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Items: 1 to 20 of 566

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia
Natasha Malik, Jodie Hay, Hassan N. B. Almuhanna, Karen M. Dunn, Jamie Lees, Jennifer Cassels, Jiatian Li, Rinako Nakagawa, Owen J. Sansom, Alison M. Michie
Leukemia. 2023; 37(12): 2414–2425. Published online 2023 Sep 29. doi: 10.1038/s41375-023-02043-3
PMCID:
PMC10681897
AbstractArticlePDF–4.8M
3.
Host B cells escape CAR-T immunotherapy by reversible downregulation of CD19
Sara Fioretti, Courtney A. Matson, Kenneth M. Rosenberg, Nevil J. Singh
Cancer Immunol Immunother. 2023 Jan; 72(1): 257–264. Published online 2022 Jun 26. doi: 10.1007/s00262-022-03231-3
PMCID:
PMC10608797
AbstractArticlePDF–3.0M
4.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation
Coraline Mlynarczyk, Matt Teater, Juhee Pae, Christopher R. Chin, Ling Wang, Theinmozhi Arulraj, Darko Barisic, Antonin Papin, Kenneth B. Hoehn, Ekaterina Kots, Jonatan Ersching, Arnab Bandyopadhyay, Ersilia Barin, Hui Xian Poh, Chiara M. Evans, Amy Chadburn, Zhengming Chen, Hao Shen, Hannah M. Isles, Benedikt Pelzer, Ioanna Tsialta, Ashley S. Doane, Huimin Geng, Muhammad Hassan Rehman, Jonah Melnick, Wyatt Morgan, Diu T. T. Nguyen, Olivier Elemento, Michael G. Kharas, Samie R. Jaffrey, David W. Scott, George Khelashvili, Michael Meyer-Hermann, Gabriel D. Victora, Ari Melnick
Science. Author manuscript; available in PMC 2023 Sep 22.
Published in final edited form as: Science. 2023 Jan 20; 379(6629): eabj7412. Published online 2023 Jan 20. doi: 10.1126/science.abj7412
PMCID:
PMC10515739
AbstractArticlePDF–3.1M
5.
PHRF1 promotes the class switch recombination of IgA in CH12F3-2A cells
Jin-Yu Lee, Nai-Lin Chou, Ya-Ru Yu, Hsin-An Shih, Hung-Wei Lin, Chine-Kuo Lee, Mau-Sun Chang
PLoS One. 2023; 18(8): e0285159. Published online 2023 Aug 4. doi: 10.1371/journal.pone.0285159
PMCID:
PMC10403053
AbstractArticlePDF–2.1M
6.
STAT3 signaling in B cells controls germinal center zone organization and recycling
Adam J. Fike, Sathi Babu Chodisetti, Nathaniel E. Wright, Kristen N. Bricker, Phillip P. Domeier, Mark Maienschein-Cline, Aaron M. Rosenfeld, Sara A. Luckenbill, Julia L. Weber, Nicholas M. Choi, Eline T. Luning Prak, Malay Mandal, Marcus R. Clark, Ziaur S.M. Rahman
Cell Rep. Author manuscript; available in PMC 2023 Jun 30.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112512. Published online 2023 May 16. doi: 10.1016/j.celrep.2023.112512
PMCID:
PMC10311431
AbstractArticlePDF–3.8M
7.
Atlas of the anatomical localization of atypical chemokine receptors in healthy mice
Serena Melgrati, Egle Radice, Rafet Ameti, Elin Hub, Sylvia Thelen, Pawel Pelczar, David Jarrossay, Antal Rot, Marcus Thelen
PLoS Biol. 2023 May; 21(5): e3002111. Published online 2023 May 9. doi: 10.1371/journal.pbio.3002111
PMCID:
PMC10198502
AbstractArticlePDF–7.8M
8.
Distinct oncogenic phenotypes in hematopoietic specific deletions of Trp53
Jayanth Kumar Palanichamy, Tiffany M. Tran, Jennifer K. King, Sol Katzman, Alexander J. Ritter, Gunjan Sharma, Christine Tso, Jorge R. Contreras, Thilini R. Fernando, Jeremy R. Sanford, Dinesh S. Rao
Sci Rep. 2023; 13: 7490. Published online 2023 May 9. doi: 10.1038/s41598-023-33949-8
PMCID:
PMC10169790
AbstractArticlePDF–2.2M
9.
CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells
Megan R. McCaleb, Anjelica M. Miranda, Kaysie C. Ratliff, Raul M. Torres, Roberta Pelanda
Immunohorizons. 2023 Jan 1; 7(1): 49–63. Published online 2023 Jan 13. doi: 10.4049/immunohorizons.2200092
PMCID:
PMC10074640
AbstractArticlePDF–1.9M
10.
Upregulated expression of the IL-9 receptor on TRAF3-deficient B lymphocytes confers the immunoglobulin isotype switching responsiveness to IL-9 in the presence of antigen receptor engagement and IL-4
Samantha Gokhale, Eton Victor, Jemmie Tsai, Eris Spirollari, Brygida Matracz, Shogo Takatsuka, Jaeyong Jung, Daisuke Kitamura, Ping Xie
J Immunol. Author manuscript; available in PMC 2024 Apr 15.
Published in final edited form as: J Immunol. 2023 Apr 15; 210(8): 1059–1073. doi: 10.4049/jimmunol.2200563
PMCID:
PMC10073299
AbstractArticlePDF–2.7M
11.
CD40 drives CNS autoimmune disease by inducing complementary effector programs via B cells and dendritic cells
Ying Lu, Max Xu, Cayce E. Dorrier, Ray Zhang, Christian T. Mayer, David Wagner, Dorian B. McGavern, Richard J. Hodes
J Immunol. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: J Immunol. 2022 Dec 1; 209(11): 2083–2092. doi: 10.4049/jimmunol.2200439
PMCID:
PMC10065987
AbstractArticlePDF–2.1M
12.
In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities
Elisa ten Hacken, Tomasz Sewastianik, Shanye Yin, Gabriela Brunsting Hoffmann, Michaela Gruber, Kendell Clement, Livius Penter, Robert A. Redd, Neil Ruthen, Sébastien Hergalant, Alanna Sholokhova, Geoffrey Fell, Erin M. Parry, Julien Broséus, Romain Guieze, Fabienne Lucas, María Hernández-Sánchez, Kaitlyn Baranowski, Jackson Southard, Heather Joyal, Leah Billington, Fara Faye D. Regis, Elizabeth Witten, Mohamed Uduman, Binyamin A. Knisbacher, Shuqiang Li, Haoxiang Lyu, Tiziana Vaisitti, Silvia Deaglio, Giorgio Inghirami, Pierre Feugier, Stephan Stilgenbauer, Eugen Tausch, Matthew S. Davids, Gad Getz, Kenneth J. Livak, Ivana Bozic, Donna S. Neuberg, Ruben D. Carrasco, Catherine J. Wu
Blood Cancer Discov. 2023 Mar 1; 4(2): 150–169. Published online 2022 Dec 6. doi: 10.1158/2643-3230.BCD-22-0082
PMCID:
PMC9975769
AbstractArticlePDF–27M
13.
Dhx33 promotes B-cell growth and proliferation by controlling activation-induced rRNA upregulation
Xiaoyu He, Jiayi Zhao, Abidan Adilijiang, Peicheng Hong, Pengda Chen, Xinyong Lin, Jun Xie, Ying Du, Yun Liu, Lianghua Lin, Hyun Yong Jin, Yazhen Hong, Wen-Hsien Liu, Changchun Xiao
Cell Mol Immunol. 2023 Mar; 20(3): 277–291. Published online 2023 Jan 11. doi: 10.1038/s41423-022-00972-0
PMCID:
PMC9970960
AbstractArticlePDF–4.2M
14.
Low-affinity CTCF binding drives transcriptional regulation whereas high-affinity binding encompasses architectural functions
Ester Marina-Zárate, Ana Rodríguez-Ronchel, Manuel J. Gómez, Fátima Sánchez-Cabo, Almudena R. Ramiro
iScience. 2023 Mar 17; 26(3): 106106. Published online 2023 Feb 2. doi: 10.1016/j.isci.2023.106106
PMCID:
PMC9958374
AbstractArticlePDF–3.1M
15.
Transcription factor TFII-I fine tunes innate properties of B lymphocytes
Amit Singh, Mary Kaileh, Supriyo De, Krystyna Mazan-Mamczarz, Dashzeveg Bayarsaihan, Ranjan Sen, Ananda L. Roy
Front Immunol. 2023; 14: 1067459. Published online 2023 Jan 23. doi: 10.3389/fimmu.2023.1067459
PMCID:
PMC9900109
AbstractArticlePDF–25M
16.
Type I IFN receptor signaling on B cells promotes antibody responses to polysaccharide antigens
M. Ariel Spurrier, Jamie E. Jennings-Gee, Karen M. Haas
J Immunol. Author manuscript; available in PMC 2024 Jan 15.
Published in final edited form as: J Immunol. 2023 Jan 15; 210(2): 148–157. doi: 10.4049/jimmunol.2200538
PMCID:
PMC9812919
AbstractArticlePDF–997K
17.
Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis
Masashi Watanabe, Sofia Celli, Farrah A. Alkhaleel, Richard J. Hodes
Cell Rep. Author manuscript; available in PMC 2022 Dec 31.
Published in final edited form as: Cell Rep. 2022 Nov 29; 41(9): 111731. doi: 10.1016/j.celrep.2022.111731
PMCID:
PMC9805342
AbstractArticlePDF–2.1M
18.
Brain motor and fear circuits regulate leukocytes during acute stress
Wolfram C. Poller, Jeffrey Downey, Agnes A. Mooslechner, Nargis Khan, Long Li, Christopher T. Chan, Cameron S. McAlpine, Chunliang Xu, Florian Kahles, Shun He, Henrike Janssen, John E. Mindur, Sumnima Singh, Máté G. Kiss, Laura Alonso-Herranz, Yoshiko Iwamoto, Rainer H. Kohler, Lai Ping Wong, Kashish Chetal, Scott J. Russo, Ruslan I. Sadreyev, Ralph Weissleder, Matthias Nahrendorf, Paul S. Frenette, Maziar Divangahi, Filip K. Swirski
Nature. Author manuscript; available in PMC 2022 Dec 29.
Published in final edited form as: Nature. 2022 Jul; 607(7919): 578–584. Published online 2022 May 30. doi: 10.1038/s41586-022-04890-z
PMCID:
PMC9798885
AbstractArticlePDF–4.5M
19.
Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination
Hongchang Zhao, Stella R Hartono, Kirtney Mae Flores de Vera, Zheyuan Yu, Krishni Satchi, Tracy Zhao, Roger Sciammas, Lionel Sanz, Frédéric Chédin, Jacqueline Barlow
eLife. 2022; 11: e78917. Published online 2022 Dec 21. doi: 10.7554/eLife.78917
PMCID:
PMC9771370
AbstractArticlePDF–3.4M
20.
Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease
Tobias Petzold, Zhe Zhang, Iván Ballesteros, Inas Saleh, Amin Polzin, Manuela Thienel, Lulu Liu, Qurrat Ul Ain, Vincent Ehreiser, Christian Weber, Badr Kilani, Pontus Mertsch, Jeremias Götschke, Sophie Cremer, Wenwen Fu, Michael Lorenz, Hellen Ishikawa-Ankerhold, Elisabeth Raatz, Shaza El-Nemr, Agnes Görlach, Esther Marhuenda, Konstantin Stark, Joachim Pircher, David Stegner, Christian Gieger, Marc Schmidt-Supprian, Florian Gaertner, Isaac Almendros, Malte Kelm, Christian Schulz, Andrés Hidalgo, Steffen Massberg
Immunity. 2022 Dec 13; 55(12): 2285–2299.e7. doi: 10.1016/j.immuni.2022.10.001
PMCID:
PMC9767676
AbstractArticle

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