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Select item 107808961.

RREB1 regulates neuronal proteostasis and the microtubule network

Emily N. Griffin, Thomas Jucius, Su-Eon Sim, Belinda S. Harris, Sven Heinz, Susan L. Ackerman

Sci Adv. 2024 Jan 12; 10(2): eadh3929. Published online 2024 Jan 10. doi: 10.1126/sciadv.adh3929

PMCID:: PMC10780896

Abstract Article PDF–4.8M

Select item 83132392.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 76749563.

Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model

Zhiqi Song, Yanfeng Xu, Ling Zhang, Li Zhou, Yu Zhang, Yunlin Han, Xianglei Li, Pin Yu, Yajin Qu, Wenjie Zhao, Chuan Qin

Front Genet. 2020; 11: 565479. Published online 2020 Nov 5. doi: 10.3389/fgene.2020.565479

PMCID:: PMC7674956

Abstract Article PDF–11M

Select item 75155704.

The effect of MD1 on potassium and L-type calcium current of cardiomyocytes from high-fat diet mice

Wei Shuai, Bin Kong, Hui Fu, Xiaobo Jiang, He Huang

Channels (Austin) 2020; 14(1): 181–189. Published online 2020 Jun 3. doi: 10.1080/19336950.2020.1772628

PMCID:: PMC7515570

Abstract Article PDF–1.8M

Select item 74176895.

MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway

Hong‐Jie Yang, Bin Kong, Wei Shuai, Jing‐jing Zhang, He Huang

J Cell Mol Med. 2020 Aug; 24(16): 9300–9312. Published online 2020 Jul 10. doi: 10.1111/jcmm.15579

PMCID:: PMC7417689

Abstract Article PDF–1.8M

Select item 69831966.

Myeloid Differentiation Protein 2 Mediates Angiotensin II-Induced Liver Inflammation and Fibrosis in Mice

Yi Zhang, Hui Liu, Wenjing Jia, Jiayu Qi, Wentao Zhang, Wenxin Zhang, Guang Liang, Yali Zhang, Hongjin Chen

Molecules. 2020 Jan; 25(1): 25. Published online 2019 Dec 19. doi: 10.3390/molecules25010025

PMCID:: PMC6983196

Abstract Article PDF–1.8M

Select item 63298317.

Single-cell transcriptomic analysis of mouse neocortical development

Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka

Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9

PMCID:: PMC6329831

Abstract Article PDF–3.6M

Select item 55059508.

Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling

Jianye Peng, Yu Liu, Xiaoju Xiong, Congxin Huang, Yang Mei, Zhiqiang Wang, Yanhong Tang, Jing Ye, Bin Kong, Wanli Liu, Teng Wang, He Huang

Sci Rep. 2017; 7: 5116. Published online 2017 Jul 11. doi: 10.1038/s41598-017-05379-w

PMCID:: PMC5505950

Abstract Article PDF–3.4M

Select item 52929629.

Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling

Xiaojv Xiong, Yu Liu, Yang Mei, Jianye Peng, Zhiqiang Wang, Bin Kong, Peng Zhong, Liang Xiong, Dajun Quan, Qi Li, Guangji Wang, He Huang

Sci Rep. 2017; 7: 41857. Published online 2017 Feb 6. doi: 10.1038/srep41857

PMCID:: PMC5292962

Abstract Article PDF–2.5M

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 336220311.

An unusual dimeric structure and assembly for RP105–MD-1, a regulator for the TLR4 response to LPS

Sung-il Yoon, Minsun Hong, Ian A. Wilson

Nat Struct Mol Biol. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: Nat Struct Mol Biol. 2011 Aug 21; 18(9): 1028–1035. Published online 2011 Aug 21. doi: 10.1038/nsmb.2106

PMCID:: PMC3362203

Abstract Article PDF–6.1M

Select item 333175812.

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Yasuharu Watanabe, Tomoya Nakamura, Sho Ishikawa, Shiho Fujisaka, Isao Usui, Koichi Tsuneyama, Yoshinori Ichihara, Tsutomu Wada, Yoichiro Hirata, Takayoshi Suganami, Hirofumi Izaki, Shizuo Akira, Kensuke Miyake, Hiro-omi Kanayama, Michio Shimabukuro, Masataka Sata, Toshiyasu Sasaoka, Yoshihiro Ogawa, Kazuyuki Tobe, Kiyoshi Takatsu, Yoshinori Nagai

Diabetes. 2012 May; 61(5): 1199–1209. Published online 2012 Apr 13. doi: 10.2337/db11-1182

PMCID:: PMC3331758

Abstract Article PDF–2.4M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304626014.

Identification of Anchor Genes during Kidney Development Defines Ontological Relationships, Molecular Subcompartments and Regulatory Pathways

Rathi D. Thiagarajan, Kylie M. Georgas, Bree A. Rumballe, Emmanuelle Lesieur, Han Sheng Chiu, Darrin Taylor, Dave T. P. Tang, Sean M. Grimmond, Melissa H. Little

PLoS One. 2011; 6(2): e17286. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017286

PMCID:: PMC3046260

Abstract Article PDF–982K

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 275213016.

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

Alison H. Harrill, Paul B. Watkins, Stephen Su, Pamela K. Ross, David E. Harbourt, Ioannis M. Stylianou, Gary A. Boorman, Mark W. Russo, Richard S. Sackler, Stephen C. Harris, Philip C. Smith, Raymond Tennant, Molly Bogue, Kenneth Paigen, Christopher Harris, Tanupriya Contractor, Timothy Wiltshire, Ivan Rusyn, David W. Threadgill

Genome Res. 2009 Sep; 19(9): 1507–1515. doi: 10.1101/gr.090241.108

PMCID:: PMC2752130

Abstract Article PDF–1.1M

Select item 219421517.

Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2: Higher Affinity than That with MD-2 or CD14

Sachiko Akashi, Shin-ichiroh Saitoh, Yasutaka Wakabayashi, Takane Kikuchi, Noriaki Takamura, Yoshinori Nagai, Yutaka Kusumoto, Koichi Fukase, Shoichi Kusumoto, Yoshiyuki Adachi, Atsushi Kosugi, Kensuke Miyake

J Exp Med. 2003 Oct 6; 198(7): 1035–1042. doi: 10.1084/jem.20031076

PMCID:: PMC2194215

Abstract Article PDF–348K

Select item 219308618.

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Rintaro Shimazu, Sachiko Akashi, Hirotaka Ogata, Yoshinori Nagai, Kenji Fukudome, Kensuke Miyake, Masao Kimoto

J Exp Med. 1999 Jun 7; 189(11): 1777–1782. doi: 10.1084/jem.189.11.1777

PMCID:: PMC2193086

Abstract Article PDF–142K

Select item 188770919.

The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

Hirotaka Ogata, I-hsin Su, Kensuke Miyake, Yoshinori Nagai, Sachiko Akashi, Ingrid Mecklenbräuker, Klaus Rajewsky, Masao Kimoto, Alexander Tarakhovsky

J Exp Med. 2000 Jul 3; 192(1): 23–30. doi: 10.1084/jem.192.1.23

PMCID:: PMC1887709

Abstract Article PDF–233K

Select item 141356820.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

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