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Select item 62844321.

The core planar cell polarity gene, Vangl2, maintains apical‐basal organisation of the corneal epithelium

D. Alessio Panzica, Amy S. Findlay, Rianne van Ladesteijn, J. Martin Collinson

J Anat. 2019 Jan; 234(1): 106–119. Published online 2017 Aug 17. doi: 10.1111/joa.12676

PMCID:: PMC6284432

Article PDF–1.2M

Select item 60756082.

Bimodal regulation of Dishevelled function by Vangl2 during morphogenesis

Hwa-Seon Seo, Raymond Habas, Chenbei Chang, Jianbo Wang

Hum Mol Genet. 2017 Jun 1; 26(11): 2053–2061. Published online 2017 Mar 13. doi: 10.1093/hmg/ddx095

PMCID:: PMC6075608

Article PDF–717K

Select item 101939793.

An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation

Yeon Sun Kim, Jia Yuan, Amanda Dewar, Jean-Paul Borg, David W. Threadgill, Xiaofei Sun, Sudhansu K. Dey

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2302937120. Published online 2023 May 8. doi: 10.1073/pnas.2302937120

PMCID:: PMC10193979

Article PDF–3.3M

Select item 89879254.

Vangl2 Promotes Hematopoietic Stem Cell Expansion

Sarah Bouali, Roxann Hétu-Arbour, Célia Gardet, Krista M. Heinonen

Front Cell Dev Biol. 2022; 10: 760248. Published online 2022 Mar 24. doi: 10.3389/fcell.2022.760248

PMCID:: PMC8987925

Article PDF–4.5M

Select item 88075815.

Vangl2–environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension

Oleksandr Nychyk, Gabriel L. Galea, Matteo Molè, Dawn Savery, Nicholas D. E. Greene, Philip Stanier, Andrew J. Copp

Dis Model Mech. 2022 Jan 1; 15(1): dmm049194. Published online 2022 Jan 26. doi: 10.1242/dmm.049194

PMCID:: PMC8807581

Article

Select item 78834346.

Silencing of Vangl2 attenuates the inflammation promoted by Wnt5a via MAPK and NF-κB pathway in chondrocytes

Ke Zhang, Zhuoying Li, Yunyang Lu, Linyi Xiang, Jiadong Sun, Hong Zhang

J Orthop Surg Res. 2021; 16: 136. Published online 2021 Feb 15. doi: 10.1186/s13018-021-02268-x

PMCID:: PMC7883434

Article PDF–2.5M

Select item 72963507.

Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion

Benjamin J.A. Robert, Maïté M. Moreau, Steve Dos Santos Carvalho, Gael Barthet, Claudia Racca, Mehdi Bhouri, Anne Quiedeville, Maurice Garret, Bénédicte Atchama, Alice Shaam Al Abed, Christelle Guette, Deborah J. Henderson, Aline Desmedt, Christophe Mulle, Aline Marighetto, Mireille Montcouquiol, Nathalie Sans

Cell Rep. 2020 Jun 9; 31(10): 107743. Published online 2020 Jun 9. doi: 10.1016/j.celrep.2020.107743

PMCID:: PMC7296350

Article

Select item 67410638.

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

Cristy Tower-Gilchrist, Stephanie A. Zlatic, Dehong Yu, Qing Chang, Hao Wu, Xi Lin, Victor Faundez, Ping Chen

Mol Biol Cell. 2019 Aug 15; 30(18): 2422–2434. doi: 10.1091/mbc.E16-08-0592

PMCID:: PMC6741063

Article PDF–2.3M

Select item 63935369.

Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

Tadahiro Nagaoka, Mikio Furuse, Toshihisa Ohtsuka, Kunihiro Tsuchida, Masashi Kishi

Sci Rep. 2019; 9: 2912. Published online 2019 Feb 27. doi: 10.1038/s41598-019-39642-z

PMCID:: PMC6393536

Article PDF–1.8M

Select item 628274410.

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury

Eugenia Papakrivopoulou, Elisavet Vasilopoulou, Maja T Lindenmeyer, Sabrina Pacheco, Hortensja Ł Brzóska, Karen L Price, Maria Kolatsi‐Joannou, Kathryn E White, Deborah J Henderson, Charlotte H Dean, Clemens D Cohen, Alan D Salama, Adrian S Woolf, David A Long

J Pathol. 2018 Dec; 246(4): 485–496. Published online 2018 Nov 16. doi: 10.1002/path.5158

PMCID:: PMC6282744

Article PDF–3.2M

Select item 527846811.

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

Sonal Thakar, Liqing Wang, Ting Yu, Mao Ye, Keisuke Onishi, John Scott, Jiaxuan Qi, Catarina Fernandes, Xuemei Han, John R. Yates, III, Darwin K. Berg, Yimin Zou

Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): E610–E618. Published online 2017 Jan 5. doi: 10.1073/pnas.1612062114

PMCID:: PMC5278468

Article PDF–2.3M

Select item 422178312.

Vangl2 Regulates E-Cadherin in Epithelial Cells

Tadahiro Nagaoka, Ayumu Inutsuka, Khadiza Begum, Khandakar musabbir bin hafiz, Masashi Kishi

Sci Rep. 2014; 4: 6940. Published online 2014 Nov 6. doi: 10.1038/srep06940

PMCID:: PMC4221783

Article PDF–1.2M

Select item 346087013.

Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

Edwige Belotti, Tania M. Puvirajesinghe, Stéphane Audebert, Emilie Baudelet, Luc Camoin, Michel Pierres, Lea Lasvaux, Géraldine Ferracci, Mireille Montcouquiol, Jean-Paul Borg

PLoS One. 2012; 7(9): e46213. Published online 2012 Sep 28. doi: 10.1371/journal.pone.0046213

PMCID:: PMC3460870

Article PDF–747K

Select item 337870014.

Nitric Oxide Sustains Long-Term Skeletal Muscle Regeneration by Regulating Fate of Satellite Cells Via Signaling Pathways Requiring Vangl2 and Cyclic GMP

Roberta Buono, Chiara Vantaggiato, Viviana Pisa, Emanuele Azzoni, Maria Teresa Bassi, Silvia Brunelli, Clara Sciorati, Emilio Clementi

Stem Cells. 2012 Feb; 30(2): 197–209. Published online 2011 Nov 14. doi: 10.1002/stem.783

PMCID:: PMC3378700

Article PDF–4.2M

Select item 297628815.

When whorls collide: the development of hair patterns in frizzled 6 mutant mice

Yanshu Wang, Hao Chang, Jeremy Nathans

Development. 2010 Dec 1; 137(23): 4091–4099. doi: 10.1242/dev.057455

PMCID:: PMC2976288

Article

Select item 1028964816.

VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation

Zhiqiang Hu, Yingchao Xie, Jiansen Lu, Jianwu Yang, Jiahuan Zhang, Huaji Jiang, Hongyu Li, Yufeng Zhang, Dan Wu, Ke Zeng, Xiaochun Bai, Xiao Yu

Sci Adv. 2023 Jun; 9(25): eadg2339. Published online 2023 Jun 23. doi: 10.1126/sciadv.adg2339

PMCID:: PMC10289648

Article PDF–2.6M

Select item 846389617.

Cannabinoid and planar cell polarity signaling converges to direct placentation

Yeon Sun Kim, Yingju Li, Jia Yuan, Jean-Paul Borg, Xiaofei Sun, Sudhansu K. Dey

Proc Natl Acad Sci U S A. 2021 Sep 21; 118(38): e2108201118. Published online 2021 Sep 14. doi: 10.1073/pnas.2108201118

PMCID:: PMC8463896

Article PDF–3.2M

Select item 580754818.

Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation

Jia Yuan, Wenbo Deng, Jeeyeon Cha, Xiaofei Sun, Jean-Paul Borg, Sudhansu. K. Dey

Nat Commun. 2018; 9: 603. Published online 2018 Feb 9. doi: 10.1038/s41467-018-03092-4

PMCID:: PMC5807548

Article PDF–10M

Select item 420482319.

Sperm-Associated Antigen 6 (SPAG6) Deficiency and Defects in Ciliogenesis and Cilia Function: Polarity, Density, and Beat

Maria E. Teves, Patrick R. Sears, Wei Li, Zhengang Zhang, Waixing Tang, Lauren van Reesema, Richard M. Costanzo, C. William Davis, Michael R. Knowles, Jerome F. Strauss, III, Zhibing Zhang

PLoS One. 2014; 9(10): e107271. Published online 2014 Oct 21. doi: 10.1371/journal.pone.0107271

PMCID:: PMC4204823

Article PDF–8.9M

Select item 406728020.

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

Arnaud P. Giese, Jérome Ezan, Lingyan Wang, Léa Lasvaux, Frédérique Lembo, Claire Mazzocco, Elodie Richard, Jérome Reboul, Jean-Paul Borg, Matthew W. Kelley, Nathalie Sans, John Brigande, Mireille Montcouquiol

Development. 2012 Oct 15; 139(20): 3775–3785. doi: 10.1242/dev.074229