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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105811452.

MiR-130a-3p Has Protective Effects in Alzheimer’s Disease via Targeting DAPK1

Yanbo Wang, Min Shi, Zhenmei Hong, Junling Kang, Haiyan Pan, Ci Yan

Am J Alzheimers Dis Other Demen. 2021 Jan-Dec; 36: 15333175211020572. Published online 2021 Jun 15. doi: 10.1177/15333175211020572

PMCID:: PMC10581145

Abstract Article PDF–399K

Select item 100955163.

Ablation of Death-Associated Protein Kinase 1 Changes the Transcriptomic Profile and Alters Neural-Related Pathways in the Brain

Ruomeng Li, Shuai Zhi, Guihua Lan, Xiaotong Chen, Xiuzhi Zheng, Li Hu, Long Wang, Tao Zhang, Tae Ho Lee, Shitao Rao, Dongmei Chen

Int J Mol Sci. 2023 Apr; 24(7): 6542. Published online 2023 Mar 31. doi: 10.3390/ijms24076542

PMCID:: PMC10095516

Abstract Article PDF–3.4M

Select item 92234304.

Blocking ERK-DAPK1 Axis Attenuates Glutamate Excitotoxicity in Epilepsy

Chen-Ling Gan, Yulian Zou, Dongmei Chen, Xindong Shui, Li Hu, Ruomeng Li, Tao Zhang, Junhao Wang, Yingxue Mei, Long Wang, Mi Zhang, Yuan Tian, Xi Gu, Tae Ho Lee

Int J Mol Sci. 2022 Jun; 23(12): 6370. Published online 2022 Jun 7. doi: 10.3390/ijms23126370

PMCID:: PMC9223430

Abstract Article PDF–3.5M

Select item 91424775.

MicroRNA-26b-5p Targets DAPK1 to Reduce Intestinal Ischemia/Reperfusion Injury via Inhibition of Intestinal Mucosal Cell Apoptosis

Bowei Zhou, Wenjuan Zhang, Zhengzheng Yan, Bingcheng Zhao, Jin Zhao, Weijie Feng, Xiaodong Chen, Cai Li, Ke-Xuan Liu

Dig Dis Sci. 2022; 67(5): 1794–1805. Published online 2021 Apr 10. doi: 10.1007/s10620-021-06975-7

PMCID:: PMC9142477

Abstract Article PDF–11M

Select item 88618746.

MicroRNA-26a/Death-associated protein kinase 1 signaling induces synucleinopathy and dopaminergic neuron degeneration in Parkinson’s disease

Ying Su, Man-Fei Deng, Wan Xiong, Ao-Ji Xie, Jifeng Guo, Zhi-Hou Liang, Bo Hu, Jian-Guo Chen, Xiongwei Zhu, Heng-Ye Man, Youming Lu, Dan Liu, Beisha Tang, Ling-Qiang Zhu

Biol Psychiatry. Author manuscript; available in PMC 2022 Feb 22.

Published in final edited form as: Biol Psychiatry. 2019 May 1; 85(9): 769–781. Published online 2018 Dec 19. doi: 10.1016/j.biopsych.2018.12.008

PMCID:: PMC8861874

Abstract Article PDF–3.2M

Select item 87418527.

Death-associated protein kinase 1 mediates Aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in Alzheimer's disease

Tao Zhang, Yongfang Xia, Li Hu, Dongmei Chen, Chen-Ling Gan, Long Wang, Yingxue Mei, Guihua Lan, Xindong Shui, Yuan Tian, Ruomeng Li, Mi Zhang, Tae Ho Lee

Int J Biol Sci. 2022; 18(2): 693–706. Published online 2022 Jan 1. doi: 10.7150/ijbs.66760

PMCID:: PMC8741852

Abstract Article PDF–1.8M

Select item 83567668.

Young DAPK1 knockout mice have altered presynaptic function

Dayton J. Goodell, Jonathan E. Tullis, K. Ulrich Bayer

J Neurophysiol. 2021 May 1; 125(5): 1973–1981. Published online 2021 Apr 21. doi: 10.1152/jn.00055.2021

PMCID:: PMC8356766

Abstract Article

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 824173710.

Inhibition of Death-associated Protein Kinase 1 protects against Epileptic Seizures in mice

Chen-Ling Gan, Yulian Zou, Yongfang Xia, Tao Zhang, Dongmei Chen, Guihua Lan, Yingxue Mei, Long Wang, Xindong Shui, Li Hu, Hekun Liu, Tae Ho Lee

Int J Biol Sci. 2021; 17(9): 2356–2366. Published online 2021 Jun 11. doi: 10.7150/ijbs.59922

PMCID:: PMC8241737

Abstract Article PDF–1.4M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 789004612.

Melatonin directly binds and inhibits death-associated protein kinase 1 function in Alzheimer’s disease

Dongmei Chen, Yingxue Mei, Nami Kim, Guihua Lan, Chen-Ling Gan, Fei Fan, Tao Zhang, Yongfang Xia, Long Wang, Chun Lin, Fang Ke, Xiao Zhen Zhou, Kun Ping Lu, Tae Ho Lee

J Pineal Res. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: J Pineal Res. 2020 Sep; 69(2): e12665. Published online 2020 May 27. doi: 10.1111/jpi.12665

PMCID:: PMC7890046

Abstract Article PDF–1.9M

Select item 785266013.

DAPK1 (death associated protein kinase 1) mediates mTORC1 activation and antiviral activities in CD8⁺ T cells

Zhengping Wei, Pingfei Li, Ran He, Huicheng Liu, Na Liu, Yu Xia, Guoyu Bi, Qiuyang Du, Minghui Xia, Lei Pei, Jing Wang, Guihua Wang, Zhao-Hui Tang, Xiang Cheng, Huabin Li, Zhuoya Li, Lilin Ye, Arian Laurence, Youming Lu, Xiang-Ping Yang

Cell Mol Immunol. 2021 Jan; 18(1): 138–149. Published online 2019 Sep 20. doi: 10.1038/s41423-019-0293-2

PMCID:: PMC7852660

Abstract Article PDF–4.9M

Select item 754600714.

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI

Bang-Chuan Hu, Guo-Hua Wu, Zi-Qiang Shao, Yang Zheng, Jin-Quan Liu, Run Zhang, Jun Hong, Xiang-Hong Yang, Ren-Hua Sun, Shi-Jing Mo

Theranostics. 2020; 10(25): 11479–11496. Published online 2020 Sep 15. doi: 10.7150/thno.49870

PMCID:: PMC7546007

Abstract Article PDF–3.4M

Select item 724585215.

Hyperthermia depletes Oct4 in mouse blastocysts and stem cells

Mo-bin Cheng, Xue Wang, Yue Huang, Ye Zhang

Stem Cell Res Ther. 2020; 11: 195. Published online 2020 May 24. doi: 10.1186/s13287-020-01715-6

PMCID:: PMC7245852

Abstract Article PDF–818K

Select item 719849216.

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

Yung-Hsuan Wu, Ting-Fang Chou, Leslie Young, Fu-Yi Hsieh, Hsuan-Yin Pan, Shu-Ting Mo, Shani Bialik Brown, Ruey-Hwa Chen, Adi Kimchi, Ming-Zong Lai

Cell Death Dis. 2020 May; 11(5): 305. Published online 2020 May 4. doi: 10.1038/s41419-020-2534-9

PMCID:: PMC7198492

Abstract Article PDF–3.6M

Select item 695913117.

CaMKII versus DAPK1 Binding to GluN2B in Ischemic Neuronal Cell Death after Resuscitation from Cardiac Arrest

Olivia R. Buonarati, Sarah G. Cook, Dayton J. Goodell, Nicholas E. Chalmers, Nicole L. Rumian, Jonathan E. Tullis, Susana Restrepo, Steven J. Coultrap, Nidia Quillinan, Paco S. Herson, K. Ulrich Bayer

Cell Rep. Author manuscript; available in PMC 2020 Jan 14.

Published in final edited form as: Cell Rep. 2020 Jan 7; 30(1): 1–8.e4. doi: 10.1016/j.celrep.2019.11.076

PMCID:: PMC6959131

Abstract Article PDF–1.4M

Select item 662091418.

G-Protein-Coupled Receptor 30 Mediates Rapid Neuroprotective Effects of Estrogen via Depression of NR2B-Containing NMDA Receptors

Shui-bing Liu, Nan Zhang, Yan-yan Guo, Rong Zhao, Tian-yao Shi, Shu-fang Feng, Shi-quan Wang, Qi Yang, Xiao-qiang Li, Yu-mei Wu, Lan Ma, Ying Hou, Li-ze Xiong, Weiqi Zhang, Ming-gao Zhao

J Neurosci. 2012 Apr 4; 32(14): 4887–4900. doi: 10.1523/JNEUROSCI.5828-11.2012

PMCID:: PMC6620914

Abstract Article PDF–4.4M

Select item 660814119.

DAPK1–p53 Interaction Converges Necrotic and Apoptotic Pathways of Ischemic Neuronal Death

Lei Pei, You Shang, Huijuan Jin, Shan Wang, Na Wei, Honglin Yan, Yan Wu, Chengye Yao, Xiaoxi Wang, Ling-Qiang Zhu, Youming Lu

J Neurosci. 2014 May 7; 34(19): 6546–6556. doi: 10.1523/JNEUROSCI.5119-13.2014

PMCID:: PMC6608141

Abstract Article PDF–2.9M

Select item 608656320.

Inhibition of death-associated protein kinase 1 attenuates the phosphorylation and amyloidogenic processing of amyloid precursor protein

Byeong Mo Kim, Mi-Hyeon You, Chun-Hau Chen, Jaehong Suh, Rudolph E. Tanzi, Tae Ho Lee

Hum Mol Genet. 2016 Jun 15; 25(12): 2498–2513. Published online 2016 Apr 19. doi: 10.1093/hmg/ddw114

PMCID:: PMC6086563

Abstract Article PDF–1.0M

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