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Select item 110308931.

Lung carcinomas do not induce T-cell apoptosis via the Fas/Fas ligand pathway but down-regulate CD3 epsilon expression

Heriberto Prado-Garcia, Dolores Aguilar-Cazares, Manuel Meneses-Flores, Jorge Morales-Fuentes, Jose Sullivan Lopez-Gonzalez

Cancer Immunol Immunother. 2008 Mar; 57(3): 325–336. Published online 2007 Aug 1. doi: 10.1007/s00262-007-0372-6

PMCID:: PMC11030893

Abstract Article PDF–635K

Select item 35263572.

Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain

Etienne Gagnon, David A. Schubert, Susana Gordo, H. Hamlet Chu, Kai W. Wucherpfennig

J Exp Med. 2012 Dec 17; 209(13): 2423–2439. doi: 10.1084/jem.20120790

PMCID:: PMC3526357

Abstract Article PDF–4.4M

Select item 21961713.

Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood

Ludovica Bruno, Pieter Res, Mark Dessing, Marina Cella, Hergen Spits

J Exp Med. 1997 Mar 3; 185(5): 875–884. doi: 10.1084/jem.185.5.875

PMCID:: PMC2196171

Abstract Article PDF–300K

Select item 21928864.

Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells

J Exp Med. 1996 Nov 1; 184(5): 1901–1908. doi: 10.1084/jem.184.5.1901

PMCID:: PMC2192886

Summary PDF–928K

Select item 21922525.

Physical dissociation of the TCR-CD3 complex accompanies receptor ligation

J Exp Med. 1995 Dec 1; 182(6): 1997–2006. doi: 10.1084/jem.182.6.1997

PMCID:: PMC2192252

Summary PDF–1.1M

Select item 21919686.

Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment

J Exp Med. 1995 Apr 1; 181(4): 1445–1458. doi: 10.1084/jem.181.4.1445

PMCID:: PMC2191968

Summary PDF–3.8M

Select item 15354667.

Susceptibility to type I diabetes in women is associated with the CD3 epsilon locus on chromosome 11.

S Wong, S Moore, S Orisio, A Millward, A G Demaine

Clin Exp Immunol. 1991 Jan; 83(1): 69–73. doi: 10.1111/j.1365-2249.1991.tb05590.x

PMCID:: PMC1535466

Summary Page Browse PDF–815K

Select item 2823868.

Human CD3-epsilon gene contains three miniexons and is transcribed from a non-TATA promoter.

H C Clevers, S Dunlap, T E Wileman, C Terhorst

Proc Natl Acad Sci U S A. 1988 Nov; 85(21): 8156–8160. doi: 10.1073/pnas.85.21.8156

PMCID:: PMC282386

Summary Page Browse PDF–1.0M

Select item 448209.

A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene.

B Wang, C Biron, J She, K Higgins, M J Sunshine, E Lacy, N Lonberg, C Terhorst

Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20): 9402–9406. doi: 10.1073/pnas.91.20.9402

PMCID:: PMC44820

Summary Page Browse PDF–1.0M

Select item 920357910.

Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient

Gebremedhin Gebremicael, Atsbeha Gebreegziabxier, Desta Kassa

Sci Rep. 2022; 12: 10133. Published online 2022 Jun 16. doi: 10.1038/s41598-022-14305-8

PMCID:: PMC9203579

Abstract Article PDF–2.8M

Select item 701164611.

Actin polymerization regulates recruitment of Nck to CD3ε upon T‐cell receptor triggering

Piyamaporn Wipa, Pussadee Paensuwan, Jatuporn Ngoenkam, Nadine M. Woessner, Susana Minguet, Wolfgang W. Schamel, Sutatip Pongcharoen

Immunology. 2020 Mar; 159(3): 298–308. Published online 2019 Nov 26. doi: 10.1111/imm.13146

PMCID:: PMC7011646

Abstract Article PDF–1.6M

Select item 553067012.

Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling

Lunyi Li, Xingdong Guo, Xiaoshan Shi, Changting Li, Wei Wu, Chengsong Yan, Haopeng Wang, Hua Li, Chenqi Xu

Proc Natl Acad Sci U S A. 2017 Jul 18; 114(29): E5891–E5899. Published online 2017 Jun 28. doi: 10.1073/pnas.1701990114

PMCID:: PMC5530670

Abstract Article PDF–2.6M

Select item 257785213.

Structural and functional evidence that Nck interaction with CD3ε regulates T cell receptor activity

Koh Takeuchi, Hailin Yang, Elise Ng, Sungh-youk Park, Zhen-Yu J. Sun, Ellis L. Reinherz, Gerhard Wagner

J Mol Biol. Author manuscript; available in PMC 2009 Jul 18.

Published in final edited form as: J Mol Biol. 2008 Jul 18; 380(4): 704–716. Published online 2008 May 22. doi: 10.1016/j.jmb.2008.05.037

PMCID:: PMC2577852

Abstract Article PDF–1.6M

Select item 256628414.

The Quality of Chimpanzee T-Cell Activation and Simian Immunodeficiency Virus/Human Immunodeficiency Virus Susceptibility Achieved via Antibody-Mediated T-Cell Receptor/CD3 Stimulation Is a Function of the Anti-CD3 Antibody Isotype

Frederic Bibollet-Ruche, Brett A. McKinney, Alexandra Duverger, Frederic H. Wagner, Aftab A. Ansari, Olaf Kutsch

J Virol. 2008 Oct; 82(20): 10271–10278. Published online 2008 Jul 30. doi: 10.1128/JVI.01319-08

PMCID:: PMC2566284

Abstract Article PDF–1.1M

Select item 52897715.

Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragment

Kelly L. Arnett, Stephen C. Harrison, Don C. Wiley

Proc Natl Acad Sci U S A. 2004 Nov 16; 101(46): 16268–16273. Published online 2004 Nov 8. doi: 10.1073/pnas.0407359101

PMCID:: PMC528977

Abstract Article PDF–672K

Select item 52574516.

Severe combined immunodeficiency caused by deficiency in either the δ or the ε subunit of CD3

Geneviève de Saint Basile, Frédéric Geissmann, Elisabeth Flori, Béatrice Uring-Lambert, Claire Soudais, Marina Cavazzana-Calvo, Anne Durandy, Nada Jabado, Alain Fischer, Françoise Le Deist

J Clin Invest. 2004 Nov 15; 114(10): 1512–1517. doi: 10.1172/JCI22588

PMCID:: PMC525745

Abstract Article PDF–562K

Select item 520724417.

The Stalk Domain of NKp30 Contributes to Ligand Binding and Signaling of a Preassembled NKp30-CD3ζ Complex

Stefanie Memmer, Sandra Weil, Steffen Beyer, Tobias Zöller, Eike Peters, Jessica Hartmann, Alexander Steinle, Joachim Koch

J Biol Chem. 2016 Dec 2; 291(49): 25427–25438. Published online 2016 Oct 17. doi: 10.1074/jbc.M116.742981

PMCID:: PMC5207244

Abstract Article PDF–2.2M

Select item 4185718.

Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.

J Y Bu, A S Shaw, A C Chan

Proc Natl Acad Sci U S A. 1995 May 23; 92(11): 5106–5110. doi: 10.1073/pnas.92.11.5106

PMCID:: PMC41857

Summary Page Browse PDF–1.1M

Select item 452814019.

Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR

Yanan He, Sneha Rangarajan, Melissa Kerzic, Ming Luo, Yihong Chen, Qian Wang, Yiyuan Yin, Creg J. Workman, Kate M. Vignali, Dario A. A. Vignali, Roy A. Mariuzza, John Orban

J Biol Chem. 2015 Aug 7; 290(32): 19796–19805. Published online 2015 Jun 24. doi: 10.1074/jbc.M115.663799

PMCID:: PMC4528140

Abstract Article PDF–2.2M

Select item 426735720.

Molecular architecture of the αβ T cell receptor–CD3 complex

Michael E. Birnbaum, Richard Berry, Yu-Shan Hsiao, Zhenjun Chen, Miguel A. Shingu-Vazquez, Xiaoling Yu, Deepa Waghray, Suzanne Fischer, James McCluskey, Jamie Rossjohn, Thomas Walz, K. Christopher Garcia

Proc Natl Acad Sci U S A. 2014 Dec 9; 111(49): 17576–17581. Published online 2014 Nov 24. doi: 10.1073/pnas.1420936111