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Select item 77538721.

Identification of mini‐chromosome maintenance 8 as a potential prognostic marker and its effects on proliferation and apoptosis in gastric cancer

Bin Huang, Minghe Lin, Lisha Lu, Wujin Chen, Jingzhuang Tan, Jinyan Zhao, Zhiyun Cao, Xiaoqin Zhu, Jiumao Lin

J Cell Mol Med. 2020 Dec; 24(24): 14415–14425. Published online 2020 Nov 6. doi: 10.1111/jcmm.16062

PMCID:: PMC7753872

Article PDF–2.2M

Select item 75265382.

Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome

Mariano Golubicki, Laia Bonjoch, José G. Acuña-Ochoa, Marcos Díaz-Gay, Jenifer Muñoz, Miriam Cuatrecasas, Teresa Ocaña, Soledad Iseas, Guillermo Mendez, Daniel Cisterna, Stephanie A. Schubert, Maartje Nielsen, Tom van Wezel, Yael Goldberg, Eli Pikarsky, Juan Robbio, Enrique Roca, Antoni Castells, Francesc Balaguer, Marina Antelo, Sergi Castellví-Bel

JCI Insight. 2020 Sep 17; 5(18): e140698. Published online 2020 Sep 17. doi: 10.1172/jci.insight.140698

PMCID:: PMC7526538

Article PDF–20M

Select item 75075663.

Two novel mutations in the MCM8 gene shared by two Chinese siblings with primary ovarian insufficiency and short stature

Fei Wang, Sheng Guo, Pin Li

Mol Genet Genomic Med. 2020 Sep; 8(9): e1396. Published online 2020 Jul 11. doi: 10.1002/mgg3.1396

PMCID:: PMC7507566

Article PDF–1.2M

Select item 71964584.

Novel loss‐of‐function mutation in MCM8 causes premature ovarian insufficiency

Ya‐Xin Zhang, Wen‐Bin He, Wen‐Juan Xiao, Lan‐Lan Meng, Chen Tan, Juan Du, Guang‐Xiu Lu, Ge Lin, Yue‐Qiu Tan

Mol Genet Genomic Med. 2020 Apr; 8(4): e1165. Published online 2020 Feb 11. doi: 10.1002/mgg3.1165

PMCID:: PMC7196458

Article PDF–838K

Select item 54814625.

Oncogenic Activity of Amplified Miniature Chromosome Maintenance 8 in Human Malignancies

Dong-Mei He, Bao-Guo Ren, Silvia Liu, Lang-Zhu Tang, Kathleen Cieply, George Tseng, Yan P. Yu, Jian-Hua Luo

Oncogene. Author manuscript; available in PMC 2017 Nov 8.

Published in final edited form as: Oncogene. 2017 Jun 22; 36(25): 3629–3639. Published online 2017 May 8. doi: 10.1038/onc.2017.123

PMCID:: PMC5481462

Article PDF–1.0M

Select item 47135176.

Expression of minichromosome maintenance 8 in chronic myelogenous leukemia

Lili Cai, Kai Zhao, Xuejie Yuan

Int J Clin Exp Pathol. 2015; 8(11): 14180–14188. Published online 2015 Nov 1.

PMCID:: PMC4713517

Article PDF–691K

Select item 43822577.

Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability

Saleh AlAsiri, Sulman Basit, Michelle A. Wood-Trageser, Svetlana A. Yatsenko, Elizabeth P. Jeffries, Urvashi Surti, Deborah M. Ketterer, Sibtain Afzal, Khushnooda Ramzan, Muhammad Faiyaz-Ul Haque, Huaiyang Jiang, Michael A. Trakselis, Aleksandar Rajkovic

J Clin Invest. 2015 Jan 2; 125(1): 258–262. Published online 2014 Dec 1. doi: 10.1172/JCI78473

PMCID:: PMC4382257

Article PDF–1.1M

Select item 34706918.

Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities

Sonya M. Schuh-Huerta, Nicholas A. Johnson, Mitchell P. Rosen, Barbara Sternfeld, Marcelle I. Cedars, Renee A. Reijo Pera

Hum Genet. 2012; 131(11): 1709–1724. Published online 2012 Jun 13. doi: 10.1007/s00439-012-1184-0

PMCID:: PMC3470691

Article PDF–946K

Select item 1405029.

Identification and functional characterization of a new member of the human Mcm protein family: hMcm8

Devrim Gozuacik, Mounia Chami, David Lagorce, Jamila Faivre, Yoshiki Murakami, Olivier Poch, Esther Biermann, Rolf Knippers, Christian Bréchot, Patrizia Paterlini-Bréchot

Nucleic Acids Res. 2003 Jan 15; 31(2): 570–579. doi: 10.1093/nar/gkg136

PMCID:: PMC140502

Article PDF–393K

Select item 1041514110.

Activity, substrate preference and structure of the HsMCM8/9 helicase

David R McKinzey, Chuxuan Li, Yang Gao, Michael A Trakselis

Nucleic Acids Res. 2023 Aug 11; 51(14): 7330–7341. Published online 2023 Jun 13. doi: 10.1093/nar/gkad508

PMCID:: PMC10415141

Article PDF–1.8M

Select item 1028644611.

Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics

Yu-meng Sun, Yi-meng Zhang, Hai-liang Shi, Song Yang, Yin-long Zhao, Hong-jiang Liu, Chen Li, Hong-lei Liu, Ji-peng Yang, Jian Song, Guo-zhu Sun, Jian-kai Yang

Hereditas. 2023; 160: 29. Published online 2023 Jun 22. doi: 10.1186/s41065-023-00292-x

PMCID:: PMC10286446

Article PDF–5.3M

Select item 802738012.

Knockdown of MCM8 functions as a strategy to inhibit the development and progression of osteosarcoma through regulating CTGF

Zhinan Ren, Jun Li, Shanwen Zhao, Qi Qiao, Runguang Li

Cell Death Dis. 2021 Apr; 12(4): 376. Published online 2021 Apr 7. doi: 10.1038/s41419-021-03621-y

PMCID:: PMC8027380

Article PDF–3.4M

Select item 639888313.

Inhibiting the MCM8‐9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Issay Morii, Yukiko Iwabuchi, Sumiko Mori, Masaki Suekuni, Toyoaki Natsume, Kazumasa Yoshida, Nozomi Sugimoto, Masato T. Kanemaki, Masatoshi Fujita

Cancer Sci. 2019 Mar; 110(3): 1044–1053. Published online 2019 Feb 14. doi: 10.1111/cas.13941

PMCID:: PMC6398883

Article PDF–883K

Select item 543589314.

Acute inactivation of the replicative helicase in human cells triggers MCM8–9-dependent DNA synthesis

Toyoaki Natsume, Kohei Nishimura, Sheroy Minocherhomji, Rahul Bhowmick, Ian D. Hickson, Masato T. Kanemaki

Genes Dev. 2017 Apr 15; 31(8): 816–829. doi: 10.1101/gad.297663.117

PMCID:: PMC5435893

Article PDF–457K

Select item 541316115.

MCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency

Swapna Desai, Michelle Wood-Trageser, Jelena Matic, Jaqueline Chipkin, Huaiyang Jiang, Anne Bachelot, Jerome Dulon, Cinzia Sala, Caterina Barbieri, Massimiliano Cocca, Daniela Toniolo, Philippe Touraine, Selma Witchel, Aleksandar Rajkovic

J Clin Endocrinol Metab. 2017 Feb 1; 102(2): 576–582. Published online 2016 Nov 1. doi: 10.1210/jc.2016-2565

PMCID:: PMC5413161

Article

Select item 664111416.

Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma

Kang Liu, Min Kang, Xiwen Liao, Rensheng Wang

PLoS One. 2019; 14(7): e0219467. Published online 2019 Jul 19. doi: 10.1371/journal.pone.0219467

PMCID:: PMC6641114

Article PDF–9.2M

Select item 328412117.

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study

Christina T. L. Chen, Lindsay Fernández-Rhodes, Robert G. Brzyski, Christopher S. Carlson, Zhao Chen, Gerardo Heiss, Kari E. North, Nancy F. Woods, Aleksandar Rajkovic, Charles Kooperberg, Nora Franceschini

Hum Mol Genet. 2012 Mar 15; 21(6): 1419–1432. Published online 2011 Nov 30. doi: 10.1093/hmg/ddr570

PMCID:: PMC3284121

Article PDF–439K

Select item 677139218.

Control of homologous recombination by the HROB–MCM8–MCM9 pathway

Nicole Hustedt, Yuichiro Saito, Michal Zimmermann, Alejandro Álvarez-Quilón, Dheva Setiaputra, Salomé Adam, Andrea McEwan, Jing Yi Yuan, Michele Olivieri, Yichao Zhao, Masato T. Kanemaki, Andrea Jurisicova, Daniel Durocher

Genes Dev. 2019 Oct 1; 33(19-20): 1397–1415. doi: 10.1101/gad.329508.119

PMCID:: PMC6771392

Article PDF–6.3M

Select item 15672819.

A new member of the MCM protein family encoded by the human MCM8 gene, located contrapodal to GCD10 at chromosome band 20p12.3–13

Edward M. Johnson, Yayoi Kinoshita, Dianne C. Daniel

Nucleic Acids Res. 2003 Jun 1; 31(11): 2915–2925. doi: 10.1093/nar/gkg395

PMCID:: PMC156728

Article PDF–358K

Select item 362424420.

The MCM8-MCM9 Complex Promotes RAD51 Recruitment at DNA Damage Sites To Facilitate Homologous Recombination

Jonghoon Park, David T. Long, Kyung Yong Lee, Tarek Abbas, Etsuko Shibata, Masamitsu Negishi, Yunhai Luo, John C. Schimenti, Agnieszka Gambus, Johannes C. Walter, Anindya Dutta

Mol Cell Biol. 2013 Apr; 33(8): 1632–1644. doi: 10.1128/MCB.01503-12