larcher, Lunfeng Zhang, Riccardo Contu, Gregory Fonseca, Simone Spinozzi, Ju Chen, Gianluigi Condorelli, Stefanie Dimmeler, Marcel H. Schulz, Sven Heinz, Nuno Guimarães-Camboa, Sylvia M. Evans

Nat Commun. 2022; 13: 7444. Published online 2022 Dec 2. doi: 10.1038/s41467-022-35070-2

PMCID:: PMC9718823

Abstract Article PDF–9.4M

Select item 90166199.

SIRT1 regulates cardiomyocyte alignment during maturation

Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K. Janoshazi, David C. Fargo, Xiaoling Li

J Cell Sci. 2022 Apr 1; 135(7): jcs259076. Published online 2022 Apr 1. doi: 10.1242/jcs.259076

PMCID:: PMC9016619

Abstract Article

Select item 885469410.

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas

Nat Commun. 2022; 13: 941. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28590-4

PMCID:: PMC8854694

Abstract Article PDF–15M

Select item 871060511.

Phosphoproteomic Analysis Reveals Downstream PKA Effectors of AKAP Cypher/ZASP in the Pathogenesis of Dilated Cardiomyopathy

Jialan Lv, Zhicheng Pan, Jian Chen, Rui Xu, Dongfei Wang, Jiaqi Huang, Yang Dong, Jing Jiang, Xiang Yin, Hongqiang Cheng, Xiaogang Guo

Front Cardiovasc Med. 2021; 8: 753072. Published online 2021 Dec 13. doi: 10.3389/fcvm.2021.753072

PMCID:: PMC8710605

Abstract Article PDF–5.2M

Select item 849615512.

Deletion of Sphingosine 1‐Phosphate receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

Ryan Jorgensen, Meghna Katta, Jayne Wolfe, Desiree F. Leach, Bianca Lavelle, Jerold Chun, Lisa D. Wilsbacher

Physiol Rep. 2021 Oct; 9(19): e15060. Published online 2021 Oct 7. doi: 10.14814/phy2.15060

PMCID:: PMC8496155

Abstract Article PDF–2.8M

Select item 820042313.

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Li‐Kai Tsai, I‐Hsin Chen, Chi‐Chao Chao, Hsueh‐Wen Hsueh, Hsin‐Hsiung Chen, Yun‐Hsin Huang, Rong‐Wei Weng, Tzu‐Yun Lai, Yi‐Chieh Tsai, Yeou‐Ping Tsao, Show‐Li Chen

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 665–676. Published online 2021 Mar 26. doi: 10.1002/jcsm.12697

PMCID:: PMC8200423

Abstract Article PDF–11M

Select item 797977614.

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation

Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi

Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1

PMCID:: PMC7979776

Abstract Article PDF–5.3M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 781283216.

Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling

Yuxuan Guo, Yangpo Cao, Blake D. Jardin, Isha Sethi, Qing Ma, Behzad Moghadaszadeh, Emily C. Troiano, Neil Mazumdar, Michael A. Trembley, Eric M. Small, Guo-Cheng Yuan, Alan H. Beggs, William T. Pu

Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2008861118. Published online 2020 Dec 23. doi: 10.1073/pnas.2008861118

PMCID:: PMC7812832

Abstract Article PDF–4.3M

Select item 778258917.

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function

Xinyun Chen, Ying Liu, Chen Xu, Lina Ba, Zhuo Liu, Xiuya Li, Jie Huang, Ed Simpson, Hongyu Gao, Dayan Cao, Wei Sheng, Hanping Qi, Hongrui Ji, Maria Sanderson, Chen-Leng Cai, Xiaohui Li, Lei Yang, Jie Na, Kenichi Yamamura, Yunlong Liu, Guoying Huang, Weinian Shou, Ning Sun

Nat Commun. 2021; 12: 89. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20327-5

PMCID:: PMC7782589

Abstract Article PDF–8.6M

Select item 771001618.

Differential physiological roles for BIN1 isoforms in skeletal muscle development, function and regeneration

Ivana Prokic, Belinda S. Cowling, Candice Kutchukian, Christine Kretz, Hichem Tasfaout, Vincent Gache, Josiane Hergueux, Olivia Wendling, Arnaud Ferry, Anne Toussaint, Christos Gavriilidis, Vasugi Nattarayan, Catherine Koch, Jeanne Lainé, Roy Combe, Laurent Tiret, Vincent Jacquemond, Fanny Pilot-Storck, Jocelyn Laporte

Dis Model Mech. 2020 Nov 1; 13(11): dmm044354. Published online 2020 Nov 24. doi: 10.1242/dmm.044354

PMCID:: PMC7710016

Abstract Article

Select item 761535919.

Characterization of a common progenitor pool of the epicardium and myocardium

Richard C.V. Tyser, Ximena Ibarra-Soria, Katie McDole, Satish A. Jayaram, Jonathan Godwin, Teun A.H. van den Brand, Antonio M.A. Miranda, Antonio Scialdone, Philipp J. Keller, John C. Marioni, Shankar Srinivas

Science. Author manuscript; available in PMC 2023 Dec 18.

Published in final edited form as: Science. 2021 Mar 5; 371(6533): eabb2986. Published online 2021 Jan 7. doi: 10.1126/science.abb2986

PMCID:: PMC7615359

Abstract Article PDF–3.9M

Select item 739093920.

The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology

Carrie E Barnum, Salma Al Saai, Shaili D Patel, Catherine Cheng, Deepti Anand, Xiaolu Xu, Soma Dash, Archana D Siddam, Lisa Glazewski, Emily Paglione, Shawn W Polson, Shinichiro Chuma, Robert W Mason, Shuo Wei, Mona Batish, Velia M Fowler, Salil A Lachke

Hum Mol Genet. 2020 Jul 29; 29(12): 2076–2097. Published online 2020 May 18. doi: 10.1093/hmg/ddaa096

PMCID:: PMC7390939

Abstract Article PDF–4.1M

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