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Select item 43395221.

GADS is Required for TCR-Mediated Calcium Influx and Cytokine Release, but not Cellular Adhesion, in Human T Cells

Mahmood Y. Bilal, Elizabeth Y. Zhang, Brittney Dinkel, Daimon Hardy, Thomas M. Yankee, Jon C.D. Houtman

Cell Signal. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Cell Signal. 2015 Apr; 27(4): 841–850. Published online 2015 Jan 28. doi: 10.1016/j.cellsig.2015.01.012

PMCID:: PMC4339522

Abstract Article PDF–1.3M

Select item 49815002.

LC Gillis, DM Berry, MD Minden, CJ McGlade, DL Barber

Leukemia. Author manuscript; available in PMC 2016 Aug 11.

Published in final edited form as: Leukemia. 2013 Aug; 27(8): 1666–1676. Published online 2013 Feb 12. doi: 10.1038/leu.2013.40

PMCID:: PMC4981500

Abstract Article PDF–2.6M

Select item 21930193.

Che-Leung Law, Maria K. Ewings, Preet M. Chaudhary, Sasha A. Solow, Theodore J. Yun, Aaron J. Marshall, Leroy Hood, Edward A. Clark

J Exp Med. 1999 Apr 19; 189(8): 1243–1253. doi: 10.1084/jem.189.8.1243

PMCID:: PMC2193019

Abstract Article PDF–455K

Select item 54406464.

T Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex

Johannes Breuning, Marion H. Brown

Mol Cell Biol. 2017 Jun 1; 37(11): e00071-17. Prepublished online 2017 Mar 13. Published online 2017 May 16. doi: 10.1128/MCB.00071-17

PMCID:: PMC5440646

Abstract Article PDF–530K

Select item 11710735.

Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.

R P Bourette, S Arnaud, G M Myles, J P Blanchet, L R Rohrschneider, G Mouchiroud

EMBO J. 1998 Dec 15; 17(24): 7273–7281. doi: 10.1093/emboj/17.24.7273

PMCID:: PMC1171073

Summary PDF–358K

Select item 52476396.

Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins

Satomi Inaba, Nobutaka Numoto, Shuhei Ogawa, Hisayuki Morii, Teikichi Ikura, Ryo Abe, Nobutoshi Ito, Masayuki Oda

J Biol Chem. 2017 Jan 20; 292(3): 1052–1060. Published online 2016 Dec 6. doi: 10.1074/jbc.M116.755173

PMCID:: PMC5247639

Abstract Article PDF–2.1M

Select item 28904747.

SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering

Hebin Liu, Marco A. Purbhoo, Daniel M. Davis, Christopher E. Rudd

Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22): 10166–10171. Published online 2010 May 13. doi: 10.1073/pnas.0909112107

PMCID:: PMC2890474

Abstract Article PDF–672K

Select item 41869648.

CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription

Helga Schneider, Christopher E. Rudd

Biochem Biophys Res Commun. Author manuscript; available in PMC 2014 Oct 7.

Published in final edited form as: Biochem Biophys Res Commun. 2008 May 2; 369(2): 616–621. Published online 2008 Feb 22. doi: 10.1016/j.bbrc.2008.02.068

PMCID:: PMC4186964

Abstract Article PDF–656K

Select item 21930529.

Grf40, A Novel Grb2 Family Member, Is Involved in T Cell Signaling through Interaction with SLP-76 and LAT

Hiroshi Asada, Naoto Ishii, Yoshiteru Sasaki, Kazuhiro Endo, Hirotake Kasai, Nobuyuki Tanaka, Toshikazu Takeshita, Shigeru Tsuchiya, Tasuke Konno, Kazuo Sugamura

J Exp Med. 1999 May 3; 189(9): 1383–1390. doi: 10.1084/jem.189.9.1383

PMCID:: PMC2193052

Abstract Article PDF–324K

Select item 179439210.

Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif

Bruce T Seet, Donna M Berry, Jonathan S Maltzman, Jacob Shabason, Monica Raina, Gary A Koretzky, C Jane McGlade, Tony Pawson

EMBO J. 2007 Feb 7; 26(3): 678–689. Published online 2007 Jan 18. doi: 10.1038/sj.emboj.7601535

PMCID:: PMC1794392

Abstract Article PDF–618K

Select item 13381311.

Induced Expression and Association of the Mona/Gads Adapter and Gab3 Scaffolding Protein during Monocyte/Macrophage Differentiation

Caroline Bourgin, Roland P. Bourette, Sylvie Arnaud, Yan Liu, Larry R. Rohrschneider, Guy Mouchiroud

Mol Cell Biol. 2002 Jun; 22(11): 3744–3756. doi: 10.1128/MCB.22.11.3744-3756.2002

PMCID:: PMC133813

Abstract Article PDF–673K

Select item 300226612.

Histidine Domain-Protein Tyrosine Phosphatase Interacts with Grb2 and GrpL

Carmen-Alexandra Tanase

PLoS One. 2010; 5(12): e14339. Published online 2010 Dec 15. doi: 10.1371/journal.pone.0014339

PMCID:: PMC3002266

Abstract Article PDF–483K

Select item 285956113.

AMSH Interacts with ESCRT-0 to Regulate the Stability and Trafficking of CXCR4

Maria I. Sierra, Michelle H. Wright, Piers D. Nash

J Biol Chem. 2010 Apr 30; 285(18): 13990–14004. Published online 2010 Feb 16. doi: 10.1074/jbc.M109.061309

PMCID:: PMC2859561

Abstract Article PDF–2.4M

Select item 15675514.

Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

Maria Harkiolaki, Marc Lewitzky, Robert J.C. Gilbert, E.Yvonne Jones, Roland P. Bourette, Guy Mouchiroud, Holger Sondermann, Ismail Moarefi, Stephan M. Feller

EMBO J. 2003 Jun 2; 22(11): 2571–2582. doi: 10.1093/emboj/cdg258

PMCID:: PMC156755

Abstract Article PDF–557K

Select item 331875815.

Once Phosphorylated, Tyrosines in Carboxyl Terminus of Protein-tyrosine Kinase Syk Interact with Signaling Proteins, Including TULA-2, a Negative Regulator of Mast Cell Degranulation

Rodrigo Orlandini de Castro, Juan Zhang, Jacqueline R. Groves, Emilia Alina Barbu, Reuben P. Siraganian

J Biol Chem. 2012 Mar 9; 287(11): 8194–8204. Published online 2012 Jan 20. doi: 10.1074/jbc.M111.326850

PMCID:: PMC3318758

Abstract Article PDF–2.9M

Select item 410389316.

Identification of SH3 Domain Proteins Interacting with the Cytoplasmic Tail of the A Disintegrin and Metalloprotease 10 (ADAM10)

Henriette Ebsen, Marcus Lettau, Dieter Kabelitz, Ottmar Janssen

PLoS One. 2014; 9(7): e102899. Published online 2014 Jul 18. doi: 10.1371/journal.pone.0102899

PMCID:: PMC4103893

Abstract Article PDF–1.2M

Select item 275648717.

Keeping the (Kinase) Party Going: SLP-76 and ITK Dance to the Beat

Qian Qi, Avery August

Sci STKE. Author manuscript; available in PMC 2009 Oct 4.

Published in final edited form as: Sci STKE. 2007 Jul 24; 2007(396): pe39. Published online 2007 Jul 24. doi: 10.1126/stke.3962007pe39

PMCID:: PMC2756487

Abstract Article PDF–1009K

Select item 14101418.

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

Arthur R. Salomon, Scott B. Ficarro, Laurence M. Brill, Achim Brinker, Qui T. Phung, Christer Ericson, Karsten Sauer, Ansgar Brock, David M. Horn, Peter G. Schultz, Eric C. Peters

Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2): 443–448. Published online 2003 Jan 9. doi: 10.1073/pnas.2436191100

PMCID:: PMC141014

Abstract Article PDF–152K

Select item 671572519.

Maximizing binary interactome mapping with a minimal number of assays

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Luke Lambourne, Kerstin Spirohn, Irma Lemmens, Mélanie Dos Santos, Caroline Demeret, Louis Jones, Sudharshan Rangarajan, Wenting Bian, Eloi P. Coutant, Yves L. Janin, Sylvie van der Werf, Philipp Trepte, Erich E. Wanker, Javier De Las Rivas, Jan Tavernier, Jean-Claude Twizere, Tong Hao, David E. Hill, Marc Vidal, Michael A. Calderwood, Yves Jacob

Nat Commun. 2019; 10: 3907. Published online 2019 Aug 29. doi: 10.1038/s41467-019-11809-2

PMCID:: PMC6715725

Abstract Article PDF–1.7M

Select item 1031267420.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

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PMC Links for Gene (Select 9402) (42)
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PREDICTED: Mus musculus predicted gene, 36408 (Gm36408), transcript variant X3, ...
PREDICTED: Mus musculus predicted gene, 36408 (Gm36408), transcript variant X3, ncRNA
gi|1907175319|ref|XR_004933823.1|

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